Clinical trials: Healing
PVD, Arterial Ulcers
Effect of HPIPC for the Treatment of Ischemic Ulcers in Subjects With PAD
To evaluate the effects of HPIPC for the treatment of symptoms of PAD
- Trial name
- NCT01420289
- Testing
- High pressure intermittent pneumatic compression (HPIPC), Excercise
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Calvary Hospital, Bronx, NY
Diabetic Foot Ulcer t, Type 1 Diabetes Mellitus
"Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds"
This study aims to evaluate whether using ultrasound (phonophoresis) can help deliver propolis-a natural compound made by bees-more effectively into the skin to speed up wound healing in people with diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcer t, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Wound Management
- Trial name
- PEARL (NCT07099482)
- Testing
- Propolis gel (10%)
- Volunteers
- 80 people
- Sponsor
- Sinai University
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Postoperative Pain, Cesarean Section
Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune…
- Conditions
- Postoperative Pain, Cesarean Section, Wound Heal
- Trial name
- NCT05840406
- Testing
- Postoperative pain management with acetaminophen, Bilateral TAP Block with levobupivacaine, Bilateral TAP Block with levobupivacaine and dexmedetomidine
- Where
- Croatia
- Volunteers
- 105 people
- Sponsor
- University Hospital Sestre Milosrdnice
Periodontitis
Polynucleotide + Hyaluronic Acid Gel With Xenogeneic Graft for Intrabony Periodontal Defects
Over the last 30 years, the prevalence of periodontitis (PE) has increased substantially, including among younger populations, highlighting the need to improve the management of this condition as a chronic disease and to develop…
- Trial name
- NCT07522684
- Testing
- Polynucleotide and hyaluronic acid-based gel, Control, Xenogeneic bone graft
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- University of Sao Paulo
Wound Heal
The Effects of Ozone Therapy on Wound Healing
the aim of present study was to evaluate effects of ozone therapy on wound healing after gingivectomy and gingivoplasty operations as a model of secondary wound healing..
- Trial name
- NCT03655158
- Testing
- ozone device ( Ozonytron XL )
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Peri-Implantational Loss, Surgical Wound
Strip Graft w/ Xenogeneic Matrix vs Free Gingival Graft for the Augmentation of Peri-implant Keratinized Mucosa
The primary objective of this study is to compare changes in peri-implant keratinized mucosa (PIKM) following the application of apically repositioned flap (ARF) using a combination of a Strip graft and a Xenogeneic matrix, or…
- Conditions
- Peri-Implantational Loss, Surgical Wound, Healing Surgical Wounds, Thin-gingiva
- Trial name
- NCT06261268
- Testing
- Strip graft with Mucograft, Free gingival graft
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Elective Reconstructive Surgery Population
The Effect of Healing Touch on Sleep
Healing Touch improves measures of sleep the night prior to surgery, thus improving surgery-related morbidity.
- Trial name
- Sleep7 (NCT01870076)
- Testing
- Healing Touch, Control, Presence
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Anal Fissure
An Open Label Multi-Dose Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing
This is an open label study. The study will consist of 2 treatment group: coated Nifedipine suppository containing 12 mg of Nifedipine applied twice daily (group 1) and coated Nifedipine suppository containing 12 mg of Nifedipine…
- Trial name
- NCT02023047
- Testing
- Nifedipine 12 mg coated suppositories
- Where
- 4 sites in Israel
- Volunteers
- 33 people
- Sponsor
- RDD Pharma Ltd
Forearm Fracture, Clavicle Fracture
Bone Ultrasound to Access Fracture Healing
The purpose of this study is to evaluate sequential fracture healing with radius/ulna fractures or clavicle fractures and compare ultrasound to radiographs.
- Trial name
- NCT02769117
- Testing
- Ultrasound on fractured bone, Ultrasound on contralateral intact bone
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Coronary Artery Stenosis
COmplex BifuRcation Lesions: A Comparison Between the AXXESS Device and Culotte Stenting: An Optical Coherence Tomography (OCT) Study
The aim of this study is to compare vessel healing at 9 months using OCT imaging for two different treatment techniques for treating bifurcation lesions.
- Trial name
- COBRA (NCT00895791)
- Testing
- AXXESS Biolimus A9-eluting bifurcation stent, culotte stenting (Xience V)
- Where
- Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gingival Recession
Evaluation of Cyanoacrylate as an Alternative to Sutures in Free Gingival Graft Stabilization
Free gingival graft (FGG) is a widely used periodontal plastic surgery technique for treating gingival recession, increasing keratinized gingiva width, and enhancing peri-implant soft tissues.
- Trial name
- NCT06821984
- Testing
- FGG secured using cyanoacrylate tissue adhesive without sutures.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Clinical and Radiographic Success in 6 Months
Clinical And Radiographic Efficacy Of MTA Flow In Apicoectomy
The goal of this observational study is to learn about the short-term effects of MTA flow thick material in apicoectomy treatment. Participants are patients who take MTA flow to treat their apical lesion.
- Trial name
- NCT07254143
- Testing
- MTA flow material
- Where
- Vietnam
- Volunteers
- 16 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Periodontal Pocket, Impacted Third Molar Tooth
Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery
This study evaluates the effectiveness of using Mineralized Plasmatic Matrix and β-tricalcium phosphate that placed to extraction socket as a graft material in terms of periodontal damage occurred in the distal aspect of the…
- Conditions
- Periodontal Pocket, Impacted Third Molar Tooth, Impacted Teeth With Abnormal Position
- Trial name
- NCT04366635
- Testing
- Impacted third molar surgery, Application of mineralised plasmatic matrix, Application of β-tricalcium phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Furcation Defects
Effect of Two Irrigation Protocols Applied Prior to Furcation Repair
Perforations are mishaps that might occur during the course of endodontic treatment mainly due to iatrogenic factors. However, they might also occur due to extensive decay of dentinal structure.
- Trial name
- NCT06757660
- Testing
- Furcation Repair
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Hypertensive Disorder of Pregnancy
Thriving Hearts: Healing-Centered, Integrated, Community Maternity Care
The overarching goal of Thriving Hearts is to implement a multi-level program through Local Health Departments (LHDs) that cultivates conditions for mothers and birthing people to not only survive pregnancy, but to thrive.
- Trial name
- NCT06744231
- Testing
- Usual Care, Thriving Hearts
- Where
- United States
- Volunteers
- 17,500 people
- Sponsor
- University of North Carolina, Chapel Hill
Apical Periodontitis
Effect of Passive Ultrasonic Irrigation Versus Needle Irrigation on Postoperative Pain and Periapical Healing
The aim of this study is to compare the effect of passive ultrasonic irrigation versus needle irrigation on post-operative pain and healing in patients with permanent posterior teeth with apical periodontitis treated in a single…
- Trial name
- NCT02913937
- Testing
- Passive ultrasonic irrigation, Endodontic needle
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Comparison of the Effects of Injectable Platelet-rich Fibrin and Low-dose Laser Applications on Palatal Wound Healing.
The investigators will evaluate the findings related to pain and bleeding, quality of life after surgery, and wound healing in participants who received injectable platelet-rich fibrin (i-PRF) and low-dose laser therapy to the…
- Trial name
- NCT06744270
- Testing
- i-PRF group, low-dose laser group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Esra Bozkurt
Periodontitis
Evaluation of the Effects of Immune Cells on Periodontal Healing
Periodontitis is an inflammatory disease with an infectious character, where, as the result of the host response to a dysbiotic microflora, attachment and bone loss occur.
- Trial name
- EMTA (NCT04792372)
- Testing
- Initial periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Biruni University
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