Clinical trials: HIV Primary Infection
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
HIV Infections, Sexually Transmitted Diseases
Parents Matter!: Interventions to Promote Effective Parent-Child Communication
Parents Matter is a community-based project whose goal it is to develop and test an intervention designed to promote effective parent-child communication about sexuality in order to promote sexual health among adolescents.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy
- Trial name
- NCT00137943
- Testing
- Full Parent communication intervention, Brief Parent Communication Intervention, Control Parent Intervention
- Where
- 3 sites in United States
- Volunteers
- 2,210 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV, Buprenorphine
Integrating Buprenorphine Into the SFGH AIDS Program
The purpose of this study is to assess the feasibility, cost, and effectiveness of a model of care designed to integrate buprenorphine treatment for opioid dependence into the HIV primary care clinics at the UCSF Positive Health…
- Conditions
- HIV, Buprenorphine, Opioid Dependence
- Trial name
- BHIVES-SF (NCT00263458)
- Testing
- Integrated office-based buprenorphine treatment for opioid dependence in an HIV primary care setting
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of California, San Francisco
Chronic Myeloproliferative Disorders, Leukemia
Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone
RATIONALE: Gathering information about how often methemoglobinemia occurs in young patients receiving dapsone for hematologic cancer or aplastic anemia may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00993694
- Testing
- chemotherapy, dapsone, medical chart review
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Vanderbilt University
HIV Infection
Primary Resistance in HIV Patients in Colombia
The investigators' main objective is to determine the prevalence of pre-treatment of resistance-associated mutations (RAMs) in a naïve and recently diagnosed HIV infection in 18 centers from 12 cities in Colombia.
- Trial name
- NCT03957369
- Testing
- HIV-1 plasma RNA Genotyping secuencing by Sanger technique, HIV-1 plasma RNA Genotyping secuencing by Ultra-deep sequencing technique
- Where
- Colombia
- Volunteers
- 527 people
- Sponsor
- Fundacion REVIVA, Red de VIH del Valle del Cauca
HIV Infection
MAPS PrEP Van Study
For this study the investigators aim to see if giving participants an oral HIV prevention medication on a medical van, is a good option of care for individuals who inject drugs and/or are sexually active and therefore at a higher…
- Trial name
- MAPS PrEP (NCT06908252)
- Testing
- Pre-Exposure Prophylaxis (PrEP)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV-1-infection
An HIV Vaccine Trial in Individuals Who Started ART During Primary or Chronic Infection
EVHA T01 is an international, phase I/II, multicentre, multi-stage, double-blind study that will evaluate at least three experimental arms compared to placebo control in HIV-1 infected participants to see if one or more has a…
- Trial name
- EHVAT01 (NCT02972450)
- Testing
- GTU-MultiHIV B-clade vaccine + MVA HIV-B HIV vaccine, GTU-MultiHIV B-clade vaccine + MVA HIV-B HIV vaccine+ Vedolizumab, Vedolizumab 300 MG [Entyvio]
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 1 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Primary Aldosteronism
Diagnosis of Primary Aldosteronism: Comparison of Post Captopril Active Renin Concentration and Plasma Renin Activity
Background: The most common pharmacologic test for diagnosis of primary aldosteronism (PA) is administration of captopril to examine whether abnormal aldosterone to plasma rennin activity (PRA)(ARR) persists, although active…
- Trial name
- NCT00917345
- Testing
- captopril test
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Kaposi Sarcoma, KSHV Associated Multicentric Castleman Disease
Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis
Background: Some people with human immunodeficiency virus (HIV) are on antiretroviral therapy (ART). Their cells have shown to age faster than expected.
- Conditions
- Kaposi Sarcoma, KSHV Associated Multicentric Castleman Disease, Primary Effusion Lymphoma, IL-6 Related KSHV Associated Cytokine Syndrome
- Trial name
- NCT04742387
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute (NCI)
HIV, AIDS
Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care
To determine the efficacy of an algorithm designed to recommend smoking cessation-related pharmacotherapy options to the primary care providers of smokers living with HIV/AIDS.
- Conditions
- HIV, AIDS, Smoking Cessation
- Trial name
- NCT03670316
- Testing
- Algorithm Treatment, Quitline only
- Where
- United States
- Volunteers
- 371 people
- Sponsor
- University of Alabama at Birmingham
Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary
Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as topotecan, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Leukemia, Lymphoma
- Trial name
- NCT00112619
- Testing
- topotecan hydrochloride
- Where
- 11 sites in United States
- Volunteers
- 19 people
- Sponsor
- Pediatric Brain Tumor Consortium
Hiv, AIDS
The Influence of Primary HIV-1 Drug Resistance Mutations on Immune Reconstruction in PLWH
Since the reasons for differential immune reconstitution in HIV-infected patients are still not fully understood, we considered it reasonable to investigate whether the presence of primary HIV drug resistance mutations could be…
- Conditions
- Hiv, AIDS, CD4 Deficiency, ART
- Trial name
- NCT06044792
- Testing
- differences in CD4 reconstruction
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Human Immunodeficiency Virus (HIV), Sexually Transmitted Disease (STD)
Steering Together in a New Direction: Reducing the Risk of HIV/STD Among African American Men
African American men have by far the highest rates of HIV in the US, but there are few randomized controlled trials (RCTs) of interventions to dissuade heterosexually active African American men from engaging sexual risk…
- Trial name
- STAND (NCT02572401)
- Testing
- STAND HIV Risk Reduction Intervention, Text Messaging Intervention
- Where
- United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hiv
Innovative Strategies to Increase ART Initiation and Viral Suppression Among HIV-positive Men in Malawi
Men in Sub-Saharan Africa are less likely to test for HIV, initiate ART, and more likely to initiate ART at later stages of disease.
- Trial name
- NCT04878601
- Testing
- Home-Based ART, Facility-Based ART
- Where
- Malawi
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tuberculosis
Utility of Sputum Induction and Novel Technologies to Improve TB Diagnosis in a High HIV Prevalence Primary Care Setting
This study will investigate the benefit of using Sputum induction for TB diagnosis in a primary care clinic for adult TB suspects that are either unable to produce a sputum sample (sputum scarce) or on initial diagnostic work-up…
- Trial name
- SINET (NCT01545661)
- Testing
- Sputum induction, standard routine expectorated sputum
- Where
- South Africa
- Volunteers
- 517 people
- Sponsor
- University of Cape Town
HIV Infection Primary
Intervening With Haitian Immigrants in the U.S. to Improve HIV Outcomes
The goal of this clinical trial is to test a culturally tailored engagement and retention intervention for Haitian Immigrants Living With HIV (HILWH).
- Trial name
- NCT05947266
- Testing
- an adaptation of the iENGAGE
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Florida International University
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial
RATIONALE: Providing information that is tailored to answer patients' questions about clinical trials may help patients with cancer decide to enroll in a clinical trial.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00750009
- Testing
- educational intervention
- Where
- 4 sites in United States
- Volunteers
- 583 people
- Sponsor
- Case Comprehensive Cancer Center
Monotherapy, Dolutegravir
Early Simplified: A Trial to Compare the Efficacy of Standard of Care Combination Antiretroviral Therapy With a Simplified Dolutegravir Monotherapy in Patients With a Primary HIV-1 Infection
Long term toxicity of combination antiretroviral therapy (cART) is a substantial contributor to morbidity and mortality in chronically infected HIV positive individuals.
- Conditions
- Monotherapy, Dolutegravir, Primary HIV Infection, Treatment Efficacy
- Trial name
- NCT02551523
- Testing
- Dolutegravir, Standard of care combinational antiretroviral therapy
- Where
- Switzerland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hiv
Identifying Efficient Linkage Strategies for Men
HIV self-testing (HIVST) has been found to be a highly acceptable approach for men to learn of their HIV status and has resulted in increased testing uptake.
- Trial name
- IDEaL (NCT05137210)
- Testing
- Male Counseling and Facility Navigation, Home-Based ART Initiation and Facility Navigation, Stepped Intervention
- Where
- Malawi
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV, HBV (Hepatitis B Virus)
HIV/HBV/HCV Triple Screening in Primary Care
Design: This will be a within-subjects repeated-measures design, testing an electronic medical record pop-up alert linked to order panels for screening blood tests for human immunodeficiency virus (HIV), hepatitis B virus (HBV)…
- Conditions
- HIV, HBV (Hepatitis B Virus), HCV
- Trial name
- NCT07031219
- Testing
- electronic medical record alert linked to orders
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center