Clinical trials: HIV Treatment Adherence
Adherence, Patient, HIV/AIDS
Group Clinical Visit Adherence Intervention for HIV+ Women of Color
The investigators will conduct a pilot randomized controlled trial (RCT) of Sisters-GPS with HIV-positive women of color with suboptimal ARV adherence and detectable HIV viral loads (VL).
- Conditions
- Adherence, Patient, HIV/AIDS, Group Meetings
- Trial name
- NCT03109743
- Testing
- Sisters-GPS: Group Clinical Visits, Control: One-on-one Adherence Counseling
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
HIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health
Prevention of Mother-to-child Transmission (PMTCT) Among Women Experiencing Depression in Malawi
Prevention of mother-to-child transmission (PMTCT) of HIV virtually eliminates transmission of HIV from mothers to their infants.
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health, Depression During Pregnancy, PMTCT
- Trial name
- NCT06659315
- Testing
- Couples Problem Solving Therapy
- Where
- Malawi
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
HIV Infection
Antiretroviral Speed Access Program
Migrant populations represent an increasing proportion of newly referred people living with HIV in Canada, particularly in Quebec.
- Trial name
- ASAP (NCT04897243)
- Testing
- Biktarvy, Patient Experience
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Dr. Bertrand Lebouche
HIV/AIDS
Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients
The overall aim of this program of research is to test a newly developed intervention, Acceptance-Based Behavior Therapy (ABBT), to improve HIV patients' commitment to medical care.
- Trial name
- NCT04201288
- Testing
- Acceptance-Based Behavior Therapy (ABBT), Enhanced-Treatment-as-Usual (ETAU)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Brown University
Multi Drug Resistant Tuberculosis, HIV Infections
An Adaptive Randomized Controlled Trial
This is a prospective, adaptive, randomized controlled trial comparing the effectiveness of 4 intervention arms on a combined endpoint in adults with confirmed MDR-TB HIV initiating Bedaquiline-containing MDR-TB treatment…
- Trial name
- ADAP-TIV (NCT05633056)
- Testing
- Adherence support intevention
- Where
- South Africa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV (Human Immunodeficiency Virus)
Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy Phase II
This protocol describes a 2-arm cluster, randomized controlled trial designed to test the effectiveness of a conditional cash transfer on viral suppression at 12 months post-ART initiation among PHWHIV who have initiated ART…
- Trial name
- Afya 2 Phase2 (NCT04201353)
- Testing
- Conditional Cash Transfer
- Where
- Tanzania
- Volunteers
- 1,984 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Adult, HIV Infections
Adherence Toolkit for Managing Nonadherence to HIV Medications in Indonesia
The goal of this usability study and a cluster randomised controlled trial is to investigate the effectiveness of an adherence toolkit as a decision support tool to improve adherence to antiretroviral therapy.
- Trial name
- NCT05996081
- Testing
- Adherence toolkit
- Where
- Indonesia
- Volunteers
- 400 people
- Sponsor
- University of Groningen
HIV, Patient Acceptance of Health Care
Network Supported Engagement In HIV Care
The Network Supported Engagement in Care (NSEC) intervention is a brief, theory based and culturally sensitive intervention designed to capitalize on organic yet underutilized social support networks in the lives of young black…
- Trial name
- NSEC (NCT01726712)
- Testing
- Supportive Care
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Viral Resistance, Treatment Failure
Virologic Treatment Failure and Drug Resistance in HIV-infected Kenyan Children (RESPECT)
The primary objective of this study is to use a well-characterized pediatric AMPATH cohort, with detailed medication-taking, drug level, and clinical data, to longitudinally evaluate treatment failure and drug resistance to…
- Trial name
- RESPECT (NCT03120065)
- Testing
- Electronic Dose Monitoring (MEMS)
- Where
- Kenya
- Volunteers
- 499 people
- Sponsor
- Rachel Vreeman, MD, MS
Hiv, Adherence, Medication
Using Smart Phone Technology to Support HIV Medication Refill Adherence in Virginia
The purpose of this study is to pilot a mobile health intervention, originally designed for HIV retention in care, for use in aiding patients with medication refills.
- Trial name
- NCT03876626
- Testing
- PositiveLinks RX Mobile App, PositiveLinks RX Portal
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Virginia
HIV Infections
Supportive Therapy for Adherence to ART(STAART)
The purpose of this study is to determine whether a psycho-educational intervention can help people living with HIV handle the changes of treatment adherence.
- Trial name
- NCT00212940
- Testing
- Supportive Therapy for Adherence to ART (behavior)
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- Ottawa Hospital Research Institute
Adherence, Patient, TB
Leveraging mHealth to Enable and Adapt CHW Strategies to Improve TB/HIV Patient Outcomes in SA
mHealth solutions designed to support affordable human resources for health, such as community health workers (CHWs), offer the opportunity to reimagine a patient-centered, system-level solution that may radically change care…
- Conditions
- Adherence, Patient, TB, HIV/AIDS, Care Coordination
- Trial name
- LEAP-TB-SA (NCT04298905)
- Testing
- CHW mHealth patient intervention for trigger escalation
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Johns Hopkins University
HIV-infection/Aids
The Effectiveness of a Mobile Interactive Supervised Therapy (MIST) Intervention for Improving Adherence to HIV Medication
A total of 40 HIV infected patients will be randomly assigned into intervention or control group. Participants in the intervention group will use an smart phone application for two months.
- Trial name
- NCT03794648
- Testing
- Mobile Interactive Supervised Therapy (MIST)
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
HIV Antiretroviral Therapy (ART) Adherence
Implementation and Effects of Nishauri on HIV Treatment Outcomes Among Men
About 1.3 million people in Kenya are living with HIV, and Homa Bay County has the highest rate in the country. Even though HIV treatment has improved, many men still face challenges staying in care, taking their medicine, and…
- Trial name
- Nishauri I (NCT07116538)
- Testing
- Nishauri mHealth Intervention
- Where
- Kenya
- Volunteers
- 347 people
- Sponsor
- Maseno University
Pain Interference, Depression
Treating Chronic Pain and Depression in HIV+ Patients in Primary Care Settings
The purpose of this study is to determine whether participation in the study intervention, which involves collaboration between the study interventionist and the participant's primary care physician, will reduce symptoms of pain…
- Conditions
- Pain Interference, Depression, Antiretroviral Adherence
- Trial name
- HIVPASS (NCT01735708)
- Testing
- HIVPASS, Health Education
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Butler Hospital
HIV Infections, Lipodystrophy
Perceived Changes in Body Build and Image in Patients Who Are Now Taking or Recently Have Stopped Taking Anti-HIV Drugs
The purpose of this study is to learn how changes in body build affect the lives of people taking anti-HIV medications. By learning this, a set of questions can be created to help understand how changes in body build and image…
- Trial name
- NCT00006290
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV-1-infection
Group-Based Intervention to Improve Mental Health and Adherence Among Youth Living With HIV in Low Resource Settings
IMPAACT 2016 was a multi-site, two-arm, individually randomized, controlled study to evaluate whether an Indigenous Leader Outreach Model (ILOM) of trauma-informed cognitive behavioral therapy (TI-CBT) delivered by Indigenous…
- Trial name
- NCT04024488
- Testing
- Youth TI-CBT Intervention Arm, Youth Discussion Control Arm, Caregiver TI-CBT Intervention Arm
- Where
- 8 sites in Botswana, Malawi and 2 more
- Volunteers
- 484 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
PTSD, Hiv
CPT-L to Improve Outcomes for Individuals With HIV and PTSD
This study plans to adapt and examine the acceptability and feasibility of an evidence-based PTSD treatment that has reduced other HIV transmission behavior (e.g., sexual risk), Cognitive Processing Therapy (CPT), at an HIV…
- Trial name
- NCT05275842
- Testing
- Cognitive Processing Therapy- Lifesteps (CPT-L), Lifesteps
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Medical University of South Carolina
Economic Hardship, Condomless Sex
Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)
The study team will conduct a two-group study to examine the efficacy of implementing a combination intervention to improve economic stability and HIV preventive behaviors. The team will enroll approximately 500 young adults.
- Conditions
- Economic Hardship, Condomless Sex, Utilization, Health Care
- Trial name
- ENSPIRE (NCT06096324)
- Testing
- Job announcements plus HIV prevention text messages, educational sessions, economic resources, and mentoring., Job announcements
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill