Clinical trials: HIV Treatment Adherence
Acute HIV Infection, Acquired Immunodeficiency Syndrome
HAART Adherence Among HIV-infected Persons and the Factors Affecting Treatment Adherence
The general objective of this study is to evaluate HAART adherence in Estonia and the factors affecting adherence; and the impact of an individual adherence enhancement counselling and treatment monitoring model (Advanced…
- Conditions
- Acute HIV Infection, Acquired Immunodeficiency Syndrome, Medication Adherence
- Trial name
- NCT01369056
- Testing
- Advanced Adherence Counseling (AdvAdh)
- Where
- Estonia
- Volunteers
- 150 people
- Sponsor
- University of Tartu
Medication Adherence, HIV/AIDS
A Mobile Gaming App to Improve ART Adherence for Youth
Despite the need for consistent adherence to medical care, youth living with HIV have low rates of adherence to medications and treatment.
- Trial name
- NCT03760211
- Testing
- Multilevel Gaming Adherence Intervention, Treatment as Usual +
- Where
- 4 sites in United States
- Volunteers
- 107 people
- Sponsor
- Rhode Island Hospital
HIV Infections, HIV Seronegativity
HIV Incidence and Participation Retention in Pune, India
The purpose of this study is to ensure that the HIV Prevention Trials Unit (HPTU) in Pune will be able to enroll and retain participants for 2 upcoming HPTN clinical trials.
- Trial name
- NCT00028119
- Where
- India
- Volunteers
- 1,070 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Human Immunodeficiency Virus (HIV) Infection
Interventions to Improve HIV Antiretroviral Therapy Adherence
This study will explore whether financial incentives, reminders, information about HIV/AIDS and its treatment and anti-stigma counseling help improve anti-retroviral therapy (ART) adherence among HIV infected individuals in a…
- Trial name
- NCT03618511
- Testing
- Financial Incentive, Reminders, Financial Incentive and Reminders
- Where
- Mozambique
- Volunteers
- 914 people
- Sponsor
- University of Michigan
Human Immunodeficiency Virus
Mother and Infant Visit Adherence and Treatment Engagement Study
This is a 2x2 factorial cluster randomized trial of two interventions to improve retention and adherence for women and infants on Option B+.
- Trial name
- MOTIVATE! (NCT02491177)
- Testing
- cMM, Text Messaging
- Where
- Kenya
- Volunteers
- 1,338 people
- Sponsor
- University of Colorado, Denver
Body Image Disturbance, Medication Adherence
Body Image and Self-Care in HIV-Infected MSM
The purpose of this study is to develop and test counseling strategies for men who have sex with men (MSM) who are living with HIV and are experiencing body dissatisfaction.
- Trial name
- BUILD (NCT01817621)
- Testing
- Experimental Intervention, TAU
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
HIV/AIDS
Behavioral Economics Incentives to Support HIV Treatment Adherence in Sub-Saharan Africa
This study will implement an intervention in a two-year randomized controlled trial (RCT) to establish efficacy on viral suppression as a biological endpoint, compare the effectiveness of two different modes of implementation…
- Trial name
- NCT03494777
- Testing
- Incentivization based on high adherence, Incentivization based on timely clinic visit, Annual adherence prize drawing
- Where
- Uganda
- Volunteers
- 331 people
- Sponsor
- RAND
HIV/AIDS
Contribution of "Praise Messages" to HIV Treatment Retention and Adherence Among Female Sex Workers in Ethiopia
This study evaluates the effects of praise message phone calls on antiretroviral therapy (ART) initiation, adherence, and prescription refills.
- Trial name
- NCT03127397
- Testing
- Praise message phone call
- Where
- Ethiopia
- Volunteers
- 810 people
- Sponsor
- Reed College
HIV Infections, Tuberculosis
Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings
Tuberculosis (TB), a bacterial infection common in HIV infected people, is a major problem in developing countries. The purpose of this study is to test the effectiveness of a combined treatment strategy using directly observed…
- Trial name
- NCT00091936
- Testing
- Didanosine, Efavirenz, Lamivudine
- Where
- 2 sites in South Africa
- Volunteers
- 592 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Pregnancy
Cash Transfers to Pregnant Women With HIV
The goal of this study is to evaluate the effectiveness and implementation of an unconditional cash transfer intervention to improve mental bandwidth, ART adherence, and postpartum retention among pregnant women with HIV in…
- Conditions
- HIV, Pregnancy, HIV Antiretroviral Therapy (ART) Adherence, Post-partum
- Trial name
- NCT07226492
- Testing
- Unconditional Cash Transfer (UCT)
- Where
- 8 sites in Botswana
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
HIV
Substance Use Disorders in HIV People of Cameroon
Background: Data are scarce concerning injecting drug use (IDU) and alcohol consumption among HIV-infected people on highly active antiretroviral treatment (HAART) in Cameroon.
- Trial name
- NCT02356185
- Volunteers
- 1,000 people
- Sponsor
- Goulfey Health District Unit
Hiv, Mental Health Issue
Striving Towards EmPowerment and Medication Adherence R01
This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and…
- Trial name
- NCT06463886
- Testing
- STEP-AD, Enhanced treatment as usual (E-TAU)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Miami
HIV Infections
Seek, Test, Treat, Retain: An Integrated Jail-Prison-Community Model for Illinois
Aim-1: Evaluate opt-out versus opt-in testing for the human immunodeficiency virus (HIV) at the Cook County jail and the Illinois Department of Corrections Northern Intake facilities.
- Trial name
- NCT01852877
- Testing
- Corrections case management
- Where
- 3 sites in United States
- Volunteers
- 784 people
- Sponsor
- University of Illinois Chicago
HIV, Adherence
mHealth Intervention Supporting HIV Treatment Adherence and Retention
Despite advances in antiretroviral treatment (ART) over the past 10 years, the incidence of HIV in the United States remains stagnant with over 50,000 new cases annually.
- Conditions
- HIV, Adherence, Retention
- Trial name
- NCT01951092
- Testing
- Text messaging
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The Miriam Hospital
Substance-Related Disorders, Substance Use
Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care
Alcohol and other drug use is common among people living with HIV in South Africa and is associated with worse engagement in HIV care.
- Conditions
- Substance-Related Disorders, Substance Use, Substance Use Disorders, Stigma, Social
- Trial name
- NCT05907174
- Testing
- Siyakhana - P
- Where
- South Africa
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Stimulant Use Disorder, People Living With HIV
reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)
The purpose of this study is to find out if reSET, an FDA authorized mobile therapeutic, is effective in treating stimulant use disorder and helping keep HIV viral load suppression stable among men who have sex with men who are…
- Trial name
- COSTA (NCT05958017)
- Testing
- reSET, Standard of care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Miami
HIV Infections
A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation
Anti-HIV drug therapy works best when the drugs are taken exactly as prescribed by a doctor. Because anti-HIV therapy often involves multiple drugs, some people have difficulty taking them all correctly.
- Trial name
- NCT00036452
- Testing
- lopinavir/ritonavir, emtricitabine, stavudine
- Where
- 29 sites in United States, Puerto Rico and 1 more
- Volunteers
- 402 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sleep Disorders
Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- SWITCH-EE (NCT00792584)
- Testing
- etravirine, efavirenz
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Treatment Adherence and Compliance
PrEP iT! Mobile App Intervention
The long-term goal of this research is to create an effective and sustainable program to support retention in PrEP care and PrEP adherence among 18-29 year old men who have sex with men (MSM).
- Trial name
- PrEP iT! (NCT04509076)
- Testing
- PrEP iT! (plus usual PrEP care), Usual PrEP care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- San Diego State University
HIV, Medication Adherence
Mobile Health Application to Improve HIV Medication Adherence
Inadequate adherence to antiretroviral therapy (ART) can impede successful viral suppression and consequently lead to negative health consequences.
- Conditions
- HIV, Medication Adherence, Mobile Health
- Trial name
- NCT02676128
- Testing
- Twine Collaborative Care Application, Information-Motivation-Behavioral Skills Model of ART Adherence
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rhode Island Hospital