Clinical trials: Headache Disorders
Intracranial Aneurysm, Subarachnoid Hemorrhage
CorPath® GRX Neuro Study
The primary objective of this study is to evaluate the effectiveness and safety of robotic-assisted endovascular embolization procedures compared to objective performance criteria for traditional, manual operation based on the…
- Conditions
- Intracranial Aneurysm, Subarachnoid Hemorrhage, Headache
- Trial name
- NCT04236856
- Testing
- Robotic Endovascular Procedure
- Where
- 10 sites in Australia, Austria and 4 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Reversible Cerebral Vasoconstriction Syndrome
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome
This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised…
- Trial name
- TARDIS (NCT04179383)
- Testing
- Constitution of a biobank
- Where
- France
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Fibromyalgia (FM), Chronic Migraine Headache
Relieving Chronic Pain: Psychosomatic Mechanisms and Psychological Interventions in Fibromyalgia and Chronic Headache
Pain is one of the most important manifestations of the disease state and significantly affects people\'s quality of life. According to the International Association for the Study of Pain (IASP), pain is not only a sensory…
- Trial name
- FIBROMIG (NCT06652724)
- Testing
- Dynamic interpersonal therapy (DIT), technique of expressive writing (TSE), Treatment as Usual (TAU)
- Where
- 2 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Chronic Migraine, Fibromyalgia
Study of Low-dose Naltrexone in Chronic Migraine With Fibromyalgia
This research aims to look at the effect of low-dose naltrexone on the severity and frequency of attacks in people with chronic migraine with or without new daily persistent headache and fibromyalgia.
- Conditions
- Chronic Migraine, Fibromyalgia, New Daily Persistent Headache
- Trial name
- NCT05536050
- Testing
- Migraine diary and Questionnaires
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Migraine, Obesity
Diet and Migraine Study
The purpose of this study is to look at two different diets (a low carbohydrate diet and a low fat diet) for migraine prevention in overweight or obese persons with migraine.
- Trial name
- NCT01859052
- Testing
- Low carbohydrate diet, Low calorie low fat diet, AHA diet recommendations
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Primary Headache Disorder
Primary Headache and Psychological Factors, Mental Functioning and Attachment Modalities.
The World Health Organization (WHO) ranks headache among the top 20 causes of disability in the world. Primary headaches (with no known organic cause) account for 90% of these conditions.
- Trial name
- CEPRIVA (NCT03499392)
- Testing
- psychological tests
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Migraine, Epilepsy
High-field MR Imaging in Migraine, Visual Snow and Epilepsy
In this project, the aim is to recruit patients with drug resistant epilepsy and those suffering from migraine. Interestingly, patients suffering from epilepsy are also more often reporting to suffer from migraine.
- Conditions
- Migraine, Epilepsy, Visual Snow Syndrome
- Trial name
- NCT05524493
- Testing
- Structural MRI, Quantitative MRI, Diffusion MRI
- Where
- 2 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Post-Dural Puncture Headache
Long Term Outcomes Following a Post Dural Puncture Headache
Epidural analgesia is considered a gold standard method for treatment of labor pain. One of the major risks with epidural analgesia is an accidental dural puncture, which leads to a post dural puncture headache.
- Trial name
- NCT03550586
- Testing
- Questionaires
- Where
- 2 sites in Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Headache Disorders
Assessing the Diagnostic Accuracy of an On-line Questionnaire for Diagnosis of Primary Headache Disorders
Purpose of the study is to assess the diagnostic accuracy of an on- line questionnaire in comparison to a semi-structured interview administered by a trained interviewer.
- Trial name
- NCT03304886
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Stanford University
Headache, Migraine
The Effect of Adenosine on Cranial Hemodynamic, Headache and Migraine Induction Properties.
Adenosine is a nucleoside that plays a role in both vascular and nociceptive systems, and it has been proposed that adenosine may cause headache in particularly sensitive subjects.
- Trial name
- NCT04577443
- Testing
- Adenosine, Saline
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine Headache
A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches
To study the effect of Rozerem, a high affinity MT1 and MT2, low affinity 5-HT2B receptor agonist used for insomnia, as a migraine prophylactic agent.
- Trial name
- NCT00391755
- Testing
- ramelteon
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Charlottesville Neuroscience
Migraine, Migraine Headache
Migraine Attack Pain Phase Prediction Study
The study of the ability to predict pain in a migraine attack, through premonitory symptoms and through an ambulatory monitoring device through real-time recording of hemodynamic variables, is one of the strategic lines of…
- Conditions
- Migraine, Migraine Headache, Migraine Disorders, Migraine Without Aura
- Trial name
- PREDI-CRISIS (NCT06459635)
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Migraine
The Effect of Sumatriptan and Placebo on Cilostazol Induced Headache
To develop a pragmatic migraine model the investigators will induce headache in healthy volunteers and in patients with migraine without aura with a phosphodiesterase inhibitor (cilostazol).
- Trial name
- NCT02486276
- Testing
- Cilostazol, Sumatriptan
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Copy Number Variation in CHRNA7 Gene in Migraine and Gene Expression
Migraine is a common and possible hereditary disease. Copy number variation (CNV) is a phenomenon in which parts of the genome are repeated and the number of repeats in the genome varies between individuals in the human…
- Trial name
- NCT04912752
- Testing
- Migraine CNV
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Post Dural Puncture Headache
"Isometric Lower Limbs Exercises Affect on Cardiac Parameters and Headache in Patient After Spinal Anesthesia"
the Objectives of this clinical trial is : 1. Examine the effect of lower limbs isometric muscle exercises on cardiac parameters in patients after spinal anesthesia. 2.
- Trial name
- LILE-SPA (NCT07547150)
- Testing
- Lower Limb Isometric Exercise
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karbala University
Migraine
Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin
The involvement of calcitonin gene-related peptide (CGRP) in the cinnamaldehyde-induced dermal blood flow increase and in the mechanism of action of triptans will be investigated.
- Trial name
- NCT05654298
- Testing
- Sumatriptan, Ubrogepant
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postdural Puncture Headache
Study Evaluating Sphenopalatine Ganglion Block (SPGB) for Treatment of Postdural Puncture Headache (PDPH)
Postdural puncture headaches (PDPH) are a consequence of spinal and epidural anesthesia in approximately 1% of cases when performed in obstetric patients.
- Trial name
- PDPH (NCT02365909)
- Testing
- 0.5% bupivacaine, normal saline
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Headache Disorders, Primary, Prevalence
Headache in Undergraduate Students and Biopsychosocial Status
The primary aim of this study was to determine the prevalence of headache in undergraduate students. The frequency, duration, localizations and symptoms of headache will be determined with the information obtained as a result of…
- Conditions
- Headache Disorders, Primary, Prevalence, Migraine, Student
- Trial name
- NCT05843760
- Testing
- personal information form, headache-specific questionnaires, Questionnaires for assessing biopsychosocial status
- Where
- Turkey (Türkiye)
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- şeyda öztürk
Migraine Disorders
A Study of Lasmiditan in Participants With Migraine
The purpose of this study is to measure how much of the drug gets into the blood stream and how long it takes the body to get rid of it during an acute migraine attack and also during the time between acute migraine attacks.
- Trial name
- NCT03247790
- Testing
- Lasmiditan
- Where
- 3 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraines
Quantitative Sensory Testing and Occipital Nerve Stimulator
The primary aim of this study is to assess the reversibility of a range of psychophysical markers of pain processing in patients with chronic migraine or cluster headache before and after ONS insertion and comparing to patients…
- Trial name
- NCT06022848
- Testing
- occipital nerve stimulator
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust