Clinical trials: HIV Treatment Adherence
HIV
A Parenting and Self-Care Intervention for HIV Infected Mothers
The IMAGE intervention was developed to improve parenting and self-care skills in mothers infected with HIV. It is expected that an improvement in these areas will in turn improve the mother's physical and mental health as well…
- Trial name
- IMAGE (NCT01586988)
- Testing
- IMAGE Intervention
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of California, Los Angeles
Pre-Exposure Prophylaxis, Telemedicine
mHealth Facilitated Intervention to Improve HIV Pre-Exposure Prophylaxis Adherence
If taken every day, PrEP is an effective method for preventing HIV. However, many prescribed PrEP in the U.S. do not take it every day, as prescribed.
- Conditions
- Pre-Exposure Prophylaxis, Telemedicine, Medication Adherence
- Trial name
- SMART PrEP (NCT04990583)
- Testing
- Face-to-Face PrEP Adherence Intervention Based on LifeSteps, Adherence Coaching Facilitated by Carium Adherence App
- Where
- United States
- Sponsor
- Rhode Island Hospital
Human Immunodeficiency Virus
Optimizing Retention in Care and Adherence to Anti-retroviral Therapy Amongst Adolescents Living With HIV in Rwanda
HIV has now become the leading cause of death amongst adolescents in Africa with over 2.1 million adolescents (aged 10-19 years old) living with HIV today.
- Trial name
- NCT04531605
- Testing
- YBank program
- Volunteers
- 72 people
- Sponsor
- Youth Development Labs, Inc dba YLabs
Opioid-use Disorder, Adherence, Medication
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom.
- Conditions
- Opioid-use Disorder, Adherence, Medication, HIV Infections
- Trial name
- NCT04479475
- Testing
- Supportive care through community support persons
- Where
- Tanzania
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
AIDS, HIV Infections
Social-Psychological Intervention to Improve Adherence to HAART
All eligible patients will be invited to use electronic monitoring of medication (MEMS) during the next six months. After two months with MEMS the enrolled patients will be randomized to intervention group or to control group.
- Trial name
- SPIAH-Q (NCT00716040)
- Testing
- Social-psycho intervention to improve adherence to HAART, Usual care
- Where
- Brazil
- Volunteers
- 121 people
- Sponsor
- University of Sao Paulo
Human Immunodeficiency Virus, Alcohol-Related Disorders
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
The purpose of this study is to evaluate a stepped care behavioral intervention for HIV medication adherence and substance use ("Khanya") integrated into an HIV primary care setting in South Africa.
- Conditions
- Human Immunodeficiency Virus, Alcohol-Related Disorders, Drug Use, Substance Use
- Trial name
- NCT05933226
- Testing
- Khanya
- Where
- South Africa
- Volunteers
- 160 people
- Sponsor
- University of Maryland, College Park
HIV Prevention, HIV Risk
Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation
The goal of this study is to test if a Digital PrEP Toolkit helps cisgender women learn about and access PrEP in Alabama and Mississippi. PrEP is a medication that prevents HIV infection.
- Conditions
- HIV Prevention, HIV Risk, Sexual and Reproductive Health
- Trial name
- NCT07292584
- Testing
- Interactive Digital PrEP Toolkit
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome
HIV Medication Adherence in Underserved Populations
The purpose of this study is to determine whether cognitive rehabilitation or psychoeducation impacts medication adherence in HIV-1 seropositive individuals.
- Trial name
- NCT02392884
- Testing
- Cognitive Rehabilitation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
HIV, Acquired Immunodeficiency Syndrome
The Efficacy of the HIV/AIDS Symptom Management Manual
The goals of this research are: 1) To test the efficacy of a self-care symptom management manual by examining whether people who use the manual find it to be useful; 2) To examine symptom and demographic data related to self-care…
- Trial name
- NCT00241202
- Testing
- Symptom Management Manual
- Where
- 11 sites in United States, Kenya and 2 more
- Volunteers
- 775 people
- Sponsor
- University of California, San Francisco
HIV - Human Immunodeficiency Virus, HIV Antiretroviral Therapy (ART) Adherence
Improving the HIV Care Continuum With mHealth Technology
Youth living with HIV (YLHIV) face barriers to engagement and retention in HIV care, show poor medication adherence, and often fail to achieve and maintain viral suppression.
- Conditions
- HIV - Human Immunodeficiency Virus, HIV Antiretroviral Therapy (ART) Adherence, mHealth Application, mHealth Intervention
- Trial name
- NCT07631104
- Testing
- MindBodyU Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Carolina
HIV/AIDS, Medication Adherence
Centralized Off-Site Adherence Enhancement Program
Our proposal "Centralized Off-Site Adherence Enhancement Program" or "CARE" will develop and test an effective behavioral adherence intervention program for HIV patients with alcohol and/or substance abuse problems.
- Trial name
- CARE (NCT01409655)
- Testing
- cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, Los Angeles
Human Immunodeficiency Virus
Medication Adherence in Human Immunodeficiency Virus (HIV)
Although effective treatments are currently available to treat human immunodeficiency virus (HIV), the retrovirus leading to acquired immune deficiency syndrome (AIDS), strict adherence to the treatment regimen is required.
- Trial name
- NCT02119390
- Testing
- Staff-delivered intervention sessions, Demographic Questionnaire, Questionnaires
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- St. Jude Children's Research Hospital
HIV Infections, Pregnancy Related
mWACh-PrEP: A SMS-based Support Intervention to Enhance PrEP Adherence During Pregnancy and Breastfeeding
In high HIV prevalence regions, women are at high risk for HIV during pregnancy and breastfeeding. To protect women and reach elimination of mother-to-child HIV transmission, the World Health Organization recommends offering oral…
- Conditions
- HIV Infections, Pregnancy Related, Adherence, Medication
- Trial name
- NCT04472884
- Testing
- mWACh-PrEP, Standard of Care
- Where
- 4 sites in Kenya
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections, Acquired Immunodeficiency Syndrome
Effectiveness of Enhanced Counseling and Observed Therapy on Antiretroviral Adherence in People With HIV
This study will compare the effectiveness of enhanced counseling alone versus enhanced counseling combined with observed therapy at improving medication adherence in people with HIV.
- Trial name
- NCT00602758
- Testing
- Motivational interviewing with cognitive behavioral therapy, Modified directly observed therapy
- Where
- 4 sites in United States
- Volunteers
- 252 people
- Sponsor
- University of Missouri, Kansas City
HIV, AIDS
Cell Phone Intervention to Support Antiretroviral Therapy (ART) Adherence in Kenya
A clinical study to evaluate the use of cell phones to support drug adherence and follow-up of patients taking antiretroviral therapy (ART) for treatment of HIV.
- Conditions
- HIV, AIDS, HIV Infections
- Trial name
- NCT00830622
- Testing
- Cell Phone Intervention
- Where
- Kenya
- Volunteers
- 536 people
- Sponsor
- University of Manitoba
HIV Infections
Boosted Atazanavir and Truvada Given Once-Daily - BATON Study
To determine the safety and efficacy of a simple, once-daily antiretroviral (ARV) regimen consisting of a fixed-dose combination tablet containing Truvada combined with atazanavir boosted with ritonavir in treatment naive…
- Trial name
- NCT00224445
- Testing
- Truvada, Atazanavir, Ritonavir
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Gilead Sciences
AIDS, Antiretroviral Therapy
The Impact of Short Message Services (SMS) on ARV Adherence in Western Kenya
The purpose of proposed research is to implement a randomized study that will allow us to understand and address a number of key barriers to patient adherence as well as study the effects of better adherence on health and…
- Conditions
- AIDS, Antiretroviral Therapy, Medication Adherence, HIV Infections
- Trial name
- CAPS (NCT01058694)
- Testing
- Short Message Services to Support ARV therapy adherence
- Where
- Kenya
- Volunteers
- 720 people
- Sponsor
- Georgetown University
HIV
City-Wide Implementation and Evaluation of the B-OK Bottles for HIV Treatment Adherence Support in the Philadelphia Ryan White Medical Case Management Network
The researchers will conduct a hybrid implementation-effectiveness study of a city-wide B-OK rollout led by PDPH with research and evaluation support from the University of Pennsylvania.
- Trial name
- B-OK PDPH (NCT07807137)
- Testing
- B-OK Bead Bottles
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Disorders, HIV Infections
Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- Switch-ER (NCT00944957)
- Testing
- Raltegravir for the first 2 weeks, Efavirenz for the last 2 weeks, Efavirenz for the first 2 weeks
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
HIV, AIDS
Increasing Social Support to Improve HIV Care Engagement and Adherence in St. Petersburg, Russia
Prior research has documented serious health, mental health, and social-behavioral issues among people living with HIV (PLH) in St. Petersburg.
- Trial name
- NCT02167828
- Testing
- Social Support
- Where
- 2 sites in United States, Russia
- Volunteers
- 174 people
- Sponsor
- Medical College of Wisconsin