Clinical trials: Hashimoto Thyroiditis
Selenium
Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis
To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.
- Trial name
- NCT04942769
- Testing
- Selenium
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Autoimmune Thyroiditis
Dysregulation of the Soluble α-Klotho-FGF23 Axis in Hashimoto's Thyroiditis: A Case-Control Study
Hashimoto's thyroiditis (HT) is the most common autoimmune thyroid disease and is increasingly recognized as a condition associated with chronic low-grade systemic inflammation beyond thyroid hormone dysfunction.
- Trial name
- klofgfhashi (NCT07453290)
- Testing
- Blood Sampling and Biomarker Measurement
- Volunteers
- 150 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Autoimmune Diseases, Chronic Lymphocytic Thyroiditis
Involvement of Viral Infections in the Pathogenesis of Chronic Lymphocytic Thyroiditis
Autoimmune diseases represent a heterogeneous group of pathologies whose etiopathogenic mechanisms are most often unknown. Autoimmune diseases are the leading cause of morbidity and mortality in young women and autoimmune thyroid…
- Trial name
- Etude thyrovir (NCT03114267)
- Testing
- Comparison of the prevalences of the parvovirus genome
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Thyroid Eye Disease, Graves Orbitopathy
Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled in the prior VGN-TED-301 through Week 24.
- Conditions
- Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases
- Trial name
- NCT06112340
- Testing
- linsitinib
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Sling Therapeutics, Inc.
Hashimoto Disease
Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
Oxidative stress leads to or accompanies with numerous disease. Oxidative balance in subclinical hypothyroid or euthyroid state in Hashimoto disease are not known.
- Trial name
- NCT01102205
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Vakif Gureba Training and Research Hospital
Autoimmune Thyroiditis, Hashimotos Thyroiditis
Selenium Treatment in Autoimmune Thyroiditis (AIT)
Selenium suppresses autoimmune destruction of thyrocytes and decreases titers of serum TPOAb in AIT patients. Older 4 clinical trials approved the efficacy of the daily dose of 200micg.
- Trial name
- NCT00271427
- Testing
- L-Selenomethionine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ege University
Hashimoto Thyroiditis, Graves Disease
DNA Methylation and Autoimmune Thyroid Diseases
Hashimoto Thyroiditis (HT) and Graves Disease (GD) are known to be caused by abnormal immune response against self cells and tissues.
- Trial name
- THYRODNA (NCT02491567)
- Where
- Greece
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Thyroiditis Autoimmune
Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT
Over the past 10 years, several clinical studies have suggested that selenium supplementation may influence the natural history of AIT.
- Trial name
- NCT02302768
- Testing
- Selenomethionine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Siena
Hypothyroidism, Hashimoto Disease
Gluten Free Diet in Hashimoto's Hypothyroidism
Hashimoto's thyroiditis is an autoimmune condition that reduces functioning of the thyroid gland and can lead to a substantial decline in quality of life for patients, with impacted patients often describing unremitting brain…
- Trial name
- NCT07060118
- Testing
- Gluten Free Diet in Hashimoto's Hypothyroidism
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Autoimmune Thyroid Disease, Type 2 Diabetes Mellitus (T2DM)
Fecal Microbiota Transplantation for Type 2 Diabetes Mellitus and Hashimoto's Thyroiditis
The goal of this clinical trial is to learn if fecal microbiota transplantation (FMT) can improve metabolic control and immune function in adults with both type 2 diabetes and Hashimoto's thyroiditis (an autoimmune thyroid…
- Conditions
- Autoimmune Thyroid Disease, Type 2 Diabetes Mellitus (T2DM), FMT
- Trial name
- NCT07733232
- Testing
- Fecal microbiota transplantation oral capsules
- Volunteers
- 38 people
- Sponsor
- Shen Xujun
Hashimoto's Thyroiditis
The Effect of Plaquenil on Serum Inflammatory Markers and Goiter in Euthyroid Young Women With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is a common form of autoimmune thyroid disease, which affects up to 2% of general population. The annual incidence of HT worldwide is estimated to be 0.8 - 3.5 cases per 1000 persons.
