Clinical trials: Haemodialysis Complication
Renal Insufficiency, Chronic
Effect of Hemodialysis on Upper Airways Collapsibility in Patients With Chronic Kidney Disease
Introduction: Currently, chronic kidney disease (CKD) is one of the most serious public health problems, becoming a global epidemic.
- Trial name
- NCT02390193
- Testing
- Hemodialysis
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centro Universitário de Anapolis
Chronic Kidney Diseases, Hemodialysis Complication
Exposure Of Bisphenol Analogues In Chronic Kidney Disease and Dialysis Patients
In this retrospective study, the serum levels of Bisphenol A (BPA) and three BPA analogs, namely, bisphenol B (BPB), bisphenol S (BPS), and bisphenol F (BPF), in patients with CKD, patients on dialysis therapy and healthy control…
- Trial name
- NCT04100421
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Dialysis; Complications, Bleeding
The Safety of Nafamostat Mesylate for Patients With High Risk Bleeding Undergoing Hemodialysis: A Pilot Study
Comparison nafamostat and low molecular weight heparin among dialysis patients
- Trial name
- Nafamostat (NCT05874674)
- Testing
- Nafamostat Mesylate
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wonju Severance Christian Hospital
Chronic Kidney Diseases, Chronic Kidney Disease 5D
The Discrepancy in Radiologists' Practice of Intravenous Contrast Imaging Studies Among Chronic Kidney Disease Patients
There is a discrepancy between protocols used for intravenous imaging for chronic kidney disease including hemodialysis patients among different hospitals and even, among radiologists same selves.
- Trial name
- NCT05729126
- Testing
- Questionnare
- Where
- Egypt
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Benha University
Dialysis Related Complication
Lower Dialysate Temperature and Post-Dialysis Fatigue
The standard dialysate temperature is usually set at 36.5°C in hemodialysis applications. Since this temperature is close to the patient's body temperature, it is ideal for preventing the patient from experiencing hypothermia…
- Trial name
- NCT07071376
- Testing
- cold dialysis
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Baskent University
Renal Impairment
A Study to Investigate the Effect of Renal Function and Hemodialysis on the Pharmacokinetics (PK) of RO7079901
This is a multi-center, non-randomized, open-label, two-part study to investigate the effect of renal function and hemodialysis on PK of RO7079901.
- Trial name
- NCT02975388
- Testing
- RO7079901
- Where
- 5 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy
Effect of Renal Impairment on the Pharmacokinetics, and Safety of Megestrol Acetate Concentrated Suspension
To determine the pharmacokinetics and safety of megestrol acetate after a single oral 300 mg dose of megestrol acetate concentrated suspension in healthy subjects, and subjects with varying degrees of renal impairment
- Trial name
- NCT00637403
- Testing
- Megestrol acetate concentrated suspension 125 mg/mL
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
End Stage Kidney Disease
The Effect of Intradialytic Exercise on the Functional Capacity of Hemodialysis Patients
The purpose of this study is to explore the impact of an intradialytic exercise program on functional capacity, aerobic capacity, strength, quality of life, depression, hospitalizations and intradialytic episodes of hypotension.
- Trial name
- NCT01877863
- Testing
- exercise
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis
Hypoxemia in Maintenance Hemodialysis Patients
Previous research has shown that many patients with kidney failure undergoing chronic hemodialysis (HD) have a very low venous oxygen concentration, which may further decrease during dialysis treatments.
- Conditions
- Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis, Kidney Failure, Chronic
- Trial name
- NCT03045796
- Testing
- Oxygen Saturation measured by WristOx
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Renal Insufficiency, Kidney Diseases
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis
This is a multi-center, open-label, parallel-group study to evaluate oral doses of INCB054707 in participants with varying levels of renal function or impairment.
- Trial name
- NCT05624723
- Testing
- INCB054707
- Where
- 2 sites in United States, Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Hemodialysis Complication
The Effect of Patient Education Based on Nursing Model on Life Activities and Self-Care of Hemodialysis Patients
Chronic Renal Failure (CRF); The result of a decrease in the glomerular filtration value is defined as a chronic and progressive deterioration in the fluid-solute balance of the kidney and metabolic-endocrine functions.
- Trial name
- NCT04797234
- Testing
- Control, Experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Restless Legs Syndrome (RLS), End-Stage Renal Disease
Effect of Intra-Dialytic Muscle Energy Technique on Restless Leg Syndrome in Hemodialysis Patients
The goal of this clinical trial is to learn if intra-dialytic Muscle Energy Technique (MET) can reduce symptoms of restless legs syndrome (RLS) in people with end-stage renal disease (ESRD) receiving maintenance hemodialysis.
- Trial name
- MET-RLS (NCT07748065)
- Testing
- Muscle Energy Technique, Routine Medical Treatment and Hemodialysis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Renal Failure
A Study of Cytokine and Inflammatory Markers in Patients With Chronic Renal Failure
We hope to study components within the blood that may predict success, failure or other associated complications in relation to the type of vascular access being used.
- Trial name
- NCT00565994
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Hemodialysis, Ischemia Preconditioning
Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease
The aim of our study is to evaluate the impact of repeated episodes of ischemic quenching on changes in blood pressure, heart rate and laboratory parameters of inflammation in patients with kidney diseases.
- Conditions
- Hemodialysis, Ischemia Preconditioning, Chronic Kidney Disease, Blood Pressure Disorders
- Trial name
- NCT07746102
- Testing
- Preconditioning with control ischemic episodes
- Where
- 2 sites in Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Kidney Failure, Chronic Therapy; Hemodialysis
A Single Ascending Dose Study of Soluble Ferric Pyrophosphate Administered Intravenously in Healthy Volunteers.
The purpose of this study is to determine the pharmacokinetics of fixed ascending doses of intravenously administered Soluble Ferric Pyrophosphate
- Trial name
- NCT01920854
- Testing
- soluble ferric pyrophosphate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Hemodialysis Complication
Difference Between Interval and Continous Intradialytic Exercise on Functional Capacity in Hemodialysis Patient
The goal of this study is to find out the effect of interval versus continous intradialytic training on muscle quality index and functional capacity in Hemodialysis patients.
- Trial name
- NCT05722496
- Testing
- Aerobic pedaling exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Renal Dialysis
Pain Perception by the Chronic Renal Patient at the Time of Vascular Access Cannulation.
Pain in patients under hemodialysis affects chronic renal patients' quality of life. Distraction has been effective in controlling pain induced by the insertion of needles.
- Trial name
- NCT05729113
- Testing
- Distraction technique
- Where
- Portugal
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Joana Sofia Dias Pereira de Sousa
End Stage Kidney Disease
Phenotyping Seroconversion Following Vaccination Against COVID-19 in Patients on Haemodialysis Study
Patients on haemodialysis are at higher risk of getting a severe form of COVID-19 if they become infected. Vaccinations are soon to arrive and offer great hope of controlling the current pandemic.
- Trial name
- NCT04815850
- Where
- United Kingdom
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Chronic Kidney Disease Requiring Chronic Dialysis
Activation of the Contact System and the Immune System in Patients With Chronic Kidney Disease.
Patients with end-stage renal disease undergoing hemodialysis (HD) are burdened with extremely high mortality rates (15% per year) and during the early stage (≤120days) the mortality rate is even higher (27% per year).
- Trial name
- AKIM-CKD (NCT05266092)
- Testing
- Observational study
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital