Clinical trials: Hand Dermatoses
Scleroderma
Self-management Telehealth Program for Scleroderma
Scleroderma causes the skin on the hands to harden, causing the hands to contract, and the fingers to bend abnormally, which affect the patient's work and quality of life.
- Trial name
- NCT06990386
- Testing
- self-management program, Video guide and usual education, Telephone notification, video guide and usual education
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Khon Kaen University
Chronic Hand Dermatitis
Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema
Randomized double-blind/placebo study to evaluate the efficacy of ASN002 in subjects with severe chronic hand eczema.
- Trial name
- NCT03728504
- Testing
- ASN002
- Where
- 23 sites in United States, Canada
- Volunteers
- 97 people
- Sponsor
- Asana BioSciences
Raynaud Disease, Scleroderma, Systemic
Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.
The aim of the study is to determine if postocclusive hyperemia of palmar and dorsal face of the hand with Laser speckle contrast imaging discriminate between patients with systemic sclerosis, subjects with primary Raynaud's…
- Trial name
- SPECIES (NCT01743612)
- Testing
- laser speckle contrast imaging, Cooling
- Where
- 2 sites in France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Breast Cancer
Acupuncture Chemotherapy-Induced Peripheral Neuropathy (CIPN) IRG
The goal of this clinical research study is to compare the level of effectiveness for 2 acupuncture treatment schedules for chronic CIPN in breast cancer survivors.
- Trial name
- NCT01815346
- Testing
- Acupuncture, Questionnaires, Hand Function and Balance Tests
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Hand-foot Syndrome
The Efficacy and Safety of Mecobalamin in the Prevention of Capecitabine Induced Hand Foot Syndrome
A multicenter, randomized, placebo-controlled, double-blind, phase III clinical trial will be conducted to explore the efficacy and safety of mecobalamin in the prevention of 2/3 HFS in patients with early breast cancer.
- Trial name
- NCT05165069
- Testing
- Mecobalamin 5 MG Disintegrating Oral Tablet
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Vitiligo
Topical Psoralen Ultraviolet Light A Versus Narrow Band Ultraviolet Light B Treatment for Recalcitrant Dermatoses of the Hand
Hand psoriasis/eczema is a common problem which is characterized by itchy, erythematous and scaly lesions often with a long lasting and relapsing course.
- Trial name
- NCT01792245
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Palmar-Plantar Erythrodysesthesia, Palmar-Plantar Erythrodysesthesia Due to Cytotoxic Therapy
Efficacy and Safety of Moisturising Cream With or Without Vitamin E and Urea Cream in Palmar-plantar Erythrodysesthesia
This is a single-centre, phase II, three-arm, randomised controlled trial to evaluate the efficacy and safety of a cosmetic moisturising cream containing palm-oil-derived vitamin E concentrate or a similar moisturising cream…
- Trial name
- ECaPPE (NCT05939726)
- Testing
- Moisturising cream with vitamin E concentrate, Moisturising cream without vitamin E concentrate, Urea cream
- Where
- Malaysia
- Volunteers
- 145 people
- Sponsor
- Sarawak General Hospital
Hand-foot Skin Reaction, Rash
Sorafenib-induced Hand- Foot Skin Reaction Treatment
The purpose of this study is to evaluate treatments for a rash caused by sorafenib.
- Trial name
- NCT00667589
- Testing
- urea 40% cream, fluocinonide 0.05% cream, tazarotene 0.1% cream
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Northwestern University
Systemic Sclerosis
Evaluation of Calcinosis in Systemic Sclerosis
Systemic sclerosis is a rare pathology characterized by fibrosis and vascular lesion with skin, pulmonary, digestive and cardiac localisation.
- Trial name
- CALCIDERMIS (NCT03340194)
- Testing
- Radiography, Veinous punction
- Where
- France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Lille
Hand-foot Syndrome, Hand-foot Skin Reaction
Photobiomodulation Therapy in the Management of Hand-foot Syndrome and Hand-foot Skin Reaction
Hand-foot syndrome (HFS) is a side effect of chemotherapy. HFS is characterized by redness, swelling, and pain on the palms of the hands and/or soles of the feet, which can progress to blistering.
