Clinical trials: Hand Dermatoses
Scleroderma, Scleroderma, Systemic
Effectiveness of Telerehabilitation on Scleroderma
The effects of exercises performed by telerehabilitation on individuals with hand-affected scleroderma on range of motion, grip strength, function, sensation, daily life activities and general health will be compared with the…
- Conditions
- Scleroderma, Scleroderma, Systemic, Scleroderma Associated Digital Ulcer, Hand Rheumatism
- Trial name
- NCT04563481
- Testing
- Hand Therapy via Telerehabilitation, Hand Therapy by Physiotherapist
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Colorectal Cancer, Metastases
S-1 Versus Capecitabine in the First Line Treatment of MCC Patients.
The study is a two-arm randomised phase III trial. Patients will be randomised to receive capecitabine (arm A) or S-1 (arm B). Bevacizumab may be added according to the choice of the investigator.
- Trial name
- SALTO (NCT01918852)
- Testing
- Capecitabine, Teysuno, Bevacizumab
- Where
- 24 sites in Netherlands
- Volunteers
- 161 people
- Sponsor
- Dutch Colorectal Cancer Group
Hand and Foot Syndrome, Erythrodysesthesia Syndrome
Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal Cancer
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of malignancy-related mortality. Capecitabine has been approved for the treatment of colorectal cancer as first-line therapy.
- Conditions
- Hand and Foot Syndrome, Erythrodysesthesia Syndrome, HFS, Colorectal Cancer
- Trial name
- HFS (NCT05327751)
- Testing
- Celecoxib 200mg, Capecitabine-based chemotherapy
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Ovarian Neoplasm
DOXIL for Consolidation Therapy in Ovarian Cancer.
The primary objective for this study is to evaluate the development, frequency and severity of hand foot syndrome (HFS) in ovarian cancer subjects treated with Doxil®, as consolidation therapy, on an every two week schedule.
- Trial name
- NCT00248248
- Testing
- liposomal doxorubicin
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Southeastern Gynecologic Oncology
Palmar-plantar Erythrodysesthesia
Topical Antiperspirant for Hand-Foot Syndrome
The objectives of this study are to evaluate the effectiveness of an antiperspirant in preventing or attenuating the severity of palmer-plantar erythrodysesthesia associated with the Food and Drug Administration (FDA)-approved…
- Trial name
- NCT00213993
- Testing
- antiperspirant
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Wisconsin, Madison
Actinic Keratosis
Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses
Actinic keratoses (AK) are common cutaneous lesions associate with chronic ultraviolet radiation exposure. While most authorities consider AK as a pre-malignant lesion, some consider it as an incipient squamous cell carcinoma…
- Trial name
- NCT01229319
- Testing
- Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Frankel, Amylynne, M.D.
Wounds, Diabetic Foot Ulcers
Evaluation of a 'Hand-held' Fluorescence Digital Imaging Device for Real-Time Advanced Wound Care Monitoring (JDRTC/UHN)
We have developed an innovative optical molecular imaging platform (called PRODIGI) based on high-resolution fluorescence and white-light technologies in a hand-held, real-time, high-resolution, non-invasive format.
- Trial name
- JDRTC/UHN (NCT01651845)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University Health Network, Toronto
Scleroderma
Scleroderma Treatment With Celution Processed ADRCs Registry
This registry study will assess the safety and performance of the Celution Device in the processing of an autologous graft consisting of adipose derived regenerative cells (ADRCs) in the treatment of hand scleroderma.
- Trial name
- STAR (NCT02328625)
- Sponsor
- Cytori Therapeutics
Hand Eczema, Foot Eczema
Treatment of Staphylococcus Aureus Colonization in Hand Eczema
Atopic dermatitis is a chronic disease characterized by itching and eczematous lesions. In adults, eczema commonly localizes to the hands or feet.
- Trial name
- NCT01591785
- Testing
- Retapamulin 1% ointment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Gary Goldenberg
Psoriatic Arthritis
Comparison of Hand Functions and Wrist Proprioception in Patients With and Without Psoriatic Arthritis
The purpose of this study is to assess hand functions and wrist joint position sense in patients with and without PsA.
- Trial name
- NCT04553302
- Testing
- This study does not contain any intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Melissa Köprülüoğlu
Solid Cancer, Gastric (Cardia, Body) Cancer
Impact of CES1 Genotype on Capecitabine Exposure in Cancer Patients
In this study, the drug capecitabine is investigated. Capecitabine is commonly used to treat breast, colon, and stomach cancers. Capecitabine is taken in tablet form.
- Conditions
- Solid Cancer, Gastric (Cardia, Body) Cancer, Esophageal Cancer, Colorectal Cancer (CRC)
- Trial name
- ESCAPE (NCT07114627)
- Testing
- Blood sampling for pharmacokinetics
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Erasmus Medical Center
Hand and Foot Syndrome
Vitamin B6 Can Prevent Hand and Foot Syndrome in Cancer Patients Capecitabine Chemotherapy
Capecitabine (Xeloda) a drug in cancer therapy. Its use is limited often by its toxicities. This study is asking if vitamin B6 can prevent one of the common toxicities of xeloda which is numbness and/or rash of the hands and…
- Trial name
- NCT00767689
- Testing
- Vitamin B 6
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cook County Health
Breast Cancer
Effects of Hands-on-Healing vs. Touch for Fatigued Breast Cancer Survivors
This randomized controlled trial examines the efficacy of hands-on-healing for fatigue and immune function in breast cancer survivors.
- Trial name
- NCT00440089
- Testing
- Hands-on-Healing
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- University of California, San Diego
Atopic Dermatitis
Ciclosporin Versus Alitretinoin for Severe Atopic Hand Dermatitis.
The purpose of this study is to investigate the comparative efficacy, safety and efficiency of ciclosporin microemulsion and alitretinoin in adults with severe atopic hand dermatitis.
- Trial name
- TocyDD (NCT01231854)
- Testing
- Ciclosporin, Alitretinoin
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Technische Universität Dresden
Viral Wart, Plantar Wart
Intralesional Therapies For Cutaneous Viral Warts: A Comparative Analysis Of Vitamin D3 And Acyclovir
The goal of this clinical trial is to learn if injecting acyclovir (an antiviral drug) or vitamin D3 directly into skin warts works to clear them in people aged 12 and older with common, plantar, flat, or periungual (around the…
- Conditions
- Viral Wart, Plantar Wart, Common Warts (Verruca Vulgaris), Common Wart
- Trial name
- NCT07448844
- Testing
- Intralesional Acyclovir, Intralesional Vitamin D3
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Breast Cancer, Breast Cancer Female
Factors Affecting Functionality in Breast Cancer Survivors
Breast cancer is the most frequent cancer type in women globally. In conjunction with the new developments, breast cancer survival has increased therefore the management of long-term complications has gained importance.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Cancer Lymphedema, Breast Carcinoma in Situ
- Trial name
- NCT04245657
- Testing
- Tissue Dielectric Constant Measurement, Muscle strength measurement, Hand-Grip Strength Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Izmir Bakircay University
Cancer
The Preventive Effect of Chemotherapy-induced Hand-foot Syndrome
this study will use traditional Chinese medicine bath with no obvious side effects combined with case tracking management mode to form nursing measures to prevent hand foot syndrome.
- Trial name
- NCT06441513
- Testing
- Chinese traditional medicine nursing combined with case tracking management, Health Education
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University Third Hospital
Dermatologic Complications, Palmar-plantar Erythrodysesthesia
Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer
RATIONALE: Pyridoxine may help prevent hand-foot syndrome caused by capecitabine in patients with cancer. It is not yet known whether pyridoxine is more effective than a placebo in preventing hand-foot syndrome in patients with…
- Conditions
- Dermatologic Complications, Palmar-plantar Erythrodysesthesia, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00486213
- Testing
- pyridoxine hydrochloride
- Where
- Singapore
- Volunteers
- 210 people
- Sponsor
- National Cancer Centre, Singapore
Systemic Sclerosis (SSc), Magnetic Resonance Imaging (MRI)
7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis
Systemic sclerosis (SSc) is a rare systemic autoimmune disease with specific osteoarticular pattern of unknown mechanism. Ischemic phenomenon have been suggested to participate to the osteoarticular involvement in SSc.
- Trial name
- PREM'S (NCT04223817)
- Testing
- 7.0 T RMI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Keratosis
Study to Assess the Safety and Efficacy of Imiquimod 5% Cream for the Treatment of Actinic Keratosis on the Arms and Hands
The purpose of this study is to evaluate the safety and efficacy of imiquimod 5% cream compared to vehicle cream in the treatment of Actinic Keratosis (AK) on the arm and/or hand when the cream is applied once daily 2 days per…
- Trial name
- NCT00115154
- Testing
- Aldara (imiquimod) cream, 5%
- Where
- 18 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Graceway Pharmaceuticals, LLC