Clinical trials: HIV Infections, completed
HIV Infections
Effects of Tipranavir/Ritonavir on the Pharmacokinetic Characteristics of Triple Drug Nucleoside and Non-nucleoside Reverse Transcriptase Inhibitor Therapy in HIV-1-infected Subjects
Primary: Sequentially determine the effects of three dose combinations of tipranavir (TPV) / ritonavir (RTV) (administered b.i.d.), TPV 1250 mg/RTV 100 mg vs. TPV 750 mg/RTV 100 mg vs.
- Trial name
- NCT02251223
- Testing
- Tipranavir low dose, Tipranavir medium dose, Tipranavir high dose
- Volunteers
- 208 people
- Sponsor
- Boehringer Ingelheim
HIV Infections
No Excuses/Sin Buscar Excusas Intervention to Reduce Latino Men's HIV Risks
The overall goal of this study is to develop and evaluate a brief, video-based, group-level intervention designed to reduce sexual risk taking among culturally diverse English- and Spanish-speaking Latino men who have sex with…
- Trial name
- NCT00690690
- Testing
- Video (group-delivered video-based intervention), HCT
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Patient Adherence, HIV
Text Messaging Intervention to Improve ART Adherence Among HIV-positive Youth
The purpose of the proposed study is to test SMS (short message service) text messaging technology to improve medication adherence among youth living with HIV (YLH).
- Trial name
- TXTXT (NCT01354210)
- Testing
- SMS Text Message Reminder
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Medication Adherence, HIV Prevention
PrEP Affect Regulation Treatment Innovation
This multi-site randomized controlled trial enrolling sexual minority men who use stimulants and are currently taking pre-exposure prophylaxis (PrEP).
- Conditions
- Medication Adherence, HIV Prevention, Stimulant Use
- Trial name
- PARTI (NCT04899024)
- Testing
- PARTI, Attention-Control, Contingency Management for PrEP Adherence
- Where
- 2 sites in United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Florida International University
HIV Infections
Study of Bictegravir/Emtricitavine/Tenofovir Alafenamide in HIV-1 Infected naïve Patients Using Test and Treat Stategy Rapid-initiation Model of Care: BIC-NOW Clinical Trial (BIC-NOW)
The goal of this study is to analyze in treatment-naïve HIV patients the antiviral activity, using a test and treat strategy, in real life of BIC/FTC/TAF.
- Trial name
- BIC-NOW (NCT06177574)
- Testing
- BIC/FTC/TAF
- Where
- 15 sites in Spain
- Volunteers
- 208 people
- Sponsor
- Carmen Hidalgo Tenorio
HIV/AIDS, Substance Use Disorders
HIV+ Substance Users Released From Jail
The long-term goal of this project is to improve HIV and substance use outcomes and reduce recidivism for HIV+ substance users released from jail.
- Trial name
- NCT03834779
- Testing
- DOORS-CHW Intervention
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Texas Southwestern Medical Center
HIV Infections, Acquired Immunodeficiency Syndrome
Vicriviroc in HIV(R5/X4)-Treatment Experienced Subjects (Study P05057AM5)(COMPLETED)
Vicriviroc (vye-kri-VYE-rock) is an investigational drug (not yet approved by Government Regulatory Authorities for commercial use) that belongs to a new class of drugs, called CCR5 receptor blockers.
- Trial name
- NCT00551330
- Testing
- Vicriviroc
- Volunteers
- 111 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV
Safety and Immune Response to a Prime-Boost Vaccination Schedule in HIV-infected Patients
Study Design: This is a Phase I, randomized, placebo-controlled, double-blinded study to examine safety, tolerability and immune response of a prime-boost vaccination regimen for treatment of HIV infection.
- Trial name
- NCT00270465
- Testing
- VRC-HIVDNA016-00-VP, VRC-HIVADV014-00-VP
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Alcohol and Drug Abuse
Reducing Offenders' HIV Risk: MI Enhanced Case Management With Drug-Free Housing
The goal of the study is to see if a Motivational Interviewing Case Management (MICM) intervention will improve outcomes for respondents who are on probation or parole, at risk for HIV and have recently entered a Sober Living…
- Trial name
- NCT01977092
- Testing
- Motivational interviewing case management, Resource referrals
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Public Health Institute, California
HIV
Predicting Treatment and Care Difficulties Among HIV Infected Patients
Much of HIV is related to behaviour: sexual risk taking, late diagnosis, adherence to antiretroviral therapy, follow up, disclosure of one's HIV status.
