Clinical trials: Hand Dermatitis
Chronic Hand Dermatitis
Apremilast and Moderate to Severe Chronic Hand Dermatitis
Investigators have designed a pilot study involving chronic hand dermatitis (CHD) patients who attend the dermatology clinic at the George Washington Medical Faculty Associates (GW MFA) in order to assess the efficacy and safety…
- Trial name
- CHD (NCT03741933)
- Testing
- Apremilast 30mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- George Washington University
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema
This was a 16-week study in adult participants with chronic hand eczema (CHE). > The participants visited the clinic regularly to have the study doctor assess their CHE and to answer questions about itch, pain, CHE symptoms, and…
- Trial name
- DELTA 1 (NCT04871711)
- Testing
- Delgocitinib cream, Cream vehicle
- Where
- 54 sites in Canada, France and 4 more
- Volunteers
- 487 people
- Sponsor
- LEO Pharma
Hand Dermatoses
Safety and Efficacy Study of Triamcinolone Acetonide DuraPeel to Treat Hand Dermatitis
The purpose of this study is to determine whether Triamcinolone Acetonide (TAC) DuraPeel is safe and effective in the treatment of hand dermatitis.
- Trial name
- TAC-202 (NCT00890968)
- Testing
- Triamcinolone Acetonide (TAC) DuraPeel
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- ZARS Pharma Inc.
Palmar and Plantar Erythema, Numbness of the Four Limbs
Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome
This study is a prospective, single-center, randomized, parallel-group, open-label clinical trial titled "Intervention with the 'Xu Xue Tong Luo Traditional Chinese Medicine Compound for Capecitabine-Related Hand-Foot Syndrome."…
- Conditions
- Palmar and Plantar Erythema, Numbness of the Four Limbs, Pain in the Distal Extremities, Peeling of the Soles and Palms
- Trial name
- NCT07883642
- Testing
- Twelve-Ingredient Prepared Sichuan Aconite Hand and Foot Bath, Standard Basic Nursing Interventions
- Volunteers
- 7 people
- Sponsor
- Emeishan Hospital of Traditional Chinese Medicine
Occupational Contact Dermatitis
Occupational Hand Eczema - Testing of a Prevention-concept
Randomised controlled trial examining the effect of decreased waiting time for the first doctors' appointment, patient education, glove counselling and counselling at departments of social or occupational medicine on severity of…
- Trial name
- NCT04790799
- Testing
- Treatment at the skin department at Gentofte Hospital
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- National Allergy Research Center, Denmark
Palmar-Plantar Erythrodysesthesia, Breast Cancer
Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome
The purpose of this research study is to see if combining uracil cream (UTC) with capecitabine (Xeloda) can prevent Hand-Foot Syndrome.
- Trial name
- NCT01100463
- Testing
- Cream, 0.1% Uracil Cream
- Where
- 6 sites in United States
- Volunteers
- 18 people
- Sponsor
- Nanometics (d.b.a. PHD Biosciences)
Patients With Solid Tumors
Traditional Chinese Medicine Hand-Foot Soak for Chemotherapy-Induced Peripheral Neuropathy and Hand-Foot Syndrome
Systemic therapies, including chemotherapy, targeted therapy, and immunotherapy, are cornerstones of modern oncology and have significantly extended patient survival.
- Trial name
- NCT07375446
- Testing
- Traditional Chinese Medicine
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Hand Dermatoses
Efficacy and Safety of a Retinoid for the Treatment of Severe Chronic Hand Dermatitis
The purpose of the study is to determine the therapeutic effect of alitretinoin, a retinoid, on severe, therapy refractory chronic hand dermatitis.
- Trial name
- NCT00124475
- Testing
- alitretinoin
- Where
- Germany
- Volunteers
- 1,035 people
- Sponsor
- Basilea Pharmaceutica
Eczema
Efficacy and Safety of a Retinoid in the Treatment of Severe Chronic Hand Eczema
The purpose of this study is to investigate the safety and efficacy of alitretinoin in the treatment of severe chronic hand eczema that does not respond to treatment with potent topical steroids.
- Trial name
- HANDEL (NCT00817063)
- Testing
- alitretinoin
- Where
- 70 sites in United States
- Volunteers
- 599 people
- Sponsor
- Stiefel, a GSK Company
Dermatitis, Chronic
Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis.
The purpose of this study is to determine how clobetasol proprionate foam works against a placebo foam in the treatment of hand dermatitis.
