Clinical trials: HSP70
Peripheral Arterial Disease
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk
Introduction: Atherosclerotic Peripheral Arterial Disease (PAD) is the leading cause of mortality in the western world. To maintain homeostasis of the vessel wall, vascular cells produce a high level of heat shock proteins (HSP)…
- Trial name
- HSP70 (NCT04743128)
- Testing
- Exercise
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
Hepatocellular Carcinoma
Relationship Between Polymorphism of Heat Shock Protein 70 Gene and Hepatocellular Carcinoma
Polymorphisms of HSP70 and tumor necrosis factor-alpha promoter in patients with hepatocellular carcinoma, chronic liver disease and healthy controls will be measured by PCR-RFLP or direct sequencing.
- Trial name
- HSP70 (NCT00769535)
- Testing
- Polymorphisms of HSP70 and TNF promoter
- Where
- 2 sites in Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
HIV Infections
Reactogenicity and Immunogenicity of Cervico-vaginal CN54gp140-hsp70 Conjugate Vaccine
A vaccine to prevent infection with the Human Immunodeficiency Virus (HIV) is urgently needed. Worldwide, most HIV infections occur through sex between a man and woman.
- Trial name
- TL01 (NCT01285141)
- Testing
- CN54gp140 glycoprotein-hsp70 conjugate vaccine
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
HPV 16 Infection, HPV-Related Carcinoma
Clinical Trial Assessing the Safety and Immunologic Correlates of Heterologous Prime-Boost With pNGVL4a-Sig/E7(Detox)/HSP70 and TA-HPV in Healthy Donors Followed by Peripheral Blood Collection
This healthy related donor clinical trial is linked to a recipient clinical trial protocol for therapeutic purposes. In this healthy donor protocol, haploidentical relatives of a patient with recurrent or metastatic human…
- Conditions
- HPV 16 Infection, HPV-Related Carcinoma, Recurrence, Metastatic Cancer
- Trial name
- J21112LINKED (NCT06508138)
- Testing
- pNGVL4a-Sig/E7(detox)/HSP70 plasmid DNA; TA-HPV vaccinia virus
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sepsis, Systemic Inflammation
The Effect of Glutamine on Systemic Inflammation During Human Experimental Endotoxemia
Glutamine levels decrease during severe sepsis; this may be associated with increased mortality. The investigators tested the effects of glutamine supplementation on systemic inflammation in a human sepsis model.
- Trial name
- NCT00780520
- Testing
- alanine-glutamine infusion
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet