Clinical trials: Head and Neck Lymphedema
Head and Neck Cancer
Effects of a Home-Based Exercise Program During Radiotherapy
The purpose of this study is to examine the effects of exercise on individuals with head and neck cancer who are receiving postoperative radiotherapy. The study is based on three primary hypotheses: 1.
- Trial name
- NCT07376213
- Testing
- Home-based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Burak Ertürk
Head and Neck Cancer, Lymphedema of Face
Two Different Physiotherapy Programs in Lymphedema Following Head and Neck Cancer Treatment
The aim of this study was to determine the effects of complex decongestive physiotherapy (CDP) and home programs on internal/external lymphedema, staging, fibrosis, and three-dimensional (3D) surface scanning and volume…
- Conditions
- Head and Neck Cancer, Lymphedema of Face, Fibrosis; Skin
- Trial name
- NCT04286698
- Testing
- Complex decongestive physiotherapy, Home program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Izmir Bakircay University
Breast Cancer, Head and Neck Cancer
Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema
RATIONALE: Acupuncture and moxibustion may improve well-being and quality of life in patients with lymphedema caused by breast cancer or head, neck, and throat cancer.
- Conditions
- Breast Cancer, Head and Neck Cancer, Lymphedema
- Trial name
- AMWELL-SL (NCT00828516)
- Testing
- Acupuncture and moxibustion
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- East and North Hertfordshire NHS Trust
Head and Neck Cancer
Preventing Lymphedema in Patients Undergoing Surgical Treatment for Head and Neck Cancer Through Vein Reconstruction
The goal of this clinical trial is to learn if facial vein reconstruction after neck dissection works to reduce rates of lymphedema in adults getting surgical treatment for head and neck cancer.
- Trial name
- NCT07694726
- Testing
- Facial Vein Reconstruction
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Pittsburgh
Head and Neck Cancer, Lymphedema
Comparing Two Ways to Manage Head and Neck Lymphedema
This randomized clinical trial aims to compare clinic-based CDT and home-based (a hybrid model) CDT on changes in the severity of lymphedema, symptom burden, functional status, and healthcare utilization in HNC survivors with…
- Trial name
- NCT05182229
- Testing
- Home-based (a hybrid model) CDT, Clinic-based CDT
- Where
- 6 sites in United States
- Volunteers
- 240 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lymphedema, Lymphedema of Face
Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani
The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during open lymphatic reconstruction in the head and neck.
- Conditions
- Lymphedema, Lymphedema of Face, Internal Lymphedema, External Lymphedema
- Trial name
- CLEAR (NCT07311876)
- Testing
- Symani Surgical System
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Cancer of Head and Neck
Lymphoedema Among Persons With Head- and Neck Cancer
Lymphedema in the head and neck area is common after treatment for head and neck cancer. The aim of the research project is: to assess the prevalence of lymphedema in patients with head and neck cancer (HNC) by measuring the…
- Trial name
- NCT05316974
- Testing
- Prevalence of lymphoedema
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University
Lymphedema of Face, Head and Neck Cancer
Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship
The goal of this clinical trial is to learn if treating the lymphatics in head and neck cancer survivors before clinical diagnosis of lymphedema will prevent its development or progression.
- Trial name
- NCT05937269
- Testing
- Near-infrared fluorescence lymphatic imaging, advanced pneumatic compression therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Head and Neck Cancer, Lymphedema
Developing a Checklist of Lymphedema Symptoms in Patients With Head and Neck Cancer
RATIONALE: Developing a symptom checklist for late-effect lymphedema may help doctors learn more about lymphedema in patients with head and neck cancer and plan the best treatment.
- Trial name
- NCT00840814
- Where
- 3 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Head and Neck Cancer, Lymphedema of the Head and Neck
Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema
The U.S. Food and Drug Administration approved photobiomodulation therapy (PBMT) as a treatment for breast cancer-related arm lymphedema (BCRL) in 2006. The investigators conducted two pilot clinical trials.
- Trial name
- NCT06837480
- Testing
- LTU-904 Portable Laser Therapy Unit (active laser device)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma
A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation
This clinical trial tests whether adding the use of a pneumatic compression system with manual lymphatic drainage versus manual lymphatic drainage alone in treating patients with lymphedema after chemoradiation for stage II-IV…
- Conditions
- Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage IV HPV-Mediated (p16-pos)Oropharyngeal Carcinoma, Head and Neck Carcinoma
- Trial name
- NCT05512767
- Testing
- Best Practice, Consensus Auditory-Perceptual Evaluation of Voice, Diagnostic Imaging
- Sponsor
- Mayo Clinic
Lymphedema, Secondary
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema
Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.
- Trial name
- NCT04457375
- Testing
- TDC
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Radiation Lymphedema, Radiation Fibrosis
Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients
Radiation fibrosis syndrome (RFS) is a general side effect of radiation therapy (RT) which can adversely impact patients chronically over years typically triggered by an acute inflammatory state that evolves into chronic…
- Conditions
- Radiation Lymphedema, Radiation Fibrosis, Head and Neck Cancer
- Trial name
- PBM-LEF (NCT06708754)
- Testing
- Photobiomodulation (PBM) Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Head and Neck Cancer, Lymphedema
Low-Level Laser in Treatment of Head and Neck Lymphedema: A Pilot Study
The purpose of this pilot clinical trial is to evaluate the feasibility of the use of low-level laser for head and neck cancer survivors with lymphedema.
- Conditions
- Head and Neck Cancer, Lymphedema, Fibrosis
- Trial name
- NCT03738332
- Testing
- Low-Level Laser
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Head and Neck Neoplasms, Head and Neck Cancer
A Pilot Study to Evaluate the Feasibility and Potential Effectiveness of the Flexitouch System Head and Neck Treatment
The study will evaluate the feasibility and potential effectiveness of the Flexitouch head and neck treatment plus standard home care compared to standard home care regimen alone.
- Conditions
- Head and Neck Neoplasms, Head and Neck Cancer, Head and Neck Lymphedema
- Trial name
- NCT03332160
- Testing
- Flexitouch head and neck lymphedema treatment system, Standard home lymphedema care
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Tactile Medical
Head and Neck Squamous Cell Carcinoma, Lymphedema, Secondary
Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery
Head and neck squamous cell carcinoma is one of the most common malignant tumors. At present, the standard treatment of head and neck squamous cell carcinoma recommended by the National Comprehensive Cancer Network(NCCN)…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Lymphedema, Secondary, Neck Lymph Dissection, Vascularized Lymph Node Transplantation
- Trial name
- NCT06815705
- Testing
- Vascularized lymphatic transplantation
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Head and Neck Cancer, Lymphedema
Low-Level Laser in Head and Neck Chronic Lymphedema
The purpose of this study is to evaluate the effect of low-level laser treatment (LLLT) on the severity of lymphedema, symptom burden, functional status, and quality of life in HNC survivors.
- Conditions
- Head and Neck Cancer, Lymphedema, Fibrosis
- Trial name
- NCT04482855
- Testing
- Low-level laser
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Oral Cavity Carcinoma, Oropharyngeal Cancer
Physiotherapy Treatment for Patients Suffering From Head and Neck Cancer
The purpose of this study is to investigate whether the extent of late sequelae symptoms(reduced mouth opening, lymphoedema, decreased range of motion in the neck and shoulder region, speech and swallow disorders and reduced…
- Conditions
- Oral Cavity Carcinoma, Oropharyngeal Cancer, Adverse Effect of Radiation Therapy, Trismus
- Trial name
- HOHF (NCT00780312)
- Testing
- physiotherapy
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lymphedema, Oropharyngeal Cancer
Complete Decongestive Therapy (CDT) for Treatment of Head and Neck Lymphedema
Objectives: Specific Aim 1: Estimate the prevalence of head and neck lymphedema in patients who have been treated with surgery and/or radiation therapy (± chemotherapy) for oral cavity and oropharyngeal cancer.
- Conditions
- Lymphedema, Oropharyngeal Cancer, Head and Neck Cancer, Oral Cancer
- Trial name
- NCT00951470
- Testing
- Follow -Up Visits, Full CDT, Modified CDT Program
- Sponsor
- M.D. Anderson Cancer Center
Head and Neck Cancer
Lymphedema Treatment in Head and Neck Cancer Patients
The purpose of this research is to evaluate the result of treatment for neck lymphedema on throat pressure in patients who have received radiation therapy for head and neck cancer.
- Trial name
- NCT04276454
- Testing
- Flexitouch Plus system
- Where
- United States
- Sponsor
- Endeavor Health