- Trial name
- NCT01323673
- Testing
- clobetasol propionate 0.05%
- Where
- 10 sites in United States
- Volunteers
- 125 people
- Sponsor
- Stiefel, a GSK Company
Chronic Hand Eczema
Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema
The purpose of this research trial was to test different strengths of a new trial medication, delgocitinib cream 1, 3, 8, and 20 mg/g, and to investigate how treatment with delgocitinib cream affects chronic hand eczema.
- Trial name
- NCT03683719
- Testing
- Delgocitinib cream, Delgocitinib cream vehicle
- Where
- 28 sites in United States, Denmark and 1 more
- Volunteers
- 258 people
- Sponsor
- LEO Pharma
Hand and Foot Syndrome
TAR-0520 Gel in Hand and Foot Syndrome
Hand and Foot Syndrome (HFS) is a weii-established and frequent cutaneous adverse event of capecitabine used in the treatment of different cancers.HFS is charectirized by a variety of symptoms ranging from mild discomfort to a…
- Trial name
- TARIAN008 (NCT07457671)
- Testing
- TAR-0520 gel
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Tarian Pharma
Chronic Hand Eczema (CHE)
Real-World Evidence: Effectiveness and Safety of Chronic Hand Eczema Treatment With Delgocitinib Cream
The goal of this non-interventional study is to assess changes in the signs and symptoms of Chronic Hand Eczema (CHE), as well as the safety profile and use of delgocitinib cream in routine clinical practice, over a 52-week…
- Trial name
- REACHED (NCT07603193)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- LEO Pharma
Atopic Hand and Foot Dermatitis
A Study to Investigate the Efficacy and Safety of Lebrikizumab in Participants With Moderate-to-Severe Atopic Hand and Foot Dermatitis
The main purpose of this study is to assess the efficacy of lebrikizumab versus placebo on skin lesions in adults and adolescent participants with atopic hand and foot dermatitis.
- Trial name
- ADtouch (NCT06921759)
- Testing
- Lebrikizumab
- Where
- 76 sites in United States, Argentina and 6 more
- Volunteers
- 221 people
- Sponsor
- Eli Lilly and Company
Hand Eczema
A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema
The purpose of this study is to investigate whether a moisturizing cream can prevent hand eczema.Patients with previous hand eczema will be studied.
- Trial name
- NCT00576550
- Testing
- Urea, betamethasone valerate
- Where
- 3 sites in Norway
- Volunteers
- 53 people
- Sponsor
- ACO Hud Nordic AB
Chronic Hand Eczema
Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema
This study will assess the safety and efficacy of ARQ-252 cream in subjects with chronic hand eczema
- Trial name
- NCT04378569
- Testing
- ARQ-252 cream 0.3%, ARQ-252 cream 0.1%, ARQ-252 Vehicle Cream
- Where
- 37 sites in United States, Australia and 1 more
- Volunteers
- 230 people
- Sponsor
- Arcutis Biotherapeutics, Inc.
Hand-foot Syndrome
Study of Pyridoxine for Hand-Foot Syndrome
Although pyridoxine has been used empirically for the prevention of capecitabine associated hand-foot syndrome (HFS), its efficacy needs to be demonstrated in prospective controlled trials.
- Trial name
- NCT00446147
- Testing
- Pyridoxine
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Palmar-Plantar Erythrodysesthesia Syndrome
Safety and Efficacy Placebo Controlled Study of ATH008 Cream in PPES Patients Secondary to Capecitabine
The aim of this study is to evaluate the safety and efficacy of ATH008 cream in patients with Palmar-Plantar Erythrodysesthesia Syndrome (PPES) secondary to capecitabine therapy.
- Trial name
- NCT01316406
- Testing
- ATH008
- Where
- 26 sites in Belgium, Germany and 2 more
- Volunteers
- 122 people
- Sponsor
- Advancell - Advanced In Vitro Cell Technologies, S.A.
Hand Dermatosis
Study to Evaluate Safety, Efficacy and Tolerability of Clobetasol Propionate for Chronic Hand Dermatitis
The purpose of the study is to assess the safety, efficacy and tolerability of Clobetasol propionate foam in subjects with chronic dermatitis.
- Trial name
- NCT00828464
- Testing
- clobetasol propionate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stiefel, a GSK Company
Eczema
Paraffin Bath Therapy for Chronic Hand Eczema
Objective: Chronic Hand eczema (CHE) is a common inflammatory skin disease has a major medical psychological and socio-economic implications that affect quality of life (QoL)and work ability.
- Trial name
- NCT04510961
- Testing
- Paraffin baths therapy
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University