Clinical trials: HbA1c
Type 2 Diabetes Mellitus (T2DM)
A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM
To evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of ALN-KHK and to evaluate the safety, tolerability, efficacy, PK and PD of multiple doses of KHK.
- Trial name
- NCT05761301
- Testing
- ALN-KHK
- Where
- 15 sites in United States, Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Alnylam Pharmaceuticals
Diabetes
Comparison Study of Lay Person Finger Stick Versus Blood Draw
This is a study to evaluate the safety and effectiveness of Micro-Serum/Micro-Blood (finger Stick) Specimen Collection as compared to samples obtained by standard venipuncture (blood taken from the arm vein).
- Trial name
- NCT01913145
- Testing
- A1c, Self-collection, Blood sample
- Where
- 2 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Home Access Health Corporation
Type2 Diabetes, Self Efficacy
The Effect of IMB Model-Based Diabetes Education and Motivational Interviewing on Care Outcomes in Adults With T2DM
This study was conducted to examine the effects of IMB model-based diabetes education and Motivational Interviewing for adults with Type 2 diabetes on care outcomes This study was conducted to examine the effects of IMB…
- Conditions
- Type2 Diabetes, Self Efficacy, Self Management, HbA1c
- Trial name
- NCT05030844
- Testing
- IMB model based Diabetes Education and Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
PreDiabetes, Overweight and Obesity
Effect of a Probiotic on the Glycemic Profile and the Fecal Microbiota of Prediabetic Subjects (PREDIABETCARE)
According to the data from the Di@bet.es study, which is part of the National Diabetes Strategy, the prevalence of type 2 diabetes among Spanish population is 13.8%.
- Trial name
- PREDIABETCAR (NCT04863313)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Diabetic Retinopathy
Correlation Between HBA1c Level and Thickness of Both Macula and Choroid in Patients With Type 2 Diabetes Mellitus
Diabetic retinopathy (DR) is a frequent cause of visual impairment, and the leading cause of blindness in those of working age, but it develops silently along years, producing symptoms only in late stages.
- Trial name
- NCT05778370
- Testing
- Swept Source Optical Coherence Tomography(Topcon DRI Triton)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 1 Diabetes
Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin
Most of the studies concerning aerobic fitness in Type 1 diabetic patients noted a relationship between impaired aerobic fitness and high glycated haemoglobin (HbA1c) levels, reflecting poor long term glycaemic control.
- Trial name
- OXYDIAB (NCT02051504)
- Testing
- Incremental maximal exercise, Oral Glucose Tolerance Test, Muscle biopsy
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Type 2 Diabetes
Vitamin D Supplementation to Patients With Type 2 Diabetes
The purpose of the study is to evaluate if supplementation with vitamin D in a dose of 40.000 IU per week will result in improved metabolic control in patients with type 2 diabetes.
- Trial name
- NCT00400491
- Testing
- Cholecalciferol (vitamin D)
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Diabetes Mellitus, Type 2
The Proportion of Patients With Non-diagnosed Diabetes Type 2
The aims of the study are to determine the prevalence of diabetes in subgroups of the population with certain characteristics (age, gender, socioeconomic status, geographical area of residence), to estimate the proportion of…
- Trial name
- Sadkorna (NCT04230382)
- Testing
- Diagnosis of diabetes (OGTT)
- Where
- Slovenia
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Type 2 Diabetes, HbA1c
Daily Protein Pacing Effects on HbA1c in Type 2 Diabetics
This study will examine the effects of protein (whey) supplementation added to the normal diet of pre-diabetes or diagnosed type 2 diabetes mellitus (T2DM) men and women on plasma glycated hemoglobin (HbA1c) and total body fat…
- Conditions
- Type 2 Diabetes, HbA1c, Protein Intake
- Trial name
- NCT05355090
- Testing
- PP
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Type 1 Diabetes
Liraglutide in the Treatment of Type 1 Diabetes Mellitus
Hypothesis 1: Treatment with Liraglutide in patients with type 1 diabetes decreases fasting, postprandial and the overall mean glucose concentrations.
- Trial name
- NCT01722266
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Diabetes Mellitus, Type 2
Effect of FISH Intake on MEtabolic Health in a Diabetic South Asian popuLation (FISH MEAL)
The investigators will recruit non-diabetic volunteers (n=30) and diabetic volunteers controlled by diet and lifestyle (n=300). The non-diabetic volunteers will be in the non-diabetic group while the diabetic volunteers will be…
- Trial name
- FISHMEAL (NCT02840630)
- Testing
- Tinned mackerel fish
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Ischemic Foot Ulcer
Intensive Insulin Treatment and Ischemic Foot Ulcer
We aim to investigate the relationship between skin microvascular function and the first hospitalization for ischemic foot ulcer in patients with type 1 diabetes former randomized during 7.5 years to intensified conventional…
- Trial name
- NCT01957930
- Testing
- Intensified insulin treatment, Standard treatment
- Where
- 2 sites in Sweden
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Diabetes Mellitus, Type 2, Prediabetic State
PREDICT-DM: Community Pharmacy-Based Point-of-Care Testing for Undiagnosed T2DM
The goal of this observational study is to learn whether community pharmacy-based risk assessment and point-of-care HbA1c testing can help detect undiagnosed type 2 diabetes and prediabetes among adults in Irbid Governorate…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Prediabetes / Type 2 Diabetes, T2DM
- Trial name
- PREDICT-DM (NCT07795918)
- Where
- Jordan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Vitamin D Deficiency
Effect of Vitamin D3 and Omega-3FA on Leptin and HbA1C With Vitamin D Deficiency
The Combined effect of Vitamin D3 and Omega-3 supplements on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.
- Trial name
- NCT03735303
- Testing
- VD3 group, omega 3 FA group, VD3 and omega- 3FA group
- Where
- Jordan
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Pre-diabetes
Effect of a Plant-based Hydrolysates Daily Consumption on the HbA1c of Pre-diabetic Subjects
This study evaluates the effect in HbA1c levels of a once daily administration of plant-based hydrolysates in pre-diabetic, but otherwise healthy volunteers.
- Trial name
- NCT03851666
- Testing
- 12 weeks daily administration Cereal 1, 12 weeks daily administration Cereal 2
- Where
- 2 sites in Latvia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Onorach Clinical Ltd
Diabetes Mellitus With Periodontal Disease
The Effect of Topical Doxycycline Gel on HbA1c in Patients With Type 2 Diabetes Mellitus(DM) ®
Aim: The purpose of this study is to investigate the effect of nonsurgical periodontal therapy plus subgingivally doxycycline gel 3% on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have periodontitis.
- Trial name
- NCT02735837
- Testing
- Doxycycline Group
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amirhossein Farahmand
Polycystic Ovary Syndrome, Insulin Resistance
Acupuncture or Metformin for Insulin Resistance in Women With PCOS
The hypothesis is that acupuncture is equally effective as metformin (both treatments combined with lifestyle management) in improving whole body glucose homeostasis in insulin resistant women with polycystic ovary syndrome…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Hyperandrogenism
- Trial name
- PIAII (NCT02647827)
- Testing
- Lifestyle management, Acupuncture, Metformin
- Where
- 2 sites in China, Sweden
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pre-diabetes, Metabolic Syndrome
Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers
The primary goal is to to characterize the effects of consuming 1 avocado fruit 7 days / week (5-7 days is acceptable) compared to a no avocado relatively low fat, carbohydrate control treatment over a 12 week period on insulin…
- Trial name
- AV2 (NCT02695433)
- Testing
- Active, Control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Type 2 Diabetes
HBA1c and Diagnosis of Type 2 Diabetes
Following the 6th Tromso study subjects with HbA1c > 5.7 plus a subsample of subjects with lower hba1c values will be invited to an oral glucose tolerance test to see the predictive value of HBA1c in the diagnosis of type 2…
- Trial name
- NCT01184768
- Where
- Norway
- Volunteers
- 3,509 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Glucose Response
Glycemic Effects of Meals - Repeatability Trial With Continuous Glucose Monitoring
Almost half of adults in the United States have either diabetes mellitus (DM) or prediabetes (preDM), but many are undiagnosed and unaware of their condition.
- Trial name
- GEM-RT CGM (NCT07293143)
- Testing
- Six meal challenges
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston University