Clinical trials: HIV Infection, completed
Metabolic Syndromes, HIV Infection
Pilot Study of Metabolic Syndromes and HIV Infections in Indian Tibetans
Kaohsiung Medical University Chung-Ho Memorial Hospital will provide a long-term free medical service in Indian Tibetans since July 2010.
- Trial name
- NCT01261221
- Where
- Taiwan
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pregnancy, Malaria
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy
The study aims at comparing the safety, tolerability and efficacy of Mefloquine (MQ) to Sulfadoxine-Pyrimethamine (SP) as Interment Preventive Treatment in pregnancy (IPTp) for the prevention of malaria effects on the mother and…
- Conditions
- Pregnancy, Malaria, HIV Infections
- Trial name
- MiPPAD (NCT00811421)
- Testing
- Sulphadoxine-pyrimethamine, Mefloquine (full dose), Mefloquine (split dose)
- Where
- 5 sites in Benin, Gabon and 3 more
- Volunteers
- 5,820 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
HIV Infections, Depression
The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
The objective of this study is to evaluate the effect of ginkgo biloba (steady state) on the pharmacokinetics of a single dose of the UGT-substrate raltegravir. Furthermore the safety profile of the combination is studied.
- Conditions
- HIV Infections, Depression, Mild Cognitive Impairment
- Trial name
- GINGER (NCT01246804)
- Testing
- raltegravir single dose, ginkgo biloba multiple dose
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
HIV Infections
A Phase I Study to Evaluate the Safety and Toxicity of the Combination of Zidovudine and 2',3'-Dideoxyinosine (Didanosine) in Children With HIV Infection
To assess the safety and tolerance of the combination of zidovudine (AZT) and didanosine (ddI) in children with HIV infection. New approaches to using available agents may provide increased or improved treatment options for AIDS.
- Trial name
- NCT00000652
- Testing
- Zidovudine, Didanosine
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Cancer Institute (NCI)
HIV Infections, Memory
Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients
Despite the advent of highly active antiretroviral therapy (HAART), the prevalence of neurocognitive impairment among HIV-infected patients continues to be an important issue.
- Trial name
- NCT00893815
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Hiv
Assisted Partner Services and HIVST in Western Kenya
This study includes different designs with Aim 1 being a cluster randomized controlled trial to investigate the use of HIV self-testing (HIVST) as a mode of HIV testing in Western Kenya in addition to the standard of care…
- Trial name
- NCT04774835
- Testing
- HIVST, Standard aPS
- Where
- United States
- Volunteers
- 4,941 people
- Sponsor
- University of Washington
HIV Infection
Correlation of HIV Levels With Clinical and Immunologic Outcome in Children Treated With Didanosine
Recent studies have shown that patients receiving state-of-the-art treatment for HIV infection (highly active antiretroviral therapy, or HAART) show discordant responses to therapy-that is, they improve both clinically and…
- Trial name
- NCT00026676
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- National Cancer Institute (NCI)
HIV Infections
Case-Control Viramune (Nevirapine) Toxicogenomics Study
Attempt to identify genetic polymorphisms in interrogated pathways which may be associated with symptomatic hepatotoxicity or severe cutaneous toxicity observed in case patients within the first 8 weeks of nevirapine therapy.
- Trial name
- NCT00310843
- Testing
- Nevirapine
- Where
- 102 sites in United States, Argentina and 9 more
- Volunteers
- 889 people
- Sponsor
- Boehringer Ingelheim
Hepatitis A, Human Immunodeficiency Virus
Effectiveness of Booster With 1 or 2 Doses of HAV Vaccine Among HIV-infected Patients
Though HAV is mainly transmitted through the fecal-oral route, infection by sexual intercourse and blood transfusion is also possible.
- Conditions
- Hepatitis A, Human Immunodeficiency Virus, Vaccine Response Impaired
- Trial name
- NCT03855176
- Testing
- Vaqta Injectable Product
- Where
- Taiwan
- Volunteers
- 153 people
- Sponsor
- National Taiwan University Hospital
HIV, Mitochondrial Toxicity
NRTI-Sparing Pilot Study
This study will compare a nucleoside reverse transcriptase inhibitor-sparing (NRTI-sparing) regimen (Kaletra + nevirapine) to two nucleoside reverse transcriptase inhibitor-based regimens (Combivir + nevirapine and Combivir +…
- Trial name
- NCT00143689
- Testing
- lopinavir/ritonavir; nevirapine; Zidovudine; Lamivudine
- Where
- 4 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of British Columbia
Hepatitis C
Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection.
The aim of the study is to determine if treatment for recently acquired hepatitis C infection (with or without HIV coinfection) can be shortened when treating with the interferon-free therapy sofosbuvir/velpatasvir (SOF/VEL).
- Trial name
- REACT (NCT02625909)
- Testing
- SOF/VEL for 6 weeks, SOF/VEL for 12 weeks
- Where
- 25 sites in United States, Australia and 6 more
- Volunteers
- 222 people
- Sponsor
- Kirby Institute
Smoking Cessation, HIV Infections
Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV
The purpose of this two arm randomized clinical trial (RCT) is to test if a smoking cessation program called Quit for Life (QFL) which was developed by the investigators is effective for patients in China with HIV who smoke.
- Trial name
- QFL (NCT05020899)
- Testing
- Sessions with a trained counselor, Cell phone messages, Offered nicotine replacement therapy
- Where
- 2 sites in United States, China
- Volunteers
- 109 people
- Sponsor
- Boston Medical Center
HIV Infections, Fatigue
Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS
This study will determine whether armodafinil (Nuvigil), an FDA approved medication, is effective in reducing fatigue in adults with HIV/AIDS.
- Trial name
- NCT00737204
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- New York State Psychiatric Institute
HIV Infection, HIV Infections
Integration of Family Planning and HIV Services in Tanzania
HIV positive women and couples have broad reproductive health needs that are not always met within HIV services. The integration of family planning (FP) services into Tanzania's HIV Care and Treatment Clinics (CTC) will address…
- Trial name
- NCT00941876
- Testing
- Facilitated Referral
- Where
- Tanzania
- Volunteers
- 864 people
- Sponsor
- FHI 360
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Trimetrexate Plus Leucovorin in Children With Pneumocystis Carinii Pneumonia
To evaluate the safety and efficacy of trimetrexate glucuronate with leucovorin protection in pediatric patients with Pneumocystis carinii pneumonia (PCP) who are refractory to or have demonstrated severe or life-threatening…
- Trial name
- NCT00002317
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Sponsor
- U.S. Bioscience
Sarcoma
Valganciclovir in Treating Patients With Classic Non-HIV-Associated Kaposi's Sarcoma
RATIONALE: Herpesvirus is found in the lesions of most patients with Kaposi's sarcoma, and may have a role in causing Kaposi's sarcoma.
- Trial name
- NCT00096538
- Testing
- valganciclovir
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV Infections
Effects of Giving Interleukin-2 (IL-2) Plus Anti-HIV Therapy to HIV-Positive Patients With CD4 Cell Counts of at Least 350 Cells/mm3
The purpose of this study is to evaluate the safety and tolerability of giving IL-2 plus anti-HIV (antiretroviral) therapy to HIV-positive patients with CD4 cell counts (cells of the immune system that fight infection) of at…
- Trial name
- NCT00000948
- Testing
- Aldesleukin, ART
- Where
- 2 sites in Thailand
- Volunteers
- 72 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS, Gonorrhea
A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)
This study evaluates and compares two implementation strategies of an online HIV prevention intervention: Strategy 1 in which community-based organizations apply, and are selected, for funding to deliver Keep It Up! through…
- Conditions
- HIV/AIDS, Gonorrhea, Chlamydia
- Trial name
- NCT03896776
- Testing
- Keep It Up! 3.0
- Where
- United States
- Volunteers
- 2,249 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Social Harms in Substance Users in HIV Trials, Audio Computer Assisted Self-administered Questionnaire
Improving Identification of Social Harm Among Substance Abusers in HIV Trials
This two-phased project will develop a comprehensive, audio computer assisted self-administered interview social harm questionnaire (ACASI-SHQ) that will allow researchers to more easily identify and monitor social harms…
- Trial name
- NCT02148276
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Treatment Research Institute
HIV Infections, Non-Alcoholic Fatty Liver Disease
Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)
The purpose of this study was to evaluate the effects of semaglutide on intra-hepatic triglyceride (IHTG) content in people living with HIV (PLWH), central adiposity, insulin resistance or pre-diabetes, and hepatic steatosis.
- Trial name
- NCT04216589
- Testing
- Semaglutide
- Where
- 9 sites in United States, Brazil
- Volunteers
- 51 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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