Clinical trials: HIV Treatment Adherence
Human Immunodeficiency Virus
The SUSTAIN 2 Study - SUStained HIV Treatment for Adherence After Interruption in Care
The goal of this clinical trial is to learn if the DSD model (SUSTAIN-DSD) is effective in improving participants HIV treatment adherence.
- Trial name
- NCT06554223
- Testing
- SUSTAIN-DSD, Enhanced (guideline-driven) Standard of Care (E-SoC)
- Where
- South Africa
- Volunteers
- 310 people
- Sponsor
- Brigham and Women's Hospital
Human Immunodeficiency Virus (HIV) Infection, HIV Prevention
Empowering Knowledge, Self-Testing & Resilience Through Innovative Methods for HIV
The goal of this study is to learn whether a digital tool can help improve HIV knowledge, self-awareness, and testing among adolescents in Yogyakarta, Indonesia.
- Conditions
- Human Immunodeficiency Virus (HIV) Infection, HIV Prevention, Adolescent Health, Digital Education Interventions
- Trial name
- EKSTRIM (NCT07039682)
- Testing
- Digital HIV Education and Self-Screening (EKSTRIM Model)
- Where
- Indonesia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
HIV-related Stigma, Patient Satisfaction
POL and Access Intervention to Reduce HIV Stigma Among Service Providers in China
In this project, UCLA's Center for Community Health (CCH) will develop an efficacious intervention trial integrating both individual and structural components to reduce HIV- related stigma among service providers in China and…
- Conditions
- HIV-related Stigma, Patient Satisfaction, Provider-patient Interaction
- Trial name
- NCT01052415
- Testing
- Cognitive behavioral sessions
- Where
- United States
- Volunteers
- 5,400 people
- Sponsor
- University of California, Los Angeles
HIV, Alcoholism
Will Having Alcohol Treatment Improve Functioning?
The purpose of the study is to find out if a medication,naltrexone is helpful for HIV-infected women who sometimes drink too much.
- Trial name
- WHAT-IF (NCT01245647)
- Testing
- Naltrexone, 50mg, once per day for 4 months, Sugar pill, 50mg, once per day for 4 months
- Where
- 3 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Florida
ART Adherence
Efficacy of mHealth + e-Navigator Stepped Care Intervention for ART Adherence Among Latino Men With HIV
The goal of this study is to evaluate the efficacy of stepped care strategies to improve ART adherence among adult Latino men with HIV using a sequential, multiple assignment, randomized trial (SMART).
- Trial name
- Project STEP (NCT06375135)
- Testing
- TXTXT, e-Navigation, Ecological Momentary Assessment (EMA) supported e-Navigation.
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Florida International University
HIV
WhatsApp Intervention to Assess the Effect of Messages in Adherence to Antiretrovirals in Young People With HIV in Peru
The goal of this clinical trial is to learn which type of messages is more efficacious to improve adherence to medication in young people living with HIV.
- Trial name
- NCT06500013
- Testing
- Self-designed messages, Standardized messages
- Where
- Peru
- Volunteers
- 131 people
- Sponsor
- Universidad Peruana Cayetano Heredia
HIV
Antiretroviral Therapy Adherence and Secondary Prevention of Human Immunodeficiency Virus
In this study, investigators propose to randomize 165 human immunodeficiency virus positive patients to one of three 16-week treatment conditions: (1) standard care; (2) standard care + cell phone-based adherence reminders; or…
- Trial name
- NCT01760759
- Testing
- cell phone reminders, contingency management for adherence
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- UConn Health
Medication Adherence, HIV
Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs
This is a single-center, open label study to identify adherence levels of commonly prescribed FDA-approved antiretroviral agents by tracking the decline of drug concentrations in plasma, urine and saliva following abrupt drug…
- Trial name
- APTAMER (NCT04302896)
- Testing
- dolutegravir oral tablet 50mg, emtricitabine/tenofovir alafenamide oral tablet 200mg/25mg, tenofovir disoproxil fumarate oral tablet 300mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rhonda Brand
HIV Infections, Acquired Immunodeficiency Syndrome
Text Messaging to Improve Adherence to Clinic Visits and Reduce Early Resumption of Sexual Intercourse After Male Circumcision
Male circumcision (MC) reduces, by more than half, the risk of HIV-1 acquisition. WHO and UNAIDS recommend that "male circumcision should be recognized as an efficacious intervention for HIV prevention especially in countries and…
- Conditions
- HIV Infections, Acquired Immunodeficiency Syndrome, Circumcision, Male, Patient Compliance
- Trial name
- NCT01186575
- Testing
- Text Message
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV
Same-Day HIV Testing and Treatment Initiation to Improve Retention in Care
The purpose of this study is to determine if same-day HIV testing and antiretroviral therapy (ART) initiation improves retention in care (as measured by the proportion of participants who are alive and in-care with an…
- Trial name
- NCT01900080
- Testing
- Same-Day HIV testing and ART initiation, Standard ART Initiation, Sub-Study: Same-Day ART, CD4 Count >500
- Where
- Haiti
- Volunteers
- 814 people
- Sponsor
- Brigham and Women's Hospital
Risk Behavior, HIV/AIDS
Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs
This study will evaluate the efficacy and cost-effectiveness of CHRP-BB - an integrated bio-behavioral approach that incorporates the use of PrEP - with an evidence-based behavioral approach aimed at enhancing PrEP adherence and…
- Conditions
- Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
- Trial name
- CHRP-BB (NCT03282890)
- Testing
- CHRP-BB
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Connecticut
HIV/AIDS
DHFS for Medication Adherence Support During Hospital Admissions for Person Living With HIV
This study is a prospective single arm open label intervention study over 16 weeks using the DHFS and a telemedicine platform with persons living with HIV who are not virologically suppressed, admitted to UCSD Hillcrest Medical…
- Trial name
- NCT04418037
- Testing
- Digital Health Feedback System(DHFS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Diego
Human Immunodeficiency Virus I Infection
An Automated, Tailored Information Application for Medication Health Literacy
The purpose of this study is to evaluate the acceptability and efficacy of a computer-based tailored information application designed to promote health literacy in persons treated for HIV infection.