- Trial name
- NCT02126683
- Testing
- Hydroxychloroquine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Autoimmune Thyroiditis
Low Level Laser Therapy for Autoimmune Thyroiditis
INTRODUCTION: Chronic autoimmune thyroiditis (TCA) is the main cause of acquired hypothyroidism, which requires continuous treatment with levothyroxine (LT4).
- Trial name
- NCT02240563
- Testing
- Low-level laser therapy, Non laser ordinary red light
- Where
- 2 sites in Brazil
- Volunteers
- 43 people
- Sponsor
- University of Sao Paulo General Hospital
Hashimoto Disease
FGF-21 Levels and RMR in Children and Adolescents With Hashimoto's Thyroiditis (THYROMETABOL)
It is well documented that thyroid hormones (THs) are involved in energy and lipid metabolism, thermogenesis, and body weight control, acting on several tissues.
- Trial name
- THYROMETABOL (NCT02725879)
- Where
- Greece
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes, Hashimoto Disease
Telehealth Music Therapy for Adults With Endocrine Disorder and Depression
The goal of this clinical trial is to explore if a telehealth music therapy intervention helps with quality of life, depression symptoms, anxiety symptoms. It will also explore the participants' relationship to music.
- Conditions
- Type 1 Diabetes, Hashimoto Disease, Graves Disease, Addison Disease
- Trial name
- NCT07413874
- Testing
- Telehealth Resource Oriented Music Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Appalachian State University
Hashimoto Disease, Psoriasis
Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis
Hashimoto's disease (HT) and psoriasis (PsO) have a significant impact on patient's quality of everyday life, and early diagnosis is critical for the symptoms management and prognosis.
- Trial name
- METHAP (NCT04693936)
- Testing
- Nutraceutical Combination Plan
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Crete
Hashimoto Thyroiditis, Mediterranean Diet
The Impact of Change of Thyroid Antibodies on Hormone Level and Disease Burden in Patients With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is an autoimmune disease affecting the thyroid gland and is one of the most common causes of hypothyroidism. Eating habits may affect the risk of several inflammatory and immune diseases, such as HT.
- Trial name
- Anti-TPO/TG (NCT07048821)
- Testing
- Dietary modification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherihan AboElyazed Mohamed Khalil
Gut Microbiota
Gut Microbiota is Associated With Autoimmune Thyroid Disease
Autoimmune thyroid disease (AITD), which includes Hashimoto's thyroiditis (HT) and Grave's disease (GD), are the most common organ-specific autoimmune diseases and affect more women than men, with a female-to-male ratio from 5 to…
- Trial name
- NCT03390582
- Testing
- Methimazole Pill
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Thyroid Autoimmune Disease, Hashimoto's Thyroiditis
Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis
The purpose of this clinical trial is to evaluate whether a dietary intervention can improve clinical and immunological outcomes in women with autoimmune thyroid disease (AITD), including Hashimoto's thyroiditis and Graves'…
- Conditions
- Thyroid Autoimmune Disease, Hashimoto's Thyroiditis, Graves Disease
- Trial name
- TAILOR (NCT07879690)
- Testing
- Gluten-free, casein-free, low-glycemic-index diet
- Where
- Andorra
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Hashimoto Thyroiditis
rT3 and Inflammation in Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is characterized by an enlarged thyroid gland infiltrated with lymphocytes. The incidence of HT is estimated to be 0.3-1.5 cases per 1000 people, with a female/male predominance of 7-10:1.
- Trial name
- NCT07510750
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Polyoma Virus Infection, Thyroiditis, Autoimmune
Involvement of Polyomaviruses in the Pathogenesis of Autoimmune Thyroiditis and Goitrigenesis.
Autoimmune thyroiditis and goitres are frequent pathologies.
- Trial name
- IPoTAIG (NCT03103776)
- Testing
- Comparison of Positive PCR Frequencies for Polyomavirus in Blood, Urine and / or Thyroid Tissue vs Basedow / Hashimoto
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens