Clinical trials: Hand Osteoarthritis
Osteoarthritis Hand, Neuropathic Pain
Capsaicin in Digital Osteoarthritis Versus Control
The objective of this multicentric, randomized controlled double-blind clinical trial is to demonstrate the efficacy of transdermal application of capsaicin in patients with painful digital osteoarthritis with a neuropathic pain…
- Trial name
- CADOR (NCT06444919)
- Testing
- Capsaicin 179 Mg Cutaneous Patch, Capsaicine low dose 0.04 %
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hand Osteoarthritis
Hand Osteoarthritis: Investigating Pain Trajectories and Association With Biomarkers Including Estrogen Cohort
Adults with painful hand osteoarthritis are invited to take part in this observational cohort study. The course of hand pain can vary and is not well understood - some people seem to have short episodes of worsening pain…
- Trial name
- HOPE-c (NCT05105854)
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Oxford
Polyarthritis
Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years. At present time,there is no effective treatment against digital arthritis.
- Trial name
- ADEM (NCT01068405)
- Testing
- Methotrexate
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hand Osteoarthritis
Acupuncture vs Sham Acupuncture for Hand Osteoarthritis
The investigators plan to conduct this multicentered, sham-controlled randomized clinical trial to evaluate the efficacy and safety of acupuncture for clinical symptomatic improvement of hand OA.
- Trial name
- NCT05267093
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Hand Osteoarthritis
The Hand Osteoarthritis Exercise Trial
The purpose of this study is to evaluate the effect of a hand exercise intervention on function and osteoarthritis symptoms in persons with hand osteoarthritis .
- Trial name
- NCT01245842
- Testing
- Hand exercise program
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Diakonhjemmet Hospital
Arthritis, Psoriatic, Hand Osteoarthritis
Central Pain Mechanisms in Patients With Hand-Osteoarthritis, Psoriatic Arthritis and Healthy Controls
In this trial different parts of the pain signalling system involved in two rheumatic diseases - painful hand osteoarthritis and psoriatic arthritis, is examined.
- Trial name
- NCT03703934
- Where
- Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Osteoarthritis Hand
S-Asenosyl-L-Methionine vs Placebo for Osteoarthritis of the Hands
The primary objective of this study is to demonstrate the feasibility of evaluating SAMe tolerability, analgesic benefits, and daily functional improvement in patients with osteoarthritis of the hands compared to placebo.
- Trial name
- SAMe (NCT05363020)
- Testing
- S-Adenosyl-L-Methionine (Sam-E)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Osteoarthritis Thumb
The Effects of Two Different Orthosis on Pain, Hand Strength and Function in Patients With Thumb Carpometacarpal Osteoarthritis
The investigators aimed to assess the effects of two different hand orthosis on hand functioning, pain, disability and quality of life in patients with thumb osteoarthritis
- Trial name
- NCT03327480
- Testing
- orthosis
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Thumb Osteoarthritis, Hand Osteoarthritis
Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis
One of the standard treatment methods in individuals with thumb osteoarthritis (OA) is exercise. Combination therapy options involving these exercises can be applied to patients.
- Trial name
- NCT07112742
- Testing
- High-Intensity Laser Therapy and Exercise, High-Intensity Laser Therapy at a Non-Therapeutic Dose Combined With Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- TC Erciyes University
Hand Osteoarthritis
Crystalline Glucosamine Sulfate Therapy in Hand Osteoarthritis
The objective of this study is to retrospectively evaluate the symptomatic effects of crystalline glucosamine sulfate (GS), prescribed for the actually approved indication of knee OA, in addition to conventional therapy, in…
- Trial name
- NCT03911570
- Testing
- Glucosamine Sulfate
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- University of Siena
Flexor Tendon Rupture, Thumb Osteoarthritis
Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
This will be a prospective randomized control trial with a blocking method to determine the effect of an occupational therapy focused pre-operative education on 3 pre-determined diagnosis: Carpometacarpal (CMC) Arthroplasty…
- Conditions
- Flexor Tendon Rupture, Thumb Osteoarthritis, Distal Radius Fracture
- Trial name
- NCT05095415
- Testing
- Occupational Therapy Pre-operative Consult, Typical Pre-Operative Education
- Sponsor
- Methodist University, North Carolina
Osteoarthritis Hand, Lumbago
Cardiovascular Risk in Digital Osteoarthritis
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and…
- Conditions
- Osteoarthritis Hand, Lumbago, Osteoporosis, Radiculopathy Lumbar
- Trial name
- RICARDI (NCT05923736)
- Testing
- Intima media thickness ultrasound, hand ultrasound, EndoPAT™ 2000 system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis
Evaluation of the Safety of LipiodolⓇ Embolization in Symptomatic Digital Osteoarthritis Refractory to Conventional Treatment
The goal of this clinical trial is to evaluate the safety of arterial embolization using Lipiodol® in patients with symptomatic hand osteoarthritis refractory to conventional treatment.
- Trial name
- EMBARDI (NCT06611007)
- Testing
- embolization therapy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Rheumatoid Arthritis, Osteoarthritis of Hands
Home Based Computer Gaming Hand Exercise Regimen for People With Arthritis Affecting the Hands
The purpose of the study is to determine whether a novel computer gaming hand exercise regimen would improve hand function, decrease pain/ stiffness and be feasible in people with Rheumatoid arthritis or Osteoarthritis affecting…
- Trial name
- NCT01635582
- Testing
- Conventional hand exercise program, Computer gaming hand exercise regimen
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Osteoarthritis
Effects of Neuromobilization, Tendon Gliding, and Robotic Glove-Assisted Exercises on Hand Osteoarthritis
The 2018 update of the EULAR recommendations highlighted that exercise reduces pain and improves functionality in patients with hand OA.
- Trial name
- NCT06901024
- Testing
- Tendon Gliding Exercise, Neuromobilization Exercise, Robotic Assitive Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Hasan Kalyoncu University
Early Stage Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC)for Osteoarthritis of the First CarpoMetacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion)in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01961570
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Articulinx
Thumb Osteoarthritis, Hand Osteoarthritis
Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment
Aim: We aim to determine and compare the efficiency of single dose intra-articular (IA) platelet rich plasma (PRP) and corticosteroid (CS) injections for the treatment of first carpometacarpal joint osteoarthritis (1.
- Conditions
- Thumb Osteoarthritis, Hand Osteoarthritis, Platelet Rich Plasma, Corticosteroid
- Trial name
- NCT06657300
- Testing
- PRP, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Erosive Hand Osteoarthritis
Methotrexate Treatment in Hand Osteoarthritis Refractory to Usual Treatments
Randomized study comparing the structural efficacy of methotrexate versus placebo in digital osteoarthritis
- Trial name
- ADEM2 (NCT07501507)
- Testing
- Methotrexate Injectable Solution
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Rheumatoid Arthritis, Axial Spondyloarthritis
Rheumatism and Dietetic: RHUMADIET Study (Food Practices and Beliefs)
Cross sectional study assessing food practices and beliefs in RA, AS and DA (digital arthritis)
- Conditions
- Rheumatoid Arthritis, Axial Spondyloarthritis, Hand Osteoarthritis
- Trial name
- RHUMADIET (NCT03770884)
- Where
- France
- Volunteers
- 448 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hand Osteoarthritis
Testing of a New Joint Protection Program
The goal of this study is to to examine the feasibility of a full-scale trial on Helping Hand, a new Joint Protection Program for Hand Osteoarthritis and to examine the acceptability of the new Joint Protection Program.
- Trial name
- "Helping Hand" (NCT06963164)
- Testing
- Helping Hand - Joint Protection Program
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's