Clinical trials: HIV/AIDS, Medication Adherence
Health Risk Behaviors
Feasibility, Acceptability, and Preliminary Efficacy of an HIV Prevention Intervention for Older Black Women
The goal of this clinical trial is to learn whether a group-based HIV prevention program can improve HIV knowledge, prevention behaviors, and testing in older Black women aged 50 and older who live in subsidized housing.
- Trial name
- NCT07181616
- Testing
- Adapted W2W, Waitlist Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laneshia Conner
ART, Hiv
Strengthening Families Living With HIV in Kenya
This study seeks to use a group-based microfinance/internal lending model to develop social capital among people with HIV in Kenya.
- Conditions
- ART, Hiv, Trust, Depression, Anxiety
- Trial name
- NCT04588883
- Testing
- Kuja Pamoja - HIV
- Where
- Kenya
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Adherence, Medication, Risk Reduction
Prevention and Risk: Treatment With a New Emphasis on Relationships
This research examines the efficacy of an individually-delivered intervention tailored for YMSM in relationships. The intervention - termed PARTNER - utilizes a brief (4 session) motivational interviewing format to target…
- Conditions
- Adherence, Medication, Risk Reduction, Drug Use, Sex, Anal
- Trial name
- PARTNER (NCT03396367)
- Testing
- PARTNER, Education Intervention
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
HIV Infections
Automated Medication Platform With Video Observation and Facial Recognition to Improve Adherence to Antiretroviral Therapy in Patients With HIV/AIDS
This is a 90-day medication adherence study testing the HiDO is an automated AI-driven direct observation medication adherence platform, which is a 510K-exempt, Class I medical device with 24 people with HIV/AIDS, ages 18 to 55…
- Trial name
- NCT05454514
- Testing
- HiDO medication adherence platform, Automated Medication Platform with Video Observation, Time on Task
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Charles Gellman
HIV
Mental Health and Medication Adherence Among MSM in South Africa
The goal of this behavioral study is to improve psychological well-being and optimization of HIV prevention and care outcomes for Men who have sex with men (MSM) in South Africa.
- Trial name
- NCT06880172
- Testing
- WeCare
- Where
- South Africa
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections, Adherence, Medication
Transmasculine One-on-One and Group Empowerment for Targeted HIV Reduction
Transgender masculine and gender diverse people who have sex with men (TMSM) have an increased risk of human immunodeficiency virus (HIV) and face unique barriers engaging in prevention services.
- Trial name
- TOGETHR (NCT06182280)
- Testing
- PrEP4T, LS4TM
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Chlamydia Infections, Gonorrhea
Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections
Project FEDE-ITS will improve the STI knowledge and its treatment, of adolescents in the 1st and 2nd year of compulsory secondary education in the intervention group compared to compared to the control group, and will modify the…
- Conditions
- Chlamydia Infections, Gonorrhea, Syphilis Infection, Human Immunodeficiency Virus (HIV)
- Trial name
- FEDE-ITS (NCT05727033)
- Testing
- Participatory teaching group
- Where
- 4 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
HIV Infection, HCV Coinfection
Testing and Linkage to Care for Injecting Drug Users in Kenya
Testing and Linkage to Care for Injecting Drug Users in Kenya: Interventions for people who inject drugs (PWID) in sub-Saharan African have been almost entirely absent, despite the fact that in countries like Kenya they…
- Trial name
- NCT01557998
- Testing
- POC CD4 and Peer Case Management, HCV+PWID, Control - No intervention
- Where
- Kenya
- Volunteers
- 9,449 people, healthy volunteers welcome
- Sponsor
- Yale University
Medication Adherence, HIV/AIDS
A Mobile Gaming App to Improve Adherence to PrEP
In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi.
- Trial name
- NCT05762705
- Testing
- Multilevel Gaming Adherence Intervention, Treatment as Usual +
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV, Alcoholism
Will Having Alcohol Treatment Improve Functioning?
The purpose of the study is to find out if a medication,naltrexone is helpful for HIV-infected women who sometimes drink too much.
- Trial name
- WHAT-IF (NCT01245647)
- Testing
- Naltrexone, 50mg, once per day for 4 months, Sugar pill, 50mg, once per day for 4 months
- Where
- 3 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Florida
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
HIV/AIDS
PeerNaija: A Mobile Health Platform Incentivizing Medication Adherence Among Youth Living With HIV in Nigeria
The PEERNaija application will feature routine medication reminders, along with individual adherence monitoring with adherence scores, anonymized peer adherence scores (from peers attending the same clinic; social incentive), and…
- Trial name
- NCT04930198
- Testing
- PeerNaija
- Where
- 2 sites in Nigeria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Human Immunodeficiency Virus (HIV) Infection, HIV Prevention
Empowering Knowledge, Self-Testing & Resilience Through Innovative Methods for HIV
The goal of this study is to learn whether a digital tool can help improve HIV knowledge, self-awareness, and testing among adolescents in Yogyakarta, Indonesia.
- Conditions
- Human Immunodeficiency Virus (HIV) Infection, HIV Prevention, Adolescent Health, Digital Education Interventions
- Trial name
- EKSTRIM (NCT07039682)
- Testing
- Digital HIV Education and Self-Screening (EKSTRIM Model)
- Where
- Indonesia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
Opioid-use Disorder, Adherence, Medication
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom.
- Conditions
- Opioid-use Disorder, Adherence, Medication, HIV Infections
- Trial name
- NCT04479475
- Testing
- Supportive care through community support persons
- Where
- Tanzania
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV, Tuberculosis
Evaluation of South Africa's National Adherence Strategy
NOTE THAT THE STUDY IS LED BY SOUTH AFRICA NATIONAL DEPARTMENT OF HEALTH AND WORLD BANK WITH SUPPORT FROM BOSTON UNIVERSITY. The South Africa National Department of Health (NDOH) intends to launch its newly developed National…
- Conditions
- HIV, Tuberculosis, Diabetes, Hypertension
- Trial name
- ENHANCE (NCT02536768)
- Testing
- Minimum package of interventions to improve ART adherence
- Where
- South Africa
- Volunteers
- 8,020 people, healthy volunteers welcome
- Sponsor
- Boston University
Depression, Medication Adherence
Cognitive Behavioral Therapy on Adherence and Depression (CBT-AD) Among HIV/AIDS Patients
Depression is highly comorbid with HIV/ AIDS and is associated with worse poor adherence to antiretroviral therapy (ART), and potentially to long-term immune functioning. Cognitive behavioral therapy may solve these problem.
- Trial name
- NCT06109610
- Testing
- Cognitive Behavioral Therapy
- Where
- Ethiopia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Mattu University
HIV Infections
Triggered Escalating Real-time Adherence (TERA) Intervention
Youth Living with HIV (YLWH) often face unique challenges achieving high and sustained rates of adherence to their antiretroviral therapy (ART).
- Trial name
- TERA (NCT03292432)
- Testing
- TERA Intervention (TERA), Standard of Care (SOC)
- Where
- 8 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Disorder With Hyperactivity
Parent-Provider Intervention for Improving Medication Adherence in Children With Attention Deficit Hyperactivity Disorder
This three-phase study will develop and test a provider-administered intervention to improve medication adherence and promote sustained medication use among children with ADHD and their caregivers.
- Trial name
- NCT00429221
- Testing
- Tailored Medication Messages for Parents
- Volunteers
- healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Adherence, Medication, HIV Prevention
Pharmacy-based PrEP for Young Women Who Sell Sex in Zimbabwe
Pharmacy-based PrEP for Young Women who Sell Sex in Zimbabwe is a cluster-randomized control trial and pilot study co-led by Dr.
- Trial name
- TOPAZ (NCT06348069)
- Testing
- Pharmacy-based PrEP refill and gift voucher, Control (Standard of care)
- Where
- Zimbabwe
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Adherence, Medication, Adolescent Behavior
Youth-focused Strategies to Promote Adherence to Pre-exposure Prophylaxis Among Youth At-risk for HIV in Thailand
A randomized controlled clinical trial looking at the effect of use of a mobile phone application in addition to standard care compared to standard care alone at a youth-friendly clinic in young men who have sex with men and…
- Conditions
- Adherence, Medication, Adolescent Behavior, HIV Prevention, Sexual Health
- Trial name
- YouthPrEP (NCT03778892)
- Testing
- 'Project Raincoat' Mobile Phone Application
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University