- Trial name
- DermLight (NCT04979078)
- Testing
- Photobiomodulation therapy (PBMT)
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Jessa Hospital
High Intensity Laser Therapy, Psoriasis
Efficacy of Pulsed High Intensity Laser Therapy in Psoriatic Hand Arthritis
The purpose of the study was to evaluate the therapeutic efficacy of pulsed high intensity level laser therapy in improving symptoms of psoriatic hand arthritis.
- Conditions
- High Intensity Laser Therapy, Psoriasis, Hand
- Trial name
- NCT06665282
- Testing
- Pulsed high intensity laser therapy, Routine physical therapy program
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Vesicular Palmoplantar Eczema, Pompholyx
Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema
Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema.
- Trial name
- NCT00442091
- Testing
- dandelion juice
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Odense University Hospital
Chronic Hand Eczema
A Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Delgocitinib Cream in Chinese Adults and Adolescents With Moderate to Severe Chronic Hand Eczema
The primary objective of this study is to evaluate the efficacy of twice-daily applications of delgocitinib cream 20 mg/g compared with cream vehicle in the treatment of participants with moderate to severe chronic hand eczema…
- Trial name
- NCT06004050
- Testing
- Delgocitinib, Vehicle cream
- Where
- 37 sites in China
- Volunteers
- 362 people
- Sponsor
- LEO Pharma
Dermatitis, Nevus
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
This study will evaluate whether digital photography is a reliable tool for diagnosing hand rashes, psoriasis and unusual moles.
- Conditions
- Dermatitis, Nevus, Psoriasis
- Trial name
- NCT00005781
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Hand and Foot Bath for Taxane-Induced Peripheral Neurotoxicity
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and dose-limiting toxicity of taxane-based agents, with an incidence of 57%-83%.
- Trial name
- NCT07344974
- Testing
- Traditional Chinese medicine (TCM) hand and foot baths, Methylcobalamin (methylB12)
- Volunteers
- 78 people
- Sponsor
- Peking University Cancer Hospital & Institute
Capecitabine, Hand-foot Syndrome
Electroacupuncture Combined With Self-administered Acupressure for the Prevention of Capecitabine-Associated Hand-Foot Syndrome
This study hypothesizes that electroacupuncture combined with self-administered acupressure plus doctor-prescribed treatment is effective in preventing Hand-Foot Syndrome (HFS) caused by capecitabine.
- Conditions
- Capecitabine, Hand-foot Syndrome, Electroacupuncture, Self-administered Acupressure
- Trial name
- NCT06602167
- Testing
- True electroacupuncture + True self-administered acupressure, Doctor-prescribed treatment
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Qinghai University
Actinic Keratoses, Carcinoma, Squamous Cell
Phase II AK Study in Organ Transplant Patients
The purpose of this study is to determine whether afamelanotide (CUV1647) is effective in reducing the number of actinic keratoses and squamous cell carcinomas developing in immune compromised organ transplant recipients, who are…
- Conditions
- Actinic Keratoses, Carcinoma, Squamous Cell, Organ Transplant Recipients
- Trial name
- NCT00829192
- Testing
- Afamelanotide (CUV1647)
- Where
- 12 sites in Australia, Belgium and 5 more
- Volunteers
- 200 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Atopic Dermatitis, Atopic Hand Eczema
A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy
The purpose of this study is to test if treatment with tralokinumab is safe and efficacious in treating moderate-to-severe atopic hand eczema.
- Trial name
- ADHAND (NCT05958407)
- Testing
- Tralokinumab
- Where
- 69 sites in United States, Belgium and 8 more
- Volunteers
- 235 people
- Sponsor
- LEO Pharma
Hand-foot Syndrome
The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients
Comparative analysis of the severity of Hand-Foot-Syndrome (HFS) of palms treated with brimonidine tartrate gel or with standard care Urea 10% containing lotion in cancer patients receiving antineoplastic therapy to show a…
- Trial name
- BRIMOCAN (NCT03173365)
- Testing
- Brimonidine Tartrate
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Diffuse Systemic Sclerosis
Serial Night Time Position Splint on Systemic Sclerosis
This is a randomized controlled trial with blinded evaluator and follow-up of one year. Seventy six patients with diffuse systemic sclerosis, will be randomized into two groups.The patients can not change their medication during…
- Trial name
- NCT01586663
- Testing
- Serial night time position splint, Drug treatment
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Federal University of São Paulo