Clinical trials: HIV Infection, completed
HIV Infections
A Study of Stem Cells and Filgrastim
To determine the safety of stem cell harvesting after administration of filgrastim ( G-CSF ) to mobilize bone marrow stem cells into the peripheral blood in patients at various stages of HIV-1 infection as well as in HIV-negative…
- Trial name
- NCT00001071
- Testing
- Filgrastim
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cervical Cancer Screening
Improving Cervical Cancer Screening in Women Living With HIV Attending Chronic Disease Clinics in Semi-rural Tanzania
This study is to analyse the effect of a bundle of measures on the proportion of females being screened for cervical cancer in the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO), comparing the time period before…
- Trial name
- NCT05256862
- Testing
- Data collection
- Where
- Tanzania
- Volunteers
- 2,974 people
- Sponsor
- University Hospital, Basel, Switzerland
HIV, HIV Infections
HIV Persistence and Viral Reservoirs
Although highly active antiretroviral therapy (HAART) decreases HIV-associated mortality, it does not to completely restore health.
- Trial name
- NCT01025427
- Testing
- Raltegravir, tenofovir/emtricitabine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Francisco
HIV Infections
Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults
The purpose of this study is to evaluate the safety and immune response to three DNA vaccines and a MVA-CMDR vaccine that may boost the immune response to the DNA vaccines in healthy, HIV-uninfected adults.
- Trial name
- NCT02296541
- Testing
- DNA Nat-B env, DNA CON-S env, DNA Mosaic env
- Where
- 7 sites in United States, Switzerland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV-1 Infection
Safety and Efficacy of Bictegravir + Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected, Antiretroviral Treatment-Naive Adults
This study will evaluate the efficacy, safety and tolerability of bictegravir (BIC) + emtricitabine/tenofovir alafenamide (F/TAF) fixed dose combination (FDC) versus dolutegravir (DTG) + F/TAF in HIV-1 Infected, antiretroviral…
- Trial name
- NCT02397694
- Testing
- BIC, F/TAF, DTG
- Where
- 21 sites in United States
- Volunteers
- 98 people
- Sponsor
- Gilead Sciences
Hiv, Sexually Transmitted Infection
Expanding PrEP By Embedding Unannounced SNAPS Navigators in High STI Testing Clinical Sites
The goal of this study is to assess the impact of an intervention, known as SNAPS, to expand Preexposure Prophylaxis (PrEP) prescriptions at Health + Hospitals (H+H)/Bellevue.
- Trial name
- NCT04207151
- Testing
- SNAPS intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
HIV Infections
Situational Analysis of HIV-related Disability in the Context of Ivory Coast
The goal of this study is to document the impairment, functional and activity limitation and disability associated with HIV infection in an African urban context. It will combine quantitative and a qualitative methods.
- Trial name
- ViRAGE (NCT05199831)
- Where
- 2 sites in Côte d’Ivoire
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Programme PAC-CI, Site ANRS-MIE de Côte d'Ivoire
HIV Infections
A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection
To determine the relative antiviral activity and safety of zidovudine ( AZT ) and didanosine ( ddI ) alone and in combination, as well as in various sequences of administration.
- Trial name
- NCT00000823
- Testing
- Zidovudine, Didanosine
- Where
- 22 sites in United States
- Volunteers
- 85 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tuberculosis
A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 Administered in Adults
This Phase I study will be conducted as a randomized, double-blind, dose-escalation study in five groups of healthy adult male and female subjects who are BCG-vaccinated, HIV-negative, and have no evidence of tuberculosis…
- Trial name
- NCT02074956
- Testing
- AERAS-404
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aeras
HIV-1-infection
Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV
This study is designed to evaluate the safety and efficacy of lefitolimod and 3BNC117/10-1074 in HIV-1-infected individuals on ART and during ATI as intervention to reduce the HIV-1 reservoir
- Trial name
- TITAN (NCT03837756)
- Testing
- Saline, Lefitolimod, 3BNC117 and 10-1074
- Where
- 8 sites in United States, Australia and 2 more
- Volunteers
- 47 people
- Sponsor
- University of Aarhus
HIV Infection
Pharmacokinetic Study Of EPZICOM Tablet
This study was designed to explore the drug levels in the blood in Japanese HIV-infected patients taking EPZICOM tablet at least for 2 weeks prior to administration of the study drug.
- Trial name
- NCT00337922
- Testing
- Lamivudine / Abacavir Sulfate
- Where
- 4 sites in Japan
- Volunteers
- 8 people
- Sponsor
- GlaxoSmithKline
Depression, Hiv
Supervised Treadmill Intervention to Reduce Inflammation and Depression Through Exercise in HIV: The STRIDE Pilot Study
Depression in people living with HIV is associated with worse care engagement, drug adherence, and higher rates of pre-mature mortality.
- Trial name
- NCT06149624
- Testing
- upfront advice to walk, Supervised exercise
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Minnesota
HIV Infections, Sexually Transmitted Infections
HIV Prevention Program for African American Teen Males
The purpose of this study is to test if sexual health interventions can reduce the incidence of STIs among African American teens (15 to 21 years old).
- Trial name
- NCT00849823
- Testing
- Male Sexual Health Program, Focus on the Future Program
- Where
- United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Malaria in Pregnancy, HIV Infections
Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus Mefloquine
The purpose of this study is to evaluate the efficacy of cotrimoxazole prophylaxis in prevention of malaria during pregnancy in HIV-infected women, compared to intermittent preventive treatment with mefloquine.
- Trial name
- PACOME (NCT00970879)
- Testing
- cotrimoxazole, mefloquine
- Where
- 5 sites in Benin
- Volunteers
- 430 people
- Sponsor
- Institut de Recherche pour le Developpement
HIV Infections
'COMBINE-2': Real-world Evidence for Effectiveness of Two Drug Regimen, Antiretroviral Therapy With Integrase Inhibitors Plus a Reverse Transcriptase Inhibitor
Dolutegravir (DTG) is a well-tolerated 2nd generation integrase strand transfer inhibitor (INSTI); rilpivirine (RPV) is a well-tolerated non- nucleoside reverse transcriptase inhibitors (NNRTI) and lamivudine (3TC) is a…
- Trial name
- NCT04019873
- Testing
- Dolutegravir (DTG), Lamivudine (3TC), Rilpivirine (RPV)
- Where
- Spain
- Volunteers
- 774 people
- Sponsor
- ViiV Healthcare
Medication Adherence, HIV
Examining HIV Treatment Adherence During Early Disease
Determine the level, patterns, and correlates of objectively measured ART adherence in early and advanced-stage disease, among pregnant and non-pregnant individuals, to determine the need and nature of interventions to support…
- Trial name
- META (NCT02419066)
- Where
- 2 sites in South Africa, Uganda
- Volunteers
- 904 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Opioid Use, Marijuana
MEMO-Medical Marijuana and Opioids Study
The study will examine how medical cannabis use affects opioid analgesic use over time, with particular attention to THC/CBD content, HIV outcomes, and severe adverse events.
- Conditions
- Opioid Use, Marijuana, Chronic Pain, HIV/AIDS
- Trial name
- NCT03268551
- Where
- 2 sites in United States
- Volunteers
- 257 people
- Sponsor
- Albert Einstein College of Medicine
Hyperlipidemia, HIV Infections
Atazanavir or Boosted Atazanavir Substitution for Ritonavir Boosted PI in Patients With Hyperlipidemia
The study is looking to compare the impact of lipid levels and HIV viral loads between three different drug regimens: Continuing current regimen (ritonavir boosted regimen), Switching to Atazanavir, or Switching to Atazanavir in…
- Trial name
- NCT00160329
- Testing
- Atazanavir
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Hiv, HIV Infections
Adoptive Transfer of Haploidentical NK Cells and N-803
This is a pilot therapeutic study of related donor HLA-haploidentical NK-cell based therapy to determine if the treatment is safe and well-tolerated and if there is any measureable impact on virus reservoirs.
- Conditions
- Hiv, HIV Infections, Immune Deficiency
- Trial name
- NCT03899480
- Testing
- Haploidentical Natural Killer (NK) Cells
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Healthy Subjects, Infection, Human Immunodeficiency Virus
DDI Study of Etravirine and GSK1265744
The primary objective of this study is to compare steady-state plasma PK, safety and tolerability of GSK1265744 with and without etravirine
- Trial name
- NCT00920296
- Testing
- GSK1265744
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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