Clinical trials: HIV Treatment Adherence
Depressive Symptoms, HIV Infections
Depression and ART Adherence in HIV+ Latinos
The current HIV treatment adherence project was designed to adapt culturally and then pilot test an empirically supported cognitive-behavioral therapy program for adherence and symptoms of depression (CBT-AD)with HIV+ Latinos…
- Trial name
- NCT01411839
- Testing
- Cognitive-Behavioral Therapy (CBT-AD)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
HIV Infections
Effect of Medication Diaries on Adherence to Highly Active Antiretroviral Drugs Among HIV-1 Infected Kenyan Children
Following significant reduction in antiretroviral drug prices over the past two years, more HIV-1 infected African adults and children are gaining access to treatment.
- Trial name
- NCT00194545
- Testing
- Medication diaries
- Where
- Kenya
- Volunteers
- 100 people
- Sponsor
- University of Washington
HIV Infections, Adherence
Adherence-Suppression-Resistance Relationships for Atripla Compared to Historical Antiretroviral Regimens
The study is recruiting 50 patients initiating or switching to Atripla and comparing them to 250 individuals previously followed in a prospective study of HIV+ low income individuals recruited from homeless shelters, single room…
- Trial name
- NCT01006005
- Volunteers
- 51 people
- Sponsor
- University of California, San Francisco
HIV, Tuberculosis
ENhance Initiation and Retention in Isoniazid Preventive Therapy (IPT) Care for HIV Study (ENRICH Study)
The purpose of the ENRICH study is to evaluate a combination intervention package (CIP) designed to improve implementation of Isoniazid Preventive Therapy (IPT) among people living with HIV (PLWH) in Ethiopia.
- Trial name
- ENRICH (NCT01926379)
- Testing
- Combination intervention components, Isoniazid Prevention Therapy
- Where
- 10 sites in Ethiopia
- Volunteers
- 338 people
- Sponsor
- Columbia University
HIV Infections
Telephone Support to Improve Adherence to Anti-HIV Medications
This study tested a system of nursing telephone support to determine if it improves adherence to antiretroviral therapy (ART) in at-risk, treatment-experienced people.
- Trial name
- NCT00988442
- Testing
- Enhanced nursing telephone support, Standard care
- Where
- 16 sites in United States
- Volunteers
- 59 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Infections, Acquired Immunodeficiency Syndrome
Effectiveness of Enhanced Counseling and Observed Therapy on Antiretroviral Adherence in People With HIV
This study will compare the effectiveness of enhanced counseling alone versus enhanced counseling combined with observed therapy at improving medication adherence in people with HIV.
- Trial name
- NCT00602758
- Testing
- Motivational interviewing with cognitive behavioral therapy, Modified directly observed therapy
- Where
- 4 sites in United States
- Volunteers
- 252 people
- Sponsor
- University of Missouri, Kansas City
HIV, Alcohol Use
Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings
Alcohol use is increasingly recognized as a key factor in morbidity and mortality among HIV-positive individuals and represents an important public health concern, given its associations with medication non-adherence, increases…
- Conditions
- HIV, Alcohol Use, Medication Adherence
- Trial name
- PLUS (NCT02390908)
- Testing
- Immediate PLUS intervention, Wait-list PLUS intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
HIV Infections
Adherence Intervention for People With Low-literacy
Consistent adherence to antiretroviral therapy is necessary for treatment success. People with poor health literacy skills experience considerable difficulty adhering to their medications.
- Trial name
- NCT01061762
- Testing
- Stick To It, Standard medication adherence counseling, Health Counseling
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Connecticut
Medication Adherence, HIV Prevention
PrEP Affect Regulation Treatment Innovation
This multi-site randomized controlled trial enrolling sexual minority men who use stimulants and are currently taking pre-exposure prophylaxis (PrEP).
- Conditions
- Medication Adherence, HIV Prevention, Stimulant Use
- Trial name
- PARTI (NCT04899024)
- Testing
- PARTI, Attention-Control, Contingency Management for PrEP Adherence
- Where
- 2 sites in United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Florida International University
HIV Infections, Substance Use Disorders
Couples ART Adherence Intervention for PWID in Kazakhstan
The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression.
- Trial name
- NCT03555396
- Testing
- SMART Couples 2, Standard of Care
- Where
- Kazakhstan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV, Tuberculosis
Evaluation of South Africa's National Adherence Strategy
NOTE THAT THE STUDY IS LED BY SOUTH AFRICA NATIONAL DEPARTMENT OF HEALTH AND WORLD BANK WITH SUPPORT FROM BOSTON UNIVERSITY. The South Africa National Department of Health (NDOH) intends to launch its newly developed National…
- Conditions
- HIV, Tuberculosis, Diabetes, Hypertension
- Trial name
- ENHANCE (NCT02536768)
- Testing
- Minimum package of interventions to improve ART adherence
- Where
- South Africa
- Volunteers
- 8,020 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV Infection
Typology of Adherence in Adolescents: Phase II
A number of factors influence HIV-positive adolescents' acceptance of and willingness to continue taking anti-HIV medicines. These factors include mental health and substance abuse issues, barriers such as lack of medical…
- Trial name
- NCT00106678
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 1,200 people
- Sponsor
- University of North Carolina, Chapel Hill
Human Immunodeficiency Virus Infection (HIV), HIV-1 Infection in Adults
Long-Term Real-World Evidence Study to Evaluate Effectiveness, Persistence, Adherence, Safety and Tolerability of Long-acting Cabotegravir Plus Rilpivirine.
The RELATIVITY study is a nationwide, multicenter, ambispective observational cohort evaluating the long-term effectiveness, safety, persistence, and tolerability of long-acting injectable cabotegravir plus rilpivirine (CAB+RPV…
- Trial name
- NCT07703748
- Where
- Spain
- Volunteers
- 3,346 people
- Sponsor
- FUNDACIÓN HOSPITAL UNIVERSITARIO INFANTA LEONOR Y DEL HOSPITAL UNIVERSITARIO DEL SURESTE
HIV-1
PI or NNRTI as First-line Treatment of HIV in West Africa - the PIONA Trial
BACKGROUND: Since 1996 the combination of three or more drugs has been the mainstay of human immunodeficiency virus (HIV) treatment.
- Trial name
- PIONA (NCT01192035)
- Testing
- Efavirenz or Nevirapine, Ritonavir-boosted lopinavir
- Where
- Guinea-Bissau
- Volunteers
- 400 people
- Sponsor
- University of Aarhus
HIV, Hepatitis C
Intervention to Improve HCV Treatment Uptake and Adherence in HIV/HCV Coinfection
End-stage liver disease, predominantly due to hepatitis C virus (HCV) infection, is one of the leading causes of death in person living with HIV infection.
- Conditions
- HIV, Hepatitis C, Co-Infection
- Trial name
- NCT02294136
- Testing
- Prep-C, Educational Control
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV/AIDS, Adherence, Medication
Quantification of Tenofovir Alafenamide Adherence (QUANTI-TAF)
This study is being done to evaluate the relationship between adherence to antiretroviral therapy (ART) and HIV drug concentrations in persons living with HIV (PLWH) that are taking tenofovir alafenamide (TAF).
- Trial name
- NCT04065347
- Testing
- Digital Pill
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver
Adherence, Medication, Adolescent Behavior
Youth-focused Strategies to Promote Adherence to Pre-exposure Prophylaxis Among Youth At-risk for HIV in Thailand
A randomized controlled clinical trial looking at the effect of use of a mobile phone application in addition to standard care compared to standard care alone at a youth-friendly clinic in young men who have sex with men and…
- Conditions
- Adherence, Medication, Adolescent Behavior, HIV Prevention, Sexual Health
- Trial name
- YouthPrEP (NCT03778892)
- Testing
- 'Project Raincoat' Mobile Phone Application
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
HIV, Adherence
Evaluation of a Computer-Based System Using Cell Phones for HIV People in Peru
The investigators propose to develop and evaluate a computer-based intervention using cell phones to enhance adherence to antiretroviral treatment (ART) and support of HIV transmission risk-reduction among adult HIV-positive…
- Conditions
- HIV, Adherence, Sexual Behavior, HIV Infections
- Trial name
- Cell-POS (NCT01118767)
- Testing
- Cell phone intervention
- Where
- 2 sites in Peru
- Volunteers
- 210 people
- Sponsor
- Universidad Peruana Cayetano Heredia
HIV Infections
Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings
This study compared 3 different three-drug combinations in HIV infected individuals starting their first HIV treatment regimens.
- Trial name
- PEARLS (NCT00084136)
- Testing
- Atazanavir, Didanosine (enteric-coated), Efavirenz
- Where
- 42 sites in United States, Brazil and 7 more
- Volunteers
- 1,571 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV, Opiate Dependence
Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
This study will test whether contingency management (monetary vouchers contingent on abstinence from drugs) that reinforces one behavior (achieving abstinence from drugs) leads to improved outcomes in other related behaviors…
- Trial name
- Project FIRST (NCT01376570)
- Testing
- Abstinence-reinforcing contingency management intervention, Performance Feedback intervention
- Where
- 3 sites in United States
- Volunteers
- 242 people
- Sponsor
- Albert Einstein College of Medicine