Clinical trials: HIV Infections, completed
Hypertriglyceridemia, HIV Infections
Effect of Soluble Fiber on Hypertriglyceridemia and Immune Profile in HIV-positive Individuals.
The purpose of this study was to assess the effect of soluble fiber® (partially hydrolyzed guar gum) supplementation on hypertriglyceridemia and immune profile in HIV-positive individuals on HAART.
- Trial name
- NCT00540111
- Testing
- soluble fiber® (partially hydrolyzed guar gum)
- Volunteers
- 19 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
HIV-1-infection
Study of the Safety of Trogarzo™ Administered as an Undiluted "IV Push" or an Intramuscular Injection
This study is designed to assess the safety and pharmacokinetic profile of 800 mg Trogarzo once every two weeks administered via "IV Push" or intramuscular injection.
- Trial name
- NCT03913195
- Testing
- ibalizumab-uiyk
- Where
- 4 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- TaiMed Biologics Inc.
Tuberculosis, HIV Infections
Investigational Vaccine for the Prevention of Disseminated Tuberculosis in HIV Infected People
A significant number of HIV infected patients in Africa also have disseminated tuberculosis (infection throughout multiple organs). This type of tuberculosis is a significant cause of mortality in these patients.
- Trial name
- NCT00052195
- Testing
- SRL-172
- Where
- Tanzania
- Volunteers
- 1,975 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
HIV
Pharmacotherapy Follow-up in Older HIV-infected Patients
Cardiovascular diseases (CVD) are the main cause of death in Spain. In HIV patients, the uncontrolled viral replication, antiretroviral therapy (ART) and coinfections contribute to develop metabolic diseases and increase the…
- Trial name
- NCT02763995
- Testing
- Pharmaceutical care
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Elza Aparecida Machado Domingues
HIV Infections
Gut Microbiota Changes of HIV Patients Before and After One Year of ART
HIV infection leads to destruction of CD4+T cells in the gut-associated lymphoid tissue (GALT) and promotes a decline in mechanical barrier functions of the gut mucosa, and the subsequent translocation of microbial products from…
- Trial name
- NCT04297501
- Testing
- Antiretroviral Therapy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Mycobacterium Avium-Intracellulare Infection, HIV Infections
A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo
To compare the efficacy of clarithromycin/ethambutol with placebo or with rifabutin at two different doses in reducing colony-forming units (CFUs) by 2 or more logarithms in patients with Mycobacterium avium Complex bacteremia…
- Trial name
- NCT00002101
- Testing
- Ethambutol hydrochloride, Clarithromycin, Rifabutin
- Where
- 44 sites in United States
- Volunteers
- 450 people
- Sponsor
- Pharmacia
Hepatitis C, HIV
A Peer-based Mobile-health Intervention to Increase Access & Adherence to Hepatitis C Treatment & HIV Viral Suppression
The purpose of this study is to test an intervention designed to train persons who inject drugs (PWID) and are infected with hepatitis C (HCV) and HIV in communication skills to 1) promote new HCV treatment and care 2) risk…
- Conditions
- Hepatitis C, HIV, Risk Reduction Behavior
- Trial name
- HCV-TTP (NCT02772328)
- Testing
- Peer Mentor
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Transplantation, Systemic Lupus Erythematosus
Multicenter Trial Evaluating the Immunogenicity of HPV Vaccination in Girls on Immunosuppressive Therapy.
PRIMAVERA is a Phase IIa clinical trial, with the objective to assess the immunologic response to HPV vaccine in a population of immunocompromised girls.
- Conditions
- Transplantation, Systemic Lupus Erythematosus, Systemic Immune Disease
- Trial name
- PRIMAVERA (NCT01687192)
- Testing
- HPV prophylactic vaccine Gardasil
- Where
- 9 sites in France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Bordeaux
HIV Infections
A Study to Explore the Association Between Blood Pressure, HIV and Antiretroviral Therapy
The purpose of this study is to explore the association between blood pressure, HIV and/or its treatment in a cross sectional observational study.
- Trial name
- NCT00131807
- Testing
- Blood Pressure Measurement, Questionnaire
- Where
- United Kingdom
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Candidiasis, Oral, HIV Infections
A Comparison of SCH 56592 and Fluconazole in the Treatment of Oropharyngeal Candidiasis (OPC) in HIV-Positive Patients
The purpose of this study is to compare the safety and effectiveness of SCH 56592 with that of fluconazole in the treatment of OPC (a fungal infection of the throat) in HIV-positive patients.
