Clinical trials: HLA B27
Uveitis, Iritis
Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications
Retinal optical coherence tomography (OCT) is an established technology which enables a detailed cross-sectional visualization of the retinal micro-anatomy, and an objective measurement of its thickness in-vivo.
- Conditions
- Uveitis, Iritis, Iridocyclitis, Anterior Uveitis
- Trial name
- NCT00476593
- Testing
- Diclofenac, Dexamethasone
- Where
- 2 sites in Norway
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Ankylosing Spondylitis
Genetic Susceptibility to Ankylosing Spondylitis (AS) by Functional Genomics Approach
The main objective is to identify in the candidate regions of differentially expressed genes by comparing the transcriptome of dendritic cells derived from circulating monocytes between cases and controls.
- Trial name
- GENOSPA (NCT02525042)
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-infectious Uveitis
Safety and Efficacy of AIN457 in Noninfectious Uveitis
This study was performed to evaluate the efficacy and safety of AIN457 for patients with active uveitis that requires systemic immunosuppression.
- Trial name
- NCT00685399
- Testing
- AIN457, AIN 457
- Where
- 23 sites in United States, Germany
- Volunteers
- 76 people
- Sponsor
- Novartis Pharmaceuticals
Ankylosing Spondylitis
Ankylosing Spondylitis
The goal of this observational study is to measure the serum level of cytokines IL-17, IL-38,IL-41, and gene expression of HLA-B27 gene in ankylosing spondylitis patients and healthy control group.
- Trial name
- Interleukins (NCT07396194)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sohag University
Uveitis
Assessment of the Anti-inflammatory Effects of Norflo Oro in Acute Relapses of HLA-B27 Associated Autoimmune Uveitis
The purpose of this study is to explore the efficacy of Norflo Oro in the treatment of relapsing autoimmune uveitis (RAU), measured as a long term reduction of the frequency and the severity of relapses, in patients with HLA-B27…
- Trial name
- NCT03584724
- Testing
- Norflo Oro
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Eye Pharma
Arthritis, Spondylitis, Ankylosing
Natural History and Development of Spondyloarthritis
Background: Spondyloarthritis (SpA) is a group of bone and joint disorders that may cause back and joint pain and stiffness. In some cases, SpA can lead to abnormal bone growth affecting the joints and spine.
- Trial name
- NCT01422694
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Axial Spondyloarthritis
Microbiome and Axial Spondyloarthritis
The purpose of this interventional study is to identify the root cause(s) of AxSpA (Axial Spondyloarthritis) relapses, which are likely due to the combination of nutrition, gut microbiome activities, leaky gut, and human genes…
- Trial name
- NCT04713995
- Testing
- Dietary recommendations
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Viome
Spondylarthritis, Uveitis, Anterior
Observational Prospective Turkish Inception Cohort of Uveitis and Spondyloarthritis
Spondyloarthritis (SpA) encompasses a group of inflammatory rheumatic diseases characterized by axial and/or peripheral arthritis, along with extra-articular manifestations such as enthesitis, dactylitis, uveitis, and skin…
- Trial name
- OPTICUS (NCT06720376)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Psoriatic Arthritis, HLA b Leader
HLA B Leader in Patients With Psoriatic Arthritis
Psoriatic arthritis (PsA), a chronic immune-mediated heterogeneous inflammatory disease characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis and dactylitis), usually occurs in patients with psoriasis.
- Conditions
- Psoriatic Arthritis, HLA b Leader, HLA B27
- Trial name
- HLABLRP (NCT07718815)
- Testing
- blood test
- Where
- France
- Volunteers
- 658 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens