Clinical trials: Headache Disorder
Migraine, Trigger Induced Migraine
Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US
Single-center, open label, prospective study conducted at Medstar Georgetown Headache Center. Men and woman ≥ 18 years old that are diagnosed with migraine with or without aura for at least 1 year, who report a reliable migraine…
- Trial name
- RIM (NCT07301008)
- Testing
- Rimegepant 75 MG
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Migraine
Ginger Capsules for the Acute Treatment of Migraine Attacks
The main objective of the study was to evaluate ginger efficacy as an adjuvant to ketoprofen for the treatment of headache and other symptoms related with migraine attacks.
- Trial name
- NCT02568644
- Testing
- Extract of ginger, Cellulose, Intravenous ketoprofen
- Volunteers
- 60 people
- Sponsor
- Federal University of Minas Gerais
Secondary Headache Disorders, Medication-overuse Headache
Medication-overuse Headache: The Effect of a Patient Educational Programme as an add-on to Standard Treatment
The aim of this study is to evaluate the influence of personality profiles in patients with MOH and to evaluate the effect of a custom-made educational programme as an add-on to standard treatment as compared to standard…
- Trial name
- NCT02768233
- Testing
- Educational programme
- Volunteers
- 98 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Migraine, Headache Disorders
MIGRAFIT: Evaluating a Group Therapy Program Combining Physical Activity, Progressive Muscle Relaxation and Psychoeducation for Adolescents With Migraine
Background: Migraine is a headache disorder highly prevalent in children and adolescents. It significantly affects academic performance and quality of life.
- Conditions
- Migraine, Headache Disorders, Pediatric Migraine
- Trial name
- NCT07419607
- Testing
- Weekly group training
- Where
- Austria
- Volunteers
- 6 people
- Sponsor
- Medical University Innsbruck
Migraine, Temporomandibular Joint Disorders
Changes and Associations Between Cervical Range of Motion, Pain, TMJ Range of Motion and Quality of Life in Migraineurs Applying Physical Therapy
The purpose of this study is to assess the effects of physiotherapy program and review the associations between neck movements, pain, temporomandibular joint (TMJ) movements and quality of life in individuals with migraine.
- Conditions
- Migraine, Temporomandibular Joint Disorders, Myofascial Trigger Point Pain
- Trial name
- NCT04729699
- Testing
- Aerobic exercise and exercise for TMJ, Aerobic exercise at home
- Where
- Lithuania
- Volunteers
- 19 people
- Sponsor
- Lithuanian University of Health Sciences
Mental Disorders
Comparison of Drugs on Headache Treatment After ECT Treatment
Electroconvulsive treatment (ECT) is still actual for treatment of psychiatric symptoms. Headache is a very common symptom after this application.
- Trial name
- NCT03830398
- Testing
- Paracetamol, Deksketoprofen trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Mustafa Kemal University
Cluster Headache
Repeated GON Injections in CCH
Background: The effect of repeated GON-injections has never been studied in a double-blind randomized trial as a prophylactic therapy in a well-documented group of chronic patients.
- Trial name
- REGON (NCT05324748)
- Testing
- Methylprednisolone, Saline solution
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Migraine Headache
Ibudilast in the Treatment of Patients With Chronic Migraine.
This will be a double-blind, randomised, placebo-controlled, two period cross over study of ibudilast in the treatment of chronic migraine. For participants resident in Adelaide, South Australia (i.e.
- Trial name
- IBU-003 (NCT01389193)
- Testing
- Ibudilast
- Where
- Australia
- Volunteers
- 33 people
- Sponsor
- Parisa Gazerani
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Cervicogenic Headache
Therapeutic Effectiveness of Dry Needling and Acupressure Therapy Among Patients With Cervicogenic Headache
A randomized controlled trial (RCT) with a pre-test and post-test design will be conducted to compare the therapeutic effectiveness of Dry Needling (DN), Acupressure Therapy (AT), and their combination (DN + AT) against a control…
- Trial name
- headache (NCT07192497)
- Testing
- DRY NEEDLING, Acupressure, Dry needling and Acupressure therapy
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- National Health Care Center (NHC) The Doctors Plaza Physical Therapy
Chronic Migraine, Headache, Overuse Headache Medication
Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg Vs Placebo As Adjuvant Treatment in Chronic Migraine -
To evaluate the effect of the cannabidiol (CBD) + cannabigerol (CBG) + tetrahydrocannabinol (THC) up to 133/66/4mg daily versus placebo as adjuvant treatment in chronic migraine (CM) patients under preventive treatment at a…
- Trial name
- CAMTREA (NCT04989413)
- Testing
- Cannabidiol + Cannabigerol + Tetrahydrocannabinol 133/66/4mg
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Hospital Israelita Albert Einstein
Cervicogenic Headache
Dry Needling Versus Instrumented Assisted Soft Tissue Mobilization In the Patient With Cervicogenic Treatment Headache
the aim of this study is to investigate the efficacy of Dry Needling Versus Instrumented Assisted Soft Tissue Mobilization In the Patient With Cervicogenic Treatment Headache
- Trial name
- DN (NCT05446649)
- Testing
- dry needling, instrumented assisted soft tissue mobilization, conventional therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Postdural Puncture Headache, Epidural Analgesia, Obstetric
A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device
The purpose of the study is to learn more about a new device, the EpiZact Epidural Device, that may be helpful for reducing the likelihood of wet tap when a labor epidural is placed.
- Trial name
- NCT06729255
- Testing
- EpiZact-assisted epidural placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Post-Dural Puncture Headache
Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section
comparison between oral sumatriptan and Nebulized Dexmedetomidine in Post Dural Puncture Headache in Cesarean Section
- Trial name
- NCT06514040
- Testing
- Precedex, Sumatriptan 25 mg
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
COVID-19
COVID-19 Pandemic and Migraine Disorder, Tension Headache and Epilepsy
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already rapidly spread around the world as a pandemic after its first report in Wuhan, China on December 12th 2019 …
- Trial name
- NCT05205590
- Testing
- Non
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University
Dysmenorrhea, Headache, Migraine
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
- Conditions
- Dysmenorrhea, Headache, Migraine, Fatigue, Nausea
- Trial name
- NCT04091789
- Testing
- Pure Femme Tablets
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Pure Green
Tension-Type Headache
Evidence-Based Osteopathy for Tension-Type Headache (EBOTTH)
Tension-type headache (TTH) is a very common primary headache disorder, with important costs for both patients and society. Often these patients are not willing to take prophylactic medications and resort to complementary…
- Trial name
- EBOTTH (NCT02592850)
- Testing
- osteopathic manipulative treatment
- Sponsor
- University of Milano Bicocca
Refractory Chronic Cluster Headache
Refractory Chronic Cluster Headache: Exploring the Potential of Repetitive Transcranial Magnetic Stimulation
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC.
- Trial name
- NCT06917144
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hospital Universitario La Paz
Tension-Type Headache
Diacutaneous Fibrolysis, Effects on Tension Type Headache
Tension Type Headache (TTH) is a frecuent type of headache disorder (about 1 person in 5 worldwide). Individuals with TTH typically present pericraneal tenderness and an increased cervical muscle tone.
- Trial name
- NCT03056131
- Testing
- Diacutaneous Fibrolysis
- Volunteers
- 82 people
- Sponsor
- Sara Cabanillas Barea
Breakthrough Bleeding, Breakthrough Spotting
Management of Breakthrough Bleeding During Extended Therapy Use With NuvaRing®
The purpose of this research study is to evaluate the best way to manage breakthrough spotting and bleeding during an extended use regimen of NuvaRing®.
- Trial name
- NCT00475553
- Testing
- remove ring if bleeding or spotting occurs more than 5 days, If bleeding does not remove ring
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
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