- Trial name
- NCT00002399
- Testing
- Posaconazole, Fluconazole
- Where
- 53 sites in United States, Argentina and 16 more
- Volunteers
- 500 people
- Sponsor
- Schering-Plough
HIV Infections, Sexually Transmitted Diseases
Prevalence of HIV and Other Sexually Transmitted Infections Among Female Sex Workers and Miners in Honghe Prefecture, Yunnan Province, China
The purpose of this study is to collect data on the HIV strains currently circulating among female sex workers (FSWs) and their clients. In addition, this study will identify potential participants for future studies.
- Trial name
- NCT00278499
- Testing
- Cross-sectional surveys, Questionnaire/counseling
- Where
- 2 sites in China
- Volunteers
- 3,800 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Treatment of Hepatitis C
Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 8 Weeks in Subjects With Chronic Genotype 1 HCV and HIV-1 Co-infection
Target Population: Hepatitis C Treatment Naïve, non-cirrhotic, Chronic genotype 1 hepatitis C virus (HCV) infected adults that are co-infected with human immunodeficiency virus (HIV)-1and have HCV RNA < 6 x106 IU/mL Duration of…
- Trial name
- NCT02480387
- Testing
- Ledipasvir/Sofosbuvir FDC
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Peter J. Ruane, M.D., Inc.
HIV Infections
Comparison of Treatment Simplification by LPV/r vs Current Treatment Continuation in HIV-Infected Patients
The purpose of this study is to compare the efficacy and tolerance of a treatment simplification by a Lopinavir/ritonavir monotherapy versus continuation of current treatment in HIV-infected patients
- Trial name
- KALESOLO (NCT00140751)
- Testing
- Lopinavir/ritonavir (drug)
- Where
- 25 sites in France
- Volunteers
- 186 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
HIV Infections
Could Dietary Algae Affect Immunity and Viral Counts in People With HIV?
Drawing inferences from epidemiologic studies of HIV/AIDS as well well as cell culture and animal studies of HIV inhibition by algae, we propose algal consumption as one unifying characteristic of countries with anomalously low…
- Trial name
- HIV (NCT01195077)
- Testing
- seaweed, spirulina, seaweed + spirulina
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of South Carolina
HIV Infections
Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With Men
This study will evaluate the safety and efficacy of the human monoclonal antibody (mAb) VRC-HIVMAB060-00-AB (VRC01) in preventing HIV-1 infection among men and transgender (TG) persons who have sex with men, in North America…
- Trial name
- NCT02716675
- Testing
- VRC01
- Where
- 26 sites in United States, Brazil and 2 more
- Volunteers
- 2,699 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
IPV, HIV
Tu'Washindi RCT: Adolescent Girls in Kenya Taking Control of Their Health
This study will test the effectiveness of a youth-designed multilevel intervention, Tu'Washindi, to increase PrEP use and reduce intimate partner violence (IPV) among Kenyan AGYW and to identify implementation challenges and…
- Conditions
- IPV, HIV, PrEP
- Trial name
- NCT05599581
- Testing
- Tu'Washindi
- Where
- 2 sites in Kenya
- Volunteers
- 1,562 people, healthy volunteers welcome
- Sponsor
- RTI International
HIV, Stroke
Impact of HIV-infection on Clinical Characteristics and Outcomes on Stroke in Uganda
The investigators will recruit participants from three tertiary care hospitals in Uganda into an observational cohort study of people living with HIV/AIDS (PLWHA) and HIV-uninfected persons matched for gender and residency…
- Trial name
- NCT03072212
- Testing
- Observational study
- Where
- Uganda
- Volunteers
- 200 people
- Sponsor
- Mbarara University of Science and Technology
HIV Infections
Phase I Trial of an Intervention to Increase Condom Use by HIV-Discordant Couples
To assess the acceptability of and participation in a group counseling intervention, including an assessment of willingness to disclose serostatus to a regular sexual partner and the willingness of that partner to participate.
- Trial name
- NCT00000928
- Testing
- Group counseling intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis C, Liver Cirrhoses
Simplified Monitoring Myanmar SM2 Study
The study will evaluate the proportion of patients with undetectable HCV RNA at 12 weeks post-treatment (SVR12) following a course of DAA therapy delivered using a simplified schedule of safety and virological monitoring.
- Conditions
- Hepatitis C, Liver Cirrhoses, Liver Inflammation, HIV Infections
- Trial name
- SM2 (NCT04113629)
- Testing
- HCV point of care machine
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Kirby Institute
Acquired Immunodeficiency Syndrome, HIV Infection
Home Treatment of HIV-Infected Patients With Interleukin-2 With or Without a Tumor Necrosis Factor Antagonist
Patients enrolled in NIH protocol 95-I-0133 at the Clinical Center may participate in an extension phase of this study in which the drug prednisone will be eliminated from the treatment regimen.
- Trial name
- NCT00001475
- Testing
- IL-2 plus Anti-TNF or Thalidomide
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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