Clinical trials: Hair Condition
Alopecia Areata(AA)
Impact of NR3C1 rs41423247 (BclI) Polymorphism on Disease Severity in Alopecia Areata
Alopecia areata is an autoimmune, non-scarring hair loss disorder with multifactorial pathogenesis. The glucocorticoid receptor gene (NR3C1) plays an essential role in immune regulation and inflammatory response.
- Trial name
- NR3C1 and AA (NCT07455708)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Atopic Dermatitis, Alopecia Areata
Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome
This is a single-center, open-label, basket phase 2b trial that will enroll Down Syndrome (DS) participants with at least one inflammatory skin condition (Atopic Dermatitis (AD) and/or Alopecia Areata (AA)).
- Trial name
- NCT07242638
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alopecia Areata, Alopecia Totalis
Phase 2 Trial of BNZ-1 in Patients With Moderate to Severe Alopecia Areata
This study is a randomized, double-blind, placebo-controlled, multi-center, dose-ranging study to characterize the efficacy and safety of BNZ-1 administered by slow IV push weekly for 3 months to adults diagnosed with moderate to…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis
- Trial name
- NCT03532958
- Testing
- BNZ-1, Normal saline
- Sponsor
- Equillium
Alopecia Areata
A Study of Secukinumab for the Treatment of Alopecia Areata
Alopecia areata is a medical condition, in which the hair falls out in patches. The hair can fall out on the scalp or elsewhere on the face and body.
- Trial name
- NCT02599129
- Testing
- Secukinumab
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hair Loss/Baldness, Alopecia
Autologous Adipose-Derived Adult Stromal Vascular Cell Transplantation for Alopecia
Most common forms of hair loss (alopecia) are caused by aberrant hair follicle cycling and changes in hair follicle morphology. However, current treatments for alopecia do not specifically target these processes.
- Trial name
- A-ADSVC-CT-A (NCT03427905)
- Testing
- Lipoaspiration, Transplantation
- Where
- Lebanon
- Volunteers
- 20 people
- Sponsor
- Lebanese University
Telogen Effluvium
Efficacy and Safety of Millet Seed Extract in Telogen Effluvium Treatment
This is a randomized, double-blind, controlled clinical trial investigating the efficacy and safety of millet seed extract capsules in treating telogen effluvium in female patients.
- Trial name
- NCT07348120
- Testing
- Millet Seed Extract group, Biotin group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Alopecia, Male Pattern Hair Loss
To Evaluate Efficacy, Safety, and Tolerability of KX-826 in Male Subjects With Androgenetic Alopecia
The study is a randomized, double-blind, placebo-controlled, parallel group, phase 2 study to evaluate the efficacy, safety and tolerability of KX-826 in male subjects with androgenetic alopecia.
- Trial name
- NCT05218642
- Testing
- KX- 826 dosed at 2.5mg, KX-826 dosed at 5mg
- Where
- 10 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
Breast Cancer, Chemotherapy-induced Alopecia
PBMT for the Management of CIA ( HAIRLASER )
Chemotherapy (CT) remains an important treatment modality for breast cancer patients. Unfortunately, this systemic treatment comes with many quality of life impairing complications.
- Conditions
- Breast Cancer, Chemotherapy-induced Alopecia, Alopecia
- Trial name
- NCT04036994
- Testing
- Photobiomodulation therapy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Substance Abuse
Hair Testing to Assess Consumption of Illicit Psychotropic Agents and Alcohol by Patients Treated With High-dose Buprenorphine and Methadone. Search for a Pharmacogenetic Contribution to Low Efficacy of Substitution Medications
Justification and aims of the study: The principal aim of use of opiate substitutes such as methadone or high-dose buprenorphine (HDB) is to reduce the need or the desire to consume the opiate to which the patient is addicted.
- Trial name
- NCT01285856
- Testing
- hair and saliva samples
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Androgenetic Alopecia (AGA)
Clinical Study of PRP in the Treatment of Androgenetic Alopecia
A study on the therapeutic effect of platelet-rich plasma in the treatment of androgenetic alopecia
- Trial name
- NCT07551271
- Testing
- PRP
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Trichotillomania
Cognitive Training in Patients With Trichotillomania (Hair-pulling Disorder)
The principal aim of this study is to establish the impact of Cognitive Training in patients with primary Hair-pulling Disorder.