- Trial name
- PREDIVI (NCT02900599)
- Testing
- Observationnal (no intervention)
- Volunteers
- 111 people
- Sponsor
- Centre Hospitalier de Cayenne
HIV Infection, Erythrocyte Glutathione Deficiency
Role of HIV on Glutathione Synthesis and Oxidative Stress
HIV infection is associated the development of increased oxidative stress and deficiency of glutathione (GSH), the dominant endogenous antioxidant protein, but the underlying mechanisms contributing to GSH deficiency are hitherto…
- Trial name
- NCT01355198
- Testing
- Cysteine (as n-acetylcysteine) and glycine, Cysteine/glycine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Alcohol Drinking, Alcohol Use Norms
Formative Phase of Reducing Hazardous Alcohol Use & HIV Viral Load
This study is the Formative Phase of a larger study; once this phase is completed, enrollment into the randomized controlled trial (RCT Phase) will begin.
- Conditions
- Alcohol Drinking, Alcohol Use Norms, Alcohol Use Among ART Clients
- Trial name
- F-REDART (NCT02153216)
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infection, Drug Use
Linking Infectious and Narcology Care in Russia
The purpose of this study is to implement and assess a behavioral and structural intervention in Russia designed to support and motivate HIV-infected narcology heroin dependent patients (i.e., IDUs) to engage (i.e., initiate and…
- Trial name
- LINC (NCT01612455)
- Testing
- LINC Case Management
- Where
- 3 sites in Russia
- Volunteers
- 349 people
- Sponsor
- Boston Medical Center
HIV Infections, Sexually Transmitted Diseases
Development and Evaluation of an HIV, STD, and Pregnancy Prevention Program for Middle School Students
This study will develop and evaluate a school-based HIV, STD, and pregnancy prevention program for 7th and 8th grade middle school students.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy
- Trial name
- NCT00161382
- Testing
- HIV, STD, and pregnancy prevention curriculum, Standard sexual education curriculum
- Where
- United States
- Volunteers
- 3,007 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cryptosporidiosis, HIV Infections
A Study of Spiramycin in the Treatment of Patients With AIDS-Related Diarrhea
To determine the safety and effectiveness of intravenous spiramycin in patients with AIDS-related cryptosporidial diarrhea. Spiramycin, a macrolide antibiotic, has been studied in the United States for the treatment of…
- Trial name
- NCT00000980
- Testing
- Spiramycin
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Rhone-Poulenc Rorer
Human Immunodeficiency Virus
Improving Outcomes in HIV Patients Using Mobile Phone Based Interactive Software Support
Current estimates point towards a huge increase in the number of people that are eligible to start ART in Uganda and globally. As many of the newly eligible patients are largely asymptomatic, there are concerns about adherence…
- Trial name
- Callforlife (NCT02953080)
- Testing
- Call for life mHealth adherence support
- Where
- Uganda
- Volunteers
- 600 people
- Sponsor
- Makerere University
HIV Infections
Evaluation of Low-dose Darunavir in a Switch Study
This is a switch study to assess the non-inferiority (in terms of efficacy and safety) of darunavir (boosted with ritonavir, DRV/r 400mg/100mg daily) when compared with lopinavir (boosted with ritonavir, LPV/r total dose…
- Trial name
- DRV (NCT02671383)
- Testing
- Darunavir, Lopinavir
- Where
- South Africa
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Willem Daniel Francois Venter
HIV
Culturally Sensitive Intervention to Improve Retention in HIV Care for Latino MSM
The goal of this proposal is to culturally adapt and tailor an existing, theory-based intervention, using state-of-the-art methods designed to maximize cultural sensitivity, feasibility and acceptability to HIV+ Latino MSM, and…
- Trial name
- PODER (NCT01457066)
- Testing
- Peer Navigator Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of California, Los Angeles
HIV
A Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRCHIVMAB0115-00-AB (VRC01.23LS), Administered Intravenously or Subcutaneously to Healthy Adults
Background: HIV causes AIDS, a serious disease that can lead to fatal infections. HIV infection can be controlled but not cured, nor is there a vaccine to prevent it.
- Trial name
- NCT05627258
- Testing
- VRC-HIVMAB0115-00-AB
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Get Connected Efficacy Trial
Get Connected (GC) is an online brief intervention that employs individual and systems-level tailoring technology to reduce barriers to HIV prevention care (e.g., HIV/STI testing, PrEP) for YMSM.
- Trial name
- NCT03132415
- Testing
- Get Connected, HIV Test Locator
- Where
- 3 sites in United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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