- Trial name
- NCT01304186
- Testing
- Tailored Information
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Nova Southeastern University
HIV Infection
Characterization of the Adherence Threshold for HIV Suppression of a Kaletra-based Regimen
The hypothesis of this study is that the level of adherence necessary to achieve HIV virologic suppression with a ritonavir boosted protease inhibitor regimen (i.e.
- Trial name
- NCT00200369
- Testing
- MEMS cap
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Montefiore Medical Center
HIV/AIDS, Adherence, Medication
Improving Engagement in HIV Care for High-risk Women
Transgender women (assigned 'male' at birth but who do not identify as male) are disproportionately impacted by HIV and have culturally unique barriers and facilitators to engagement in HIV care.
- Trial name
- NCT03081559
- Testing
- Healthy Divas
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus Infection
Treatment Perception of QD (Once a Day) Dosed Kaletra (Tablets)
Both twice-a-day (BID) and once-a-day (QD) dosing are approved in Europe for the protease inhibitor lopinavir/ritonavir (LPV/r; Kaletra®).
- Trial name
- QD-Kapital (NCT01383005)
- Where
- 20 sites in Spain
- Volunteers
- 97 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
HIV, Medication Adherence
Intervention Targeting Substance Using Older Adults With HIV
The proposed study uses a randomized controlled experimental design to evaluate the efficacy of a brief intervention using spiritual self schema (3S+) counseling to simultaneously target HIV health outcomes, and substance use…
- Conditions
- HIV, Medication Adherence, Substance Dependence
- Trial name
- NCT01305629
- Testing
- Spiritual Self-Schema Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Hunter College of City University of New York
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse
Reducing Hazardous Alcohol Use and Optimizing Treatment as Prevention Among Men Living With HIV in Risk Environments
The investigators developed the Kisoboka ("It is possible") Intervention to address limitations of existing evidence-based interventions to optimize treatment as prevention among men living with HIV who drink alcohol at hazardous…
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse, HIV Infection, Alcohol Use Disorder
- Trial name
- Kisoboka (NCT06771843)
- Testing
- Kisoboka, Behavioral Economics, Motivational Interviewing
- Where
- Uganda
- Volunteers
- 716 people
- Sponsor
- San Diego State University
Risk Behavior, Medication Adherence
Secondary HIV Prevention and Adherence Among HIV-infected Drug Users
This study will test whether 3H+ (Holistic Health for HIV) is comparable to the original HHRP+ (Holistic Health Recovery Program) in reducing HIV risk behaviors and improving ART (Antiretroviral Therapy) adherence in a randomized…
- Conditions
- Risk Behavior, Medication Adherence, HIV
- Trial name
- NCT01741311
- Testing
- 3H+ (Holistic Health for HIV), HHRP+ (Holistic Health Recovery Program)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Connecticut
Depression, Posttraumatic Stress Disorder
Randomized Controlled Trial of Interpersonal Psychotherapy for Depression and PTSD Among HIV+ Women in Kenya
The aim of this study is to conduct a 12-week IPT+TAU versus wait list TAU in a cohort of HIV+GBV+ women in Nyanza Province to relieve depression and PTSD and improve ARV adherence.
- Conditions
- Depression, Posttraumatic Stress Disorder, HIV
- Trial name
- NCT02320799
- Testing
- interpersonal psychotherapy, treatment as usual
- Where
- Kenya
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco