Clinical trials: Hay Fever
Pollen; Allergy, Asthma
Does Medicinal Mushroom Agaricus Blazei Protect Against Allergy and Asthma?
Asthma and allergy is increasing in Norway and Western countries. Treatment is still mostly symptomatic. Extracts of the immunomodulatory and edible mushroom Agaricus blazei, such as Andosan™, have been shown to protect against…
- Trial name
- NCT03198455
- Testing
- Agaricus blazei Murill-based mushroom extract, Andosan™
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Seasonal Allergic Rhinitis
Effect of Veramyst and Olopatadine 0.2% Opthalmic Solution on Allergy Symptoms
People who have hayfever or allergic rhinitis often complain about eye symptoms associated with their nasal symptoms. How people with hayfever develop eye symptoms is not clear.
- Trial name
- NCT01007253
- Testing
- PL nasal spray, fluticasone furoate (FF), PL eye drops
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Rhinitis, Allergic, Seasonal
Drug Utilization Study for Pirinase Hayfever Relief
The purpose is to obtain real-world information on how consumers are complying with the product labelling This study will coincide with the launch of Pirinase Hayfever Relief for Adults 0.05% Nasal Spray in the United Kingdom…
- Trial name
- NCT02856282
- Testing
- Pirinase Hayfever Relief for Adults 0.05% Nasal Spray
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Allergy Pollen
Microassay and Allergy Skin Prick Test Correlation Study
The purpose of this study is to evaluate the potential correlation of the results of allergen-specific skin prick tests (SPT) to that of allergen-specific microarray determination (microassay test).
- Trial name
- NCT03514303
- Testing
- Spiriplex Allergenex Microassay
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United Allergy Services
Pollen Allergy
Comparison of the Efficacy and the Safety of Different Schedules of Administration of Sub-lingual Immunotherapy
The dose and the mode of administration of sublingual therapy remain open questions to determine the efficacy and safety of this desensitization therapy, the main purpose of this study is to evaluate if different routes of…
- Trial name
- NCT01500642
- Testing
- Slit One, Slit One ragweed
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Hay Fever
Evaluation of High Speed Laser Doppler Imaging Technology
Skin prick tests (SPT) are commonly used in daily allergological practice to assess skin reactivity to allergens. Multiple factors can contribute to non-optimal results of conventional wheal and flare measurement (CWFM) of SPT…
- Trial name
- HSL-DI (NCT02619331)
- Testing
- Allergy test reading
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Seasonal Allergic Rhinitis, Healthy Subjects
A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions
Allergic Rhinitis is an inflammatory disease which causes an influx of inflammatory cells and cytokines into the nasal mucosa. These biomarkers can also be found in the nasal secretions.
- Trial name
- NCT00297843
- Testing
- allergen challenge (grass pollen), nasal lavage
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Hayfever
Lactobacillus Acidophilus L92 on Markers of Allergic Inflammation by Nasal Provocation With Grass Pollen
This is a placebo controlled double-blind single center study initiated and sponsored by CALPIS, Inc., Japan, and CALPIS U.S.A., Inc., Torrance, CA.
- Trial name
- NCT00554736
- Testing
- Lactobacillus acidophilus L-92
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis
This is a Prospective, Controlled, Double Blinded, Single Center, Randomized, 3 Arm, Parallel Assignment, Phase 1b/2a Study to assess the safety, tolerability, and preliminary efficacy of B244 delivered as an intranasal spray in…
- Conditions
- Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen, Healthy Volunteers
- Trial name
- NCT03290248
- Testing
- B244 suspension, Vehicle
- Where
- 2 sites in United States, Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- AOBiome LLC
Healthy, Allergic Rhinitis
Tolerability/Safety of Intranasal AZD8848 in Healthy Male Volunteers and Seasonal Allergic Rhinitis Male Patients Out of Season
Investigate safety/tolerability after a single dose intranasal administration of AZD8848 comparator placebo to healthy male volunteers and seasonal allergic rhinitis male patients out of season
- Trial name
- SAD (NCT00688779)
- Testing
- AZD8848
- Where
- Sweden
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Allergic Asthma, Thunderstorm Asthma
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study
Thunderstorm asthma is a recurring public health emergency in South-Eastern Australia which occurs in springtime. The major identified risk factors for thunderstorm asthma is hay fever and allergy to ryegrass pollen.
- Conditions
- Allergic Asthma, Thunderstorm Asthma, Seasonal Allergic Rhinitis, Grass Pollen Allergy
- Trial name
- CARISTA (NCT07055542)
- Testing
- Observational
- Where
- 6 sites in Australia
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Seasonal Allergic Rhinitis
A Single and Multiple Dose Study to Explore the Safety of JNJ-38224342 in Healthy Patients and Patients With Seasonal Allergies
A single and multiple dose study to assess the safety of JNJ 38224342 compared to placebo in healthy volunteers and in volunteers with seasonal allergies.
- Trial name
- NCT01054352
- Testing
- JNJ38224342
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Allergic Rhinitis, Seasonal Allergic Rhinitis
Assessment of Fluticasone Propionate on Ocular Allergy Symptoms
This study is designed to investigate the efficacy of fluticasone propionate (FP) on ocular symptoms associated with allergic rhinitis (AR).
- Trial name
- NCT01817790
- Testing
- Fluticasone propionate
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hay Fever
Safety and Efficacy Study of rEV131 in Allergic Rhinitis
The purpose of this study is to see whether rEV131 when given as a nasal spray in a single dose to each nostril is safe and can reduce the signs and symptoms of allergic rhinitis (hay fever) caused by an allergen challenge.
- Trial name
- NCT00247520
- Testing
- topical nasal rEV131
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolutec Group
COVID-19, Coronavirus Infections
Audio Data Collection for Identification and Classification of Coughing
An open access study that will define and collect digital measures of coughing in multiple populations and public spaces using various means of audio data collection.
- Conditions
- COVID-19, Coronavirus Infections, Hay Fever, Asthma
- Trial name
- NCT04326309
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.
Influenza Infection
Dose, Safety, Tolerability and Immunogenicity of an Influenza H1 Stabilized Stem Ferritin Vaccine in Healthy Adults
Background: The flu is a common viral infection that can be deadly for certain people. Vaccines against flu have been developed to teach the body to prevent or fight the infection.
- Trial name
- NCT03814720
- Testing
- VRC-FLUNPF099-00-VP (H1ssF_3928)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Seasonal Allergic Rhinitis
Single Center, Randomized, Double-Blind,Crossover Study Comparing Effects Of Single-Dose Fexofenadine HCl 180 mg, Cetirizine 10 mg, and Placebo on Cognitive Performance in Naval Flight Personnel
To compare the effects of fexofenadine HCl 180 mg, cetirizine 10 mg, and placebo on computerized scores derived from the Aeromedical Vigilance Task (AVT), a computerized objective measure of attention, accuracy and reaction time…
- Trial name
- NCT00637455
- Testing
- fexofenadine HCl
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sanofi
Asthma, Seasonal Allergic Rhinitis
Adolescent and Adult Subjects With Asthma and Seasonal Allergic Rhinitis Receiving Advair Diskus or Placebo
The four respiratory drugs being researched in this study have been approved by the US Food and Drug Administration (FDA) and are currently available by prescription at your drug store.
- Trial name
- NCT00385463
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Hayfever
Effects of Sublingual Immunotherapy on Grasspollen Allergy
The objective of the study is to document the objective immunological effects of SLIT on the nasal mucosa. Better understanding of these immunological pathways, in which this widely practised clinical therapy is likely to work…
- Trial name
- NCT00150514
- Testing
- Oralgen, Nasal biopsy, Nasal washing
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Rhinitis, Allergic, Nasal Allergy
Mometasone Furoate Nasal Spray in Italian Children
Objective Seasonal allergic rhinitis (SAR) is a common disease in childhood and characterized by type 2 inflammation, bothersome symptoms, and impaired quality of life (QoL).
- Conditions
- Rhinitis, Allergic, Nasal Allergy, Allergy Pollen, Nasal, Cytology
- Trial name
- NCT05301647
- Testing
- Nasal cytology, The validated Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ), Total symptom score (TSS)
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli