Clinical trials: Hallucinations
Schizophrenia, Schizoaffective Disorder
Quantifying Abnormalities in Cortical Activation Associated With Auditory Hallucinations Using Functional Magnetic Resonance Imaging
The goal of the project is to characterize abnormalities in brain structure and function related to schizophrenia. The investigators will use advanced magnetic resonance imaging (MRI) techniques to measure the degree and…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Hallucinations
- Trial name
- NCT00288340
- Testing
- functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Schizophrenia
Brain Stimulation, Clinical Symptoms and Cognition
The purpose of this study is to test the impact of non-invasive brain stimulation, transcranial direct current stimulation (tDCS), on auditory hallucinations, negative symptoms and cognition in schizophrenia.
- Trial name
- NCT05053451
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Schizophrenia
Effect of Repetitive Transcranial Magnetic Stimulation on Resting State Brain Activity in Schizophrenia
This study compares the efficacy of low and high frequency repetitive transcranial magnetic stimulation (rTMS) as a means of treating subjects with schizophrenia. Magnetic pulses delivered over the scalp cause brain activity.
- Trial name
- NCT01620086
- Testing
- Active Repetitive Transcranial Magnetic Stimulation 1 Hz, Active Repetitive Transcranial Magnetic Stimulation 10 Hz, Active control site Repetitive Transcranial Magnetic Stimulation at 1Hz
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Lewy Body Disease, Lewy Body Dementia
Visual Hallucinations in Lewy Body Diseases
The goal of this basic experimental study involving humans (BESH) protocol is to improve the understanding of neural mechanisms underlying visual hallucinations in Lewy Body diseases to inform future treatment developments.
- Conditions
- Lewy Body Disease, Lewy Body Dementia, Parkinson Disease, Parkinson Disease Dementia
- Trial name
- NCT07849413
- Testing
- Behavioral Tasks, MRI/MEG Scans
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hallucinations, No Hallucinations
Understanding Hallucinations (Part I)
Psychotic symptoms (hallucinations and delusions) are present in several psychiatric and neurological disorders as well as in the general population.
- Trial name
- UH-1 (NCT01907568)
- Where
- 4 sites in Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Nurses, Schizophenia Disorder
The Effectiveness of Combining AR/VR Technology in Virtual Clinical Auditory Hallucinations on the Comprehensive Auditory Hallucination Nursing Competency of Psychiatric Nurses
This study aims to develop and evaluate a Virtual Reality (VR) Auditory Hallucination Program to enhance psychiatric nurses' comprehensive care competence in managing auditory hallucinations among patients with schizophrenia.
- Conditions
- Nurses, Schizophenia Disorder, Hallucinations, Auditory
- Trial name
- NCT06938997
- Testing
- Virtual clinical auditory hallucination solution combining AR/VR technology, Auditory Hallucination Care Video
- Where
- 4 sites in Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Healthy
Neuronal Correlates of Altered States of Consciousness
The aim of the present study is to assess the neuronal correlates of alterations in waking consciousness pharmacologically induced by a 5-hydroxytryptamine (HT)2A receptor agonist in healthy subjects using functional magnetic…
- Trial name
- 5HT2A-fMRI (NCT02308969)
- Testing
- LSD
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Schizophrenia, Caregiver Burden
Effect of Simulation on Emotional Expression and Perceived Family Burden of Caregivers
The aim of this study is to determine the effect of Auditory Hallucination Based Voice Hearing Simulation on the emotional expression and perceived family burden of caregivers of individuals diagnosed with schizophrenia.
- Conditions
- Schizophrenia, Caregiver Burden, Expressed Emotion
- Trial name
- NCT06723977
- Testing
- Auditory Hallucination Based Voice Hearing Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Schizophrenia
Auditory Verbal Hallucinations in Schizophrenia
Auditory verbal hallucinations (AVHs) are speech perceptions in the absence of a relevant external stimulation. Some accounts of AVHs claim that a deficit in inner speech monitoring would cause the verbal thoughts of the patient…
- Trial name
- HAV (NCT01886417)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Schizophrenia, Hallucinations
Changes in Auditory Verbal Hallucination During Atypical Antipsychotic Treatment of Patients With Schizophrenia
The purpose of this study is to evaluate the changes in various aspects of auditory verbal hallucinations during 24-week antipsychotic treatment in naturalistic condition.
- Trial name
- NCT00328952
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Schizophrenia, Visual Hallucination
Visual Information Processing in Schizophrenia Patients With Visual Hallucinations
Occurrence of visual hallucinations (VHs) in schizophrenia depend in part on disorders in the processing of late visual information (Top-Down).
- Conditions
- Schizophrenia, Visual Hallucination, Auditory Hallucination, False Perception
- Trial name
- SHALL (NCT03188133)
- Testing
- behavioral task : emotional priming
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Medical Education, Generative Artificial Intelligence
Teaching Medical Students to Verify AI-Generated Citation Hallucinations
Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors.
- Trial name
- SARA (NCT07844746)
- Testing
- SARA Citation-Verification Training, Responsible GenAI Education Intervention Description
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam Medical College
Hallucinations, Verbal Auditory
Symptom Based Treatment Affects Brain Plasticity - the Role of Verbal Auditory Hallucinations
The aim of the study is the examination of brain plasticity on verbal auditory hallucinations (AVH) after neuromodulation with fMRI (functional magnetic resonance imaging) neurofeedback.
- Trial name
- APIC-II (NCT02722915)
- Testing
- fMRI, Neurofeedback, PANAS
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Schizophrenia
A Study on the Brain Mechanism of cTBS in Improving Medication-resistant Auditory Hallucinations in Schizophrenia
This study is dedicated to exploring the brain mechanism of medication-resistant auditory hallucinations and developing effective treatment methods for them by using both cross-sectional and longitudinal designs.
- Trial name
- NCT05039489
- Testing
- Antipsychotic drugs, cTBS（the left temporoparietal cortex as the stimulation target）, cTBS （the left cerebellum Crus II as the stimulation target）
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Randomized Controlled Trial
Enhancing Psychiatric Nursing Skills in Auditory Hallucination Assessment Via AR/VR and Virtual OSCE
The purpose of this study is to develop and evaluate AI-based virtual reality teaching resources aimed at enhancing nursing students' competencies in assessing, communicating with, and managing patients experiencing auditory…
- Trial name
- NCT06605781
- Testing
- AR/VR technology-based training, traditional vedio and discussion group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Auditory Hallucination, Verbal
Effects of Transcranial Direct Current Stimulation (tDCS) on Persistent Auditory Verbal Hallucinations in Schizophrenia
Many individuals with schizophrenia struggle with auditory verbal hallucinations (AVHs). In some cases, these AVHs can be resistant to medication treatment.
- Trial name
- NCT04222582
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Schizophrenia
TDCS for Auditory Hallucinations in Schizophrenia
The purpose of the present research is to test a potential new treatment for auditory verbal hallucinations in schizophrenia that uses transcranial Direct Current Stimulation (tDCS), a neurostimulation technique that passes an…
- Trial name
- NCT01898299
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Schizophrenia, Schizophreniform Disorders
Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants
The purpose of this trial is to study the effect of adding the omega-3 fatty acid EPA and/or Vitamins E + C to antipsychotic drugs in younger patients with schizophrenia and related psychoses.
- Conditions
- Schizophrenia, Schizophreniform Disorders, Schizoaffective Disorder, Psychotic Disorders
- Trial name
- NCT00419146
- Testing
- Ethyl-eicosapentaenoic acid (EPA), Vitamins E + C
- Where
- Norway
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aker
Dissociation, Auditory Hallucination
Psychological Therapy for Dissociation, Trauma and Voices: A Single Case Experimental Design
Connection to Environment with Cognitive Therapy (CONNECT): A Single-Case Experimental Design Exploring Dissociative Experiences and Voices Emerging empirical evidence has suggested that dissociation is a robust determinant of…
- Conditions
- Dissociation, Auditory Hallucination, Trauma, Psychological, Psychosis
- Trial name
- CONNECT (NCT04127526)
- Testing
- Connection to Environment with Cognitive Therapy (CONNECT)
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Schizophrenia, Parkinson Disease
Sound and Vision: A Collaboration Between Service-users, Artists and the Public to Explore the Lived Experience of Hallucinations
Sound and Vision: A collaboration between service-users, artists and the public to explore the lived experience of hallucinations
- Conditions
- Schizophrenia, Parkinson Disease, Hallucinations
- Trial name
- NCT04399096
- Where
- 2 sites in United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Cambridge