Clinical trials: HIV Treatment Adherence
Human Immunodeficiency Virus, Stigma, Social
Mitigating Sexual Stigma Within Healthcare Interactions Improve Engagement of MSM in HIV Prevention
The purpose of this study is to explore drivers and mitigators of anal sex stigma in healthcare, and then to develop and pilot an intervention for health workers that mitigates the deterrent effects of this stigma on the…
- Conditions
- Human Immunodeficiency Virus, Stigma, Social, Patient Engagement
- Trial name
- NCT04779736
- Testing
- A set of implementation strategies to reduce sexual stigma
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
HIV Care Loss to Followup, HIV Antiretroviral Therapy (ART) Adherence
Developing and Testing a Digital Health Tool for INterseCtional Stigma Assessment and Reduction at Multiple Levels and mUltiple DimEnsions (INCLUDE) to Improve HIV Care in ART Centers in Nepal
People living with HIV (PLWH) have poor clinical outcomes when they are excluded from care due to intersectional stigma related to HIV, mental health (MH), and other dimensions.
- Conditions
- HIV Care Loss to Followup, HIV Antiretroviral Therapy (ART) Adherence, HIV Stigma, Mental Health Conditions
- Trial name
- INCLUDE (NCT07370298)
- Testing
- INCLUDE
- Where
- Nepal
- Volunteers
- 88 people
- Sponsor
- Possible
Hiv, HIV/AIDS
AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial
AllyQuest (AQ) is a theory-informed smart phone application that supports HIV medication adherence for young men who have sex with men and young transgender women who have sex with men (YMSM/YTW) via behavior change, social…
- Conditions
- Hiv, HIV/AIDS, Medication Adherence, Sexual Behavior
- Trial name
- AQ2 (NCT03916484)
- Testing
- AllyQuest HIV Medication Adherence app-delivered intervention, AllyQuest HIV Medication Adherence app-delivered intervention + NSC
- Where
- 6 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV/AIDS
Suubi4Her: Combination Intervention for Adolescent Girls Transitioning Into Adulthood in Uganda
This study examines the impact and cost associated with Suubi4Her, an innovative combination intervention that aims to prevent HIV risk behaviors among 15-17 year-old girls living in communities heavily affected by poverty and…
- Trial name
- NCT03307226
- Testing
- Youth Development Accounts (YDA), YDA + Multiple Family Groups (MFG)
- Where
- 2 sites in Uganda
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV, AIDS
Social Network Intervention to Engage Out-of-Care PLH Into Treatment
Formative Research Phase (Months 1-6) The investigators will undertake qualitative formative studies to: (1) identify barriers to highly active antiretroviral therapy (HAART) and strategies currently used to engage PLH in care…
- Trial name
- NCT01825018
- Testing
- Social Network Leader Endorsement, HIV Counseling
- Where
- Russia
- Volunteers
- 721 people
- Sponsor
- Medical College of Wisconsin
HIV
Managerial Database II
This study will collect information on health status and risk behaviors, as well as basic demographic and biomedical information for a group of HIV positive adolescents receiving care at the ATN sites.
- Trial name
- NCT01009827
- Testing
- Observation
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 1,712 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV
AIMS Study: Improving HIV Treatment Adherence
The objectives of the main study are to evaluate the effectiveness and the cost-effectiveness of a counseling intervention to support medication intake among patients treated for HIV.
- Trial name
- AIMS (NCT01429142)
- Testing
- Treatment as usual, AIMS intervention
- Where
- 7 sites in Netherlands
- Volunteers
- 226 people
- Sponsor
- Wageningen University
HIV/AIDS
An mHealth Intervention to Improve Outcomes for Women With HIV/AIDS
The purpose of this study is: 1. To develop a new mobile health (mHealth) system that will send text messages to remind both pregnant and non-pregnant women with HIV to adhere to their treatment plan (like keeping appointments…
- Trial name
- NCT03738410
- Testing
- Mobile Health Messaging application, Standard of Care Treatment
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
HIV Prevention, PrEP
Using Smart Phone Technology to Support PrEP Uptake and Adherence
This is a single arm pilot study of a new smartphone app to support adherence to PrEP medication for HIV prevention in public clinics in Virginia.
- Conditions
- HIV Prevention, PrEP, Adherence, Medication
- Trial name
- prep'd (NCT04868383)
- Testing
- Use of smart phone technology to support medication adherence and uptake
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Virginia
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT03652623
- Testing
- TDF/FTC
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
HIV Infections
Telephone Support to Improve Adherence to Anti-HIV Medications
This study tested a system of nursing telephone support to determine if it improves adherence to antiretroviral therapy (ART) in at-risk, treatment-experienced people.
- Trial name
- NCT00988442
- Testing
- Enhanced nursing telephone support, Standard care
- Where
- 16 sites in United States
- Volunteers
- 59 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Human Immunodeficiency Virus
Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs
The purpose of this study is to assess the tolerability, adherence and efficacy of single tablet dolutegravir/abacavir/lamivudine antiretroviral therapy in people living with HIV with a history of injection drug use (IDU)…
- Trial name
- TAISTR (NCT02659761)
- Testing
- dolutegravir/abacavir/lamivudine
- Where
- Ireland
- Volunteers
- 33 people
- Sponsor
- University College Dublin
HIV Infections
Effects of a Nurse-delivered Cognitive Behaviour Therapy on Adherence and Depressive Symptoms in HIV Infected Persons of South Korea
Cognitive behaviour therapy (CBT) has repeatedly been found to effectively treat depression in adult populations, and CBT for adherence and depression (CBT-AD) is an effective treatment for improving depressive symptoms and…
- Trial name
- NCT03823261
- Testing
- Cognitive Behavioral Therapy
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Yonsei University
Directly Observed Therapy, HIV Infections
Directly Observed Therapy in High Risk Populations in Newark, NJ
30 patients with poor antiretroviral therapy compliance will be identified from our pool of patients at Saint Michael's Medical Center and be given Directly observed therapy.
- Trial name
- NCT00285883
- Testing
- Invirase, Norvir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Saint Michael's Medical Center
Acceptability of Health Care, HIV Primary Infection
A Multicomponent Intervention to Address Gender-based Violence in HIV
This project seeks to adapt and pilot a trauma-informed combination intervention named 'Kickin' it with the Gurlz' that was designed with, for, and by transgender women of color to improve HIV prevention continuum outcomes.
- Trial name
- NCT04799197
- Testing
- Kicking it with the Gurlz
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley
HIV
An Educational and Supportive Counseling Program for Increasing Antiretroviral Use and Adherence in People With HIV
This study will develop and test the effectiveness of an educational and supportive counseling program called Preparing Patients to Start Antiretroviral Therapy in helping people with HIV make informed decisions about their…
- Trial name
- NCT00611429
- Testing
- Counseling sessions, Group workshop
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Medication Adherence, HIV/AIDS
A Mobile Gaming App to Improve Adherence to PrEP
In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi.
- Trial name
- NCT05762705
- Testing
- Multilevel Gaming Adherence Intervention, Treatment as Usual +
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Human Immunodeficiency Virus (HIV)
Assessment of Group Peer Support to Children With HIV in Vietnam
This project aims to assess the effect of group peer support to children with HIV in relation to adherence, virological treatment failure as well as physical development.
- Trial name
- NCT02035969
- Testing
- Enhanced Treatment Support (ETS)
- Where
- Vietnam
- Volunteers
- 520 people
- Sponsor
- Karolinska Institutet
Hepatitis C, Medication Adherence
Intensive Models of HCV Care for Injection Drug Users
Injection drug users (IDUs) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). HCV treatment leading to sustained viral response (SVR) is associated with increased survival.
- Trial name
- NCT01857245
- Testing
- Intensive Models (mDOT and CGT) of HCV Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Prisma Health-Upstate