Clinical trials: Headache Disorder
Migraine
Evaluation of the Performance of the Doraldo-Castelletti Scale in Supporting the Neurologist's Decision to Refer Migraine Patients to Physiotherapy
Migraine is the leading cause of disability worldwide among people aged 15 to 49. Although therapies targeting the CGRP pathway have improved the management of the condition, there are large groups of patients who do not respond…
- Trial name
- MIGSKA (NCT07626307)
- Testing
- Doraldo-Castelletti scale
- Where
- Italy
- Volunteers
- 439 people
- Sponsor
- Istituto Auxologico Italiano
COVID-19
The Effects of Long-Term Mask Use in the Pandemic Period
Various restrictions have been made all over the world due to coronavirus pandemics. In addition to situations such as social isolation and hygiene, the use of masks is among these rules.
- Trial name
- NCT05358665
- Testing
- mask use
- Where
- Turkey (Türkiye)
- Volunteers
- 909 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Chronic Migraine or Episodic Migraine
Study to Evaluate the Efficacy and Safety of AMG 301 in Migraine Prevention
To evaluate the effect of AMG 301 compared to placebo on the change from the baseline period in monthly migraine days in subjects with migraine.
- Trial name
- NCT03238781
- Testing
- AMG 301
- Where
- 49 sites in United States, Austria and 6 more
- Volunteers
- 343 people
- Sponsor
- Amgen
Migraine, Cannabis
Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment
This pilot crossover study will evaluate 3 different potencies of inhaled cannabis (2.5%, 5%, and 10%) and inhaled placebo cannabis for the acute treatment of migraine.
- Conditions
- Migraine, Cannabis, THC
- Trial name
- NCT05427630
- Testing
- THC ~2.5%, THC ~5%, THC ~10%
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Stress Related Disorder, Musculoskeletal Pain
Immediate Effect of Energy Alignment and Mantra on Stress Related Pain in Adolescents
Psychiatrists have expressed concern at the emergence of education as a serious source of stress for school-going children - causing high incidence of deaths by suicide.
- Conditions
- Stress Related Disorder, Musculoskeletal Pain, Headache
- Trial name
- NCT03308630
- Testing
- Yoga based Energy Alignment and Mantra
- Where
- India
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Migraine
A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine.
This proof of concept clinical study will investigate the efficacy of active lens with frame in alleviating the symptoms of migraine which are caused by photosensitivity.
- Trial name
- NCT04904328
- Testing
- Lumishade® Active Lens
- Volunteers
- 77 people
- Sponsor
- Mitsui Chemicals, Inc.
Migraine
Normobaric Oxygen (NBO) Therapy in Acute Migraine
This is a pilot study investigating the therapeutic potential of breathing 100% oxygen in acute migraine headache.
- Trial name
- NCT01542307
- Testing
- Oxygen, Room air
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Tension-Type Headache
Effectiveness of Vagus Nerve Stimulation in Individuals With Tension-Type Headache
It is planned to examine the effect of Vagus Nerve Stimulation on headache symptoms in individuals with tension-type headache.
- Trial name
- NCT06604637
- Testing
- Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bitlis Eren University
Migraine Disorders, Headache
Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Chronic Migraine in Korea
This study is a Post-Marketing Surveillance study in Korea to evaluate the safety and efficacy of botulinum toxin Type A to treat Chronic Migraine in clinical practice.
- Trial name
- NCT01976611
- Testing
- botulinum toxin Type A
- Where
- South Korea
- Volunteers
- 402 people
- Sponsor
- Allergan
Chronic Migraine
Use of the Tx360 Nasal Applicator in the Treatment of Chronic Migraine
Migraine imposes a substantial burden on patients in terms of diminished daily functioning, quality of life, and financial loss.
- Trial name
- Tx360 (NCT01709708)
- Testing
- Marcaine, Saline
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Tian Medical Inc.
Migraine, Transcranial Magnetic Stimulation Repetitive
Individualized Location-based rTMS for Migraine Treatment: A Multicenter Clinical Study
For migraine patients experiencing at least four attack days per month and undergoing transcranial magnetic stimulation (TMS) treatment, a randomized, double-blind controlled trial is conducted, dividing participants into a…
- Trial name
- individua rTMS (NCT07086274)
- Testing
- Individualized location-based Repetitive Transcranial Magnetic Stimulation, Traditional location-based Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 152 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Cervicogenic Headache
Comparative Effects Of Eye-Cervical Re-Education Exercises And Pressure Biofeedback Training Of Deep Cervical Flexors In Cervicogenic Headache
Cervicogenic headache (CGH) is a secondary headache that originates from dysfunction in the upper cervical spine, particularly the atlanto-occipital and C1-C3 segments, and is perceived in one or more regions of the head and/or…
- Trial name
- NCT07526025
- Testing
- Eye cervical re-education exercises, Pressure biofeedback training group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Migraine
Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults
This Phase 2 trial will evaluate the efficacy and safety of ABP-450 for migraine prevention in adults who suffer from six or more migraine days per month.
- Trial name
- NCT04845178
- Testing
- ABP-450
- Where
- 62 sites in United States, Australia and 1 more
- Volunteers
- 797 people
- Sponsor
- AEON Biopharma, Inc.
Migraine
High School Start Time and Teen Migraine Frequency
Migraine is common in adolescents and can cause missed school and disability. The American Academy of Pediatrics (AAP) recommends that high schools start no earlier than 8:30 AM in order to accommodate the physiologic needs of…
- Trial name
- NCT03766412
- Testing
- High School start time
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of California, San Francisco
Aneurysmal Subarachnoid Hemorrhage (aSAH), Headache Disorders
Efficacy of Scalp Block in Managing Post Subarachnoid Hemorrhage Headache in Critically Ill Patients. A Single Centre Randomized Controlled Trial
Subarachnoid hemorrhage (SAH) is a devastating neurological disorder associated with significant mortality and morbidity rates, arising not just from the hemorrhage itself but also because of the catastrophic multisystem sequelae…
- Trial name
- SAH-BLOCK (NCT07307508)
- Testing
- Levobupivacaine Scalp block, Conventional analgesic therapy
- Where
- Qatar
- Volunteers
- 22 people
- Sponsor
- Hamad Medical Corporation
Migraine
Migraine Prophylaxis With Clopidogrel Trial
The underlying mechanisms of association between the right-to-left shunts (RLS) and migraine may concern with platelet aggregation and paradoxical embolization.
- Trial name
- NCT02938182
- Testing
- clopidogrel
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Tension-Type Headache
Evidence-Based Osteopathy for Tension-Type Headache (EBOTTH)
Tension-type headache (TTH) is a very common primary headache disorder, with important costs for both patients and society. Often these patients are not willing to take prophylactic medications and resort to complementary…
- Trial name
- EBOTTH (NCT02592850)
- Testing
- osteopathic manipulative treatment
- Sponsor
- University of Milano Bicocca
Migraine Disorders
Topiramate and Cerebrovascular Response in Migraineurs
The purpose of this study is to evaluate the effect of topiramate on cerebrovascular reactivity and mean flow velocity to photic stimulation in migraineurs.
- Trial name
- NCT02424318
- Testing
- Topiramate
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- SMG-SNU Boramae Medical Center
Cervicogenic Headache
Deep Neck Flexors Training Versus Muscle Energy Technique on Cervicogenic Headache
Aim of this study is to compare the effects of deep neck flexors stretching versus muscles energy technique on pain, cervical range of motion, sleep disturbance and cervical spine posture in patients with Cervicogenic headache…
- Trial name
- NCT05754931
- Testing
- Deep neck flexors training + Conventional therapy, Muscles energy techniques + conventional therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Bruxism
TMJ-1001 Bruxism Run-In/Pivotal Trial
The study is an open-label, prospective, multi-center, randomized, two treatment parallel, comparison study of the TMJ NextGeneration(TM) and custom-fit occlusal splint in the reduction of nocturnal bruxism episodes and monthly…
- Trial name
- NCT02269553
- Testing
- TMJ(TM) NextGeneration, Standard Hard TMJD Splint
- Sponsor
- TMJ Health
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