- Trial name
- CTTTM (NCT02794753)
- Testing
- Working memory training, Game
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- University of Stellenbosch
Primary Breast Cancer
Comparative Study of Scalp Cooling System and Chemical Cold Cap (COHAIR Study)
This is a phase III, single-center, prospective, open-label, randomized,controlled study
- Trial name
- COHAIR (NCT03711877)
- Testing
- Scalp cooling system, Cold cap
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Tao OUYANG
Cushing Disease
Hair Cortisol and Cushing's Disease
The biochemical tools usable to assess the control of hypercortisolism in patients with Cushing's disease receiving medical treatments are debatable.
- Trial name
- HAIRCUSH (NCT04201444)
- Testing
- Patient group, Remission control group, Bilateral surrenalectomy control group
- Where
- 7 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Androgenic Alopecia, Alopecia
Effectiveness of Ultrapulse for the Treatment of Androgenic Alopecia Among Malaysian: A Quasi-experimental Study
The goal of this study is to to evaluate the effectiveness of Ultrapulse for the treatment of androgenic alopecia among Malaysian.
- Trial name
- NCT06292533
- Testing
- Er:YAG laser
- Where
- Malaysia
- Volunteers
- 92 people
- Sponsor
- Universiti Tunku Abdul Rahman
Androgenetic Alopecia (AGA)
To Evaluate Efficacy and Safety of TopicalKX-826 Solution in Chinese Male Patients With Androgenetic Alopecia
This study is a multicenter, randomized, double-blind, vehicle controlled, adaptive design phase 2/3 study to evaluate the efficacy and safety of topical KX-826 solution in Chinese male patients with androgenetic alopecia (AGA).
- Trial name
- NCT06622824
- Testing
- KX-826 0.5% BID, KX-826 1.0% BID
- Where
- China
- Volunteers
- 756 people
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
Baldness
Impact of Low-Level Laser Therapy on Hair Regrowth Post PRP Treatment
Low-level laser stimulates cells in the hair follicles, which promotes hair growth. The patient's own blood platelets are used in platelet-rich plasma treatment to encourage hair growth.
- Trial name
- NCT07048626
- Testing
- PRP treatment, low level laser therapy post prp treatment
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Superior University
Alopecia Areata, Alopecia Universalis
ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Universalis (AU) and Alopecia Totalis (AT)
This is an open label study of ATI-502 Topical Solution for the treatment of AA, AU, and AT with the following goals: To assess the safety, tolerability, and efficacy of ATI-502 Topical Solution in subjects with AA, AU or AT…
- Conditions
- Alopecia Areata, Alopecia Universalis, Alopecia Totalis
- Trial name
- NCT03759340
- Testing
- ATI 502 0.46% Topical Solution
- Where
- 20 sites in United States
- Volunteers
- 56 people
- Sponsor
- Aclaris Therapeutics, Inc.
Male Pattern of Hair Loss, Androgenic Alopecia
Minoxidil 5% / Botanical Hair Regimen in Men With Thinning Hair and Male Pattern Hair Loss/Androgenic Alopecia
The purpose of this study is to characterize the effect of Minoxidil 5% Foam and Botanical Hair Solution Regimen in men with thinning hair and male pattern hair loss/androgenic alopecia (Norwood III \& IV).
- Trial name
- NCT02460289
- Testing
- Treatment: Minoxidil 5% / Botanical Hair Solution for Men
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Galderma R&D
Alopecia Areata
Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.
To compare the efficacy and safety of topical pentoxifylline 2% gel and topical metformin 10% gel versus topical betamethasone valerate 0.1% cream, in treatment of patchy alopecia areata.
- Trial name
- NCT06087796
- Testing
- Betamethasone Valerate 0.1% Cream, Pentoxifylline, Metformin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Dihydrotestosterone, Testosterone
Influence of Creatine Monohydrate Supplementation on Androgens and Global Hair Assessments
This study is a randomized, double-blind, placebo-controlled trial examining the effects of creatine monohydrate supplementation on androgens and hair loss in free-living adult males.
- Conditions
- Dihydrotestosterone, Testosterone, Hair Loss
- Trial name
- NCT04298840
- Testing
- Creatine Monohydrate Supplementation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University