Clinical trials: HIV Treatment Adherence
HIV Infection, HIV Infections
QoL and Adherence to One-pill Once-a-day HAART
Primary objective of the study is: To verify if simplification of the antiretroviral regimen, measured as the reduction of pill burden alone, may affect adherence rate of patients.
- Trial name
- ADONE (NCT00990600)
- Testing
- reduced number of pills
- Volunteers
- 212 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
HIV Infections
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial
YouTHrive (YT) is a two-arm randomized control trial (RCT) to test the efficacy of an adapted version of the Thrive With Me (TWM) intervention for youth living with HIV (YLWH).
- Trial name
- NCT03149757
- Testing
- YouTHrive, Information-only Control
- Where
- 7 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
HIV Infections, Sexually Transmitted Diseases
Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
The purpose of this study is to compare the effectiveness of two mobile health technologies (text messaging or a mobile app) designed to help people take HIV pre-exposure prophylaxis (PrEP) as directed by the clinic.
- Trial name
- PCORI PrEP (NCT04855773)
- Testing
- PrEPmate, Dot Diary
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
HIV Infections, Mental Health
BEYOND Study: Improving HIV Treatment and Well-Being Among Young MSM in Vietnam
The BEYOND Study aims to evaluate HIV treatment outcomes and well-being among young men who have sex with men (YMSM) living with HIV in Ho Chi Minh City, Vietnam.
- Conditions
- HIV Infections, Mental Health, Medication Adherence
- Trial name
- BEYOND (NCT07559266)
- Testing
- NO interventions listed
- Where
- Vietnam
- Volunteers
- 300 people
- Sponsor
- Center for Applied Research on Men and Community Health, Vietnam
HIV
Etiology of Treatment Failure in HIV Positive Children and Adolescents on Boosted Protease Inhibitor-based Regimens
Highly active antiretroviral therapy (HAART) transformed a once fatal condition into a chronic, manageable condition. However, it is estimated that 20-40% of patients on 2nd line treatment (2 nucleotide reverse transcriptase…
- Trial name
- ATF (NCT02689895)
- Testing
- modified directly administered anti-retroviral therapy (mDAART)
- Where
- 2 sites in Zimbabwe
- Volunteers
- 50 people
- Sponsor
- University of Zimbabwe
Hepatitis C, Chronic, HIV Infection
ADHEPTA Study: Adherence Questionnaire in Hepatitis C
Main objective: To study and validate a questionnaire measuring treatment adherence in patients with Hepatitis C virus (HCV) infection.
- Trial name
- ADHEPTA (NCT00998621)
- Testing
- Adherence questionnaire
- Where
- Spain
- Volunteers
- 1,120 people
- Sponsor
- Fundacion IMIM
HIV-1
PI or NNRTI as First-line Treatment of HIV in West Africa - the PIONA Trial
BACKGROUND: Since 1996 the combination of three or more drugs has been the mainstay of human immunodeficiency virus (HIV) treatment.
- Trial name
- PIONA (NCT01192035)
- Testing
- Efavirenz or Nevirapine, Ritonavir-boosted lopinavir
- Where
- Guinea-Bissau
- Volunteers
- 400 people
- Sponsor
- University of Aarhus
HIV Infections
A Spanish-Language Intervention to Enhance Routine HIV Patient Care Delivery [CARE+ Spanish]
The purpose of this study is to see if a computer counseling tool helps Spanish-speaking people living with HIV to have safer sex and to do well on their HIV medicines.
- Trial name
- CARE+ Spanish (NCT01013935)
- Testing
- CARE+ Spanish computer counseling session, CARE+ Spanish brief computer risk assessment session
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- New York University
HIV, Tuberculosis
Evaluation of South Africa's National Adherence Strategy
NOTE THAT THE STUDY IS LED BY SOUTH AFRICA NATIONAL DEPARTMENT OF HEALTH AND WORLD BANK WITH SUPPORT FROM BOSTON UNIVERSITY. The South Africa National Department of Health (NDOH) intends to launch its newly developed National…
- Conditions
- HIV, Tuberculosis, Diabetes, Hypertension
- Trial name
- ENHANCE (NCT02536768)
- Testing
- Minimum package of interventions to improve ART adherence
- Where
- South Africa
- Volunteers
- 8,020 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV
Improving Memory Performance by Applying Cognitive Training
The proposed study will test the efficacy of a cognitive training program to improve working memory in a sample of HIV-infected persons.
- Trial name
- IMPACT (NCT02216591)
- Testing
- Active Cognitive Training (ACT), Control (CON)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Duke University
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
HIV, Adolescent Development
Health Improvement for Baltimore Youth
Preliminary data from the investigators' National Center for Complementary and Alternative Medicine (NCCAM)-funded R21 on mindfulness-based stress reduction (MBSR) in HIV-infected youth suggest an association between mindfulness…
- Conditions
- HIV, Adolescent Development, Adolescent Behavior, Medication Adherence
- Trial name
- NCT02624193
- Testing
- MBSR Program, HT Program
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Johns Hopkins University
Smoking, Smoking Cessation
Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients
The purpose of this study is to learn if a mindfulness-based smoking cessation smartphone app can help people quit smoking and stay on antiretroviral therapies.
- Conditions
- Smoking, Smoking Cessation, HIV
- Trial name
- NCT03999411
- Testing
- Nicoderm C-Q Transdermal Product, Adherence to Antiretroviral Therapy Counseling, Behavioral Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Miami
Chlamydia Infections, Gonorrhea
Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections
Project FEDE-ITS will improve the STI knowledge and its treatment, of adolescents in the 1st and 2nd year of compulsory secondary education in the intervention group compared to compared to the control group, and will modify the…
- Conditions
- Chlamydia Infections, Gonorrhea, Syphilis Infection, Human Immunodeficiency Virus (HIV)
- Trial name
- FEDE-ITS (NCT05727033)
- Testing
- Participatory teaching group
- Where
- 4 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
HIV-infection/Aids
Novel Measures and Theory of Pediatric Antiretroviral Therapy Adherence in Uganda
Current measures of adherence detect problems weeks to months after they occur. Because the HIV virus rapidly begins replicating and mutating in the absence of effective antiretroviral therapy, treatment failure may develop…
- Trial name
- NCT01140633
- Where
- Uganda
- Volunteers
- 46 people
- Sponsor
- Massachusetts General Hospital
HIV Infections
Adherence Intervention for People With Low-literacy
Consistent adherence to antiretroviral therapy is necessary for treatment success. People with poor health literacy skills experience considerable difficulty adhering to their medications.
- Trial name
- NCT01061762
- Testing
- Stick To It, Standard medication adherence counseling, Health Counseling
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Connecticut
HIV/AIDS
M-Suubi: A Multi-Level Integrated Intervention to Reduce the Impact of HIV Stigma
M-Suubi, a three arm cluster randomized study will examine the effects and cost-effectiveness of a multi-level intervention on HIV viral suppression among 840 adolescents living with HIV (ALHIV) enrolled in 42 secondary schools…
- Trial name
- NCT05307250
- Testing
- Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE, Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE plus Group-based stigma reduction for educators (GED-HIVSR)., Bolstered Standard of Care (BSOC)
- Where
- Uganda
- Volunteers
- 1,851 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV Infections
Measure of Pharmacokinetic Parameters and Adherence With MEMS in Naive HIV Infected Patients Treated With Reyataz Once Daily Combined With Norvir and Truvada
the trial assessed the pharmacokinetics and long term plasma exposure of the following antiretrovirals: atazanavir when combined to ritonavir and the tenofovir/emtricitabine fixed-dose combination.
- Trial name
- ANRS134COPHAR3 (NCT00528060)
- Testing
- Atazanavir, Ritonavir, Tenofovir/emtricitabine
- Where
- 2 sites in France
- Volunteers
- 35 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
HIV/AIDS, Adherence, Medication
Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users
Despite increasing knowledge about and use of PrEP nationally, HIV continues to have disproportionate impact among cisgender men and transgender persons who have sex with men and transgender persons (MSM/TG), with methamphetamine…
- Conditions
- HIV/AIDS, Adherence, Medication, Drug Use
- Trial name
- NCT03584282
- Testing
- Text Messaging, Peer Navigation
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections, Men
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two…
- Conditions
- HIV Infections, Men, Treatment Adherence
- Trial name
- NCT05602376
- Testing
- U=U testing messaging scripts, U=U adherence messaging scripts
- Where
- 2 sites in South Africa
- Volunteers
- 3,642 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation