Clinical trials: Hallucinations, open to volunteers
Schizophrenia, Hallucinations, Auditory
Role of Inferior Colliculi in Auditory Hallucinations
The neural basis of auditory hallucinations (AH) in patients with schizophrenia is poorly characterized. Functional imaging studies investigate either the "state" dimension (i.e., the measurement of changes in brain area…
- Trial name
- SchizoHIC (NCT07003529)
- Testing
- Unenhanced brain MRI
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Schizophrenia, Auditory Hallucination
Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication…
- Conditions
- Schizophrenia, Auditory Hallucination, Treatment-resistant Schizophrenia
- Trial name
- NCT05299749
- Testing
- stg-rt-fMRI-Neurofeeback
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Boston VA Research Institute, Inc.
Schizophrenia, Transcranial Magnetic Stimulation
Evaluation of the Efficacy of Transcranial Magnetic Stimulation on Resistant Auditory Hallucinations in Schizophrenia
This open naturalistic study aims to evaluate the efficacy of rTMS in routine practice on auditory resistant hallucinations (AHR) of patients with schizophrenia.
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Hallucinations, Verbal Auditory
- Trial name
- HRRENAT (NCT06599372)
- Testing
- The rTMS method, The cTBS method
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Dominique JANUEL
Psychotic Disorders, Hallucinations, Auditory
Testing a Peer-Support Group for Veterans Who Hear Voices
Veterans with schizophrenia spectrum disorders who experience psychosis struggle with social integration- e.g., participation in work, housing, and citizenship-due to symptoms, stigma, and psychosocial functioning deficits.
- Conditions
- Psychotic Disorders, Hallucinations, Auditory, Social Isolation
- Trial name
- VVV RCT (NCT07555275)
- Testing
- Veteran Voices and Visions (VVV), Wellness Recovery Action Planning (WRAP)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis
A Phase 1, MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LY03017
This is a phase 1，randomized, double-blind, placebo-controlled, MAD study to evaluate the safety, tolerability and pharmacokinetics of oral LPM526000133 Fumarate Capsules (LY03017) in healthy adult subjects
- Conditions
- Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis, Negative Symptoms of Schizophrenia
- Trial name
- NCT06980207
- Testing
- LY03017
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Schizophrenia, Auditory Verbal Hallucinations
Neuronavigated rTMS for Treatment-Resistant Auditory Hallucinations
Auditory verbal hallucinations (AVH), such as hearing voices in the absence of an external sound source, are a common and distressing symptom of schizophrenia.
- Trial name
- fuNEEG (NCT07856368)
- Testing
- Neuronavigated repetitive transcranial magnetic stimulation (rTMS)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Psychiatric University Hospital, Zurich
Parkinson's Disease Psychosis, Dementia With Lewy Bodies
Comparing Antipsychotic Medications in LBD Over Time
The primary objective of this study is to determine whether treatment with pimavanserin or quetiapine is associated with a greater improvement in psychosis when used in a routine clinical setting to treat hallucinations and/or…
- Trial name
- CAMELOT (NCT05590637)
- Testing
- Pimavanserin, Quetiapine
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Auditory Hallucinations, Schizophrenia Spectrum
Cost-utility Study of Cognitive-behavioral Management of Auditory Hallucinations in Schizophrenic Disorder
The aim of the study is to assess the effectiveness and costs of a cognitive-behavioral treatment (CBT) for auditory hallucinations (psychotherapy) as an adjunct to usual care, comparing it to the effectiveness and costs of usual…
- Trial name
- VOICES (NCT07134816)
- Testing
- Cognitive and behavioral therapy for auditory hallucinations, Usual treatment
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Montpellier
Hallucinations, Auditory
The ECHO Study: Compassion-focused Therapy for Young Voice Hearers and Their Caregivers
In this project, a 10-session treatment program was developed aimed at young people who experience voice hearing. The treatment has potential to easily be implemented in everyday clinical practice in Child and Adolescent…
- Trial name
- ECHO (NCT07314515)
- Testing
- ECHO Manualized CFT treatment for young voice heares
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Medical Education, Generative Artificial Intelligence
Teaching Medical Students to Verify AI-Generated Citation Hallucinations
Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors.
- Trial name
- SARA (NCT07844746)
- Testing
- SARA Citation-Verification Training, Responsible GenAI Education Intervention Description
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam Medical College
Schizophrenia, Auditory Hallucinations
LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI)
Individuals with schizophrenia often experience persistent auditory hallucinations despite treatment with antipsychotic medications.
- Trial name
- MESSI-LEO (NCT07710989)
- Testing
- LIFU
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Schizophrenia, Schizo Affective Disorder
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia.
- Trial name
- NCT05343598
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Mclean Hospital
Psychosis Associated With Alzheimer's Disease
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
ML-007C-MA-221 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ML-007C-MA in male and female participants aged 55 to 90 years with hallucinations and delusions associated…
- Trial name
- NCT06887192
- Testing
- ML-007C-MA
- Where
- 62 sites in United States, Argentina and 13 more
- Volunteers
- 300 people
- Sponsor
- MapLight Therapeutics
Schizophrenia Disorder, Schizoaffecitve Disorder
DecNef for Auditory Verbal Hallucinations (AVH) in Schizophrenia
The purpose of this study is to learn whether a research neurofeedback training approach done during MRI scans may help reduce hallucinations such as the experience of hearing voices persistent despite treatment.
- Trial name
- DecNef (NCT07779226)
- Testing
- Decoded Neurofeedback
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Columbia University
Alzheimer's Disease Psychosis
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
This 52-week, open-label extension study is to evaluate the long-term safety and tolerability of ACP-204 in subjects with ADP.
- Trial name
- NCT06194799
- Testing
- ACP-204
- Where
- 78 sites in United States, Brazil and 10 more
- Volunteers
- 752 people
- Sponsor
- ACADIA Pharmaceuticals Inc.