Clinical trials: Healing
Wound Healing
Safety and Efficacy of Topical TolaSure on Skin Punch Biopsies in Healthy Participants
TolaSure is a topical gel for the promotion of wound healing. This phase I study will assess the safety, tolerability and clinical effect of TolaSure when applied to skin wounds created by punch biopsy in healthy participants.
- Trial name
- NCT03620175
- Testing
- TolaSure Topical Gel
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- BioMendics, LLC
Healthy
Clinical Evaluation of the Photoallergy Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes photoallergic reactions on the skin.
- Trial name
- NCT00645164
- Testing
- Ointment Vehicle, Xenaderm
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Attention Deficit Hyperactivity Disorder
Healing Minds: Biofeedback and Breathing Practices in Children and Adolescents With ADHD
The objective of this research proposal is to examine the combined effects of an integrative approach including biofeedback and breathing practices (Healing Minds) on severity of Attention Deficit Hyperactivity Disorder (ADHD) in…
- Trial name
- NCT06648252
- Testing
- Healing Minds Biofeedback and Breathing Practices Intervention
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Diaper Rash
A Clinical Study to Assess the Efficacy and Safety of a Healing Ointment on Diaper Rash
The goal of this clinical trial is to assess the efficacy and safety of a Healing Ointment in infants 2-24 months with mild to moderate diaper rash.
- Trial name
- NCT06015217
- Testing
- "Cetaphil Healing Ointment"
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation
Study is intended to evaluate safety and efficacy parameters in patients treated with GLYC-101 gel or placebo after laser ablation.
- Trial name
- NCT00656474
- Testing
- GLYC-101 gel (1.0 %)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Chronic Wounds
Stromal Vascular Fraction From Lipoaspirate to Treatment of Chronic Non-healing Wound
This is a Phase I, open-label, single arm study to demonstrate the safety of Antria Cell Preparation Process during fat grafting augmented with autologous adipose derived stromal vascular fraction to demonstrate the safety and…
- Trial name
- NCT03882983
- Testing
- Antria Cell Preparation Process
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Antria
Skin Barrier Function, Wound Healing
Clinical Observational Study on Changes in Skin Physiological Parameters Following Ablative and Non-Ablative Fractional Laser Treatment at Different Doses
This clinical observational study investigates the dose-response relationship between laser energy intensity and skin damage/repair by applying different parameter sets of fractional ablative (CO2) and non-ablative (M22) lasers…
- Trial name
- NCT07561242
- Testing
- Ablative Fractional Carbon Dioxide Laser, Non-ablative Fractional Laser (1565 nm)
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Cicatrix, Wound Healing
Genomic Changes Associated With the Use of Intradermal Avotermin (Juvista) in Small Wounds in Healthy Male Subjects
The purpose of this study is to further determine the safety and toleration of intradermal avotermin (Juvista), confirm accelerated healing and investigate genomic expression profiles
- Trial name
- NCT00977951
- Testing
- Intradermal avotermin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Renovo
Scar, Wound Healing
Dose Regimen Study of SLI-F06 in Healthy Volunteers
Multi-center, dose-regimen, double-blind study evaluating the safety and efficacy of 4 doses of SLI-F06 compared with vehicle for improvement in scar appearance
- Trial name
- NCT05501327
- Testing
- SLI-F06
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Scarless Laboratories, Inc.
Cicatrix, Wound-healing
Investigation Into the Safety and Scar-improvement Efficacy of Intradermal Juvidex Dosed Once or Three Times
The purpose of this study was to investigate the scar-improvement efficacy of three doses of intradermal Juvidex given once only or three times in male and female subjects and to collect further safety and tolerability data for…
- Trial name
- NCT00984516
- Testing
- Juvidex
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Renovo
Non-healing Wounds
Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.
Single center pilot study examining the effect of Natrox topical oxygen therapy on chronic wounds along with the introduction of remote monitoring and telehealth for home care management.
- Trial name
- NCT04746573
- Testing
- Natrox Topical Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inotec AMD Limited
Scarring, Impaired Wound Healing
Effect of Collagenase on Healing and Scarring
A study to compare the rate of complete wound closure and quality of resulting scar at 3, 6 and 9 months, between dermatome-induced skin wounds treated with Collagenase Santyl Ointment versus vehicle alone.
- Trial name
- NCT00651820
- Testing
- Collagenase Santyl, Collagenase Santyl Vehicle
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Effect of Test Articles on the Healing of a Wound Artificially Induced by Liquid Nitrogen Spray
Study to Determine if Fibrin Affects the Ability of a Wound to Heal
The objective of this study is to evaluate the potential inhibitory effects of HP802-247 Vehicle on wound closure (healing), by comparing mean days to closure of superficial (partial-thickness) thermal wounds against similar…
- Trial name
- NCT01253135
- Testing
- Fibrin, White Petrolatum
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Erectile Dysfunction
Wound Healing Following Penile Prosthesis Implant
This is a prospective, randomized, clinical study aimed to evaluate the safety and efficacy of the two treatment schedules on men undergoing penile implant surgery for the first time.
- Trial name
- NCT05196191
- Testing
- VIAGENEX Max, Hibiclens wash
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Wound Healing
Impact of Silicon-based Formulations on Wound Healing of Laser-induced Microscopic Skin Lesions
Delayed wound healing is considered a health problem with devastating consequences for patients, healthcare systems, and societies.
- Trial name
- SPASM11 (NCT05614557)
- Testing
- Stratacel, Stratamed
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stratpharma AG
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation
The primary objectives of this study are to evaluate safety and efficacy of topically applied Glucoprime gel (GLYC-101, 0.1% and GLYC-101, 1.0%) in promoting wound healing in cosmetic surgery patients undergoing Carbon Dioxide…
- Trial name
- NCT00792688
- Testing
- GLYC-101 Gel (0.1%), GLYC-101 Gel (1.0%)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Wound Healing
A Study to Assess Wound Healing Efficacies of Different Clean, Treat, and Protect Wound Care Regimens Compared to Standard of Care and Untreated
The purpose of this study is to evaluate the healing rates of wounds treated with various wound care regimens including antiseptic wound wash, topical antibiotic treatment, adhesive bandages, and/or hydrocolloid bandages.
- Trial name
- NCT05045183
- Testing
- SoC Adhesive Bandage, Antibiotic Ointment, Antiseptic Wash
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Cicatrix, Wound Healing
Safety and Efficacy Study of Avotermin (Juvista) in Female Subjects
To assess safety and toleration, systemic exposure and anti-scarring potential of intradermal avotermin (Juvista) in young females.
- Trial name
- NCT00984581
- Testing
- Avotermin
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Renovo
Wounds
Platelets for Acute Wound Healing
This study will examine whether platelet gel positively affects wound healing. Platelet gel will be used to treat punch biopsy wounds and the results will be compared to results from wounds treated with a control treatment.
- Trial name
- NCT00125086
- Testing
- autologous platelet gel
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Medtronic
Cicatrix, Wound-healing
Investigation of the Efficacy of Zesteem in Accelerating Early Wound Healing
The purpose of this study is to investigate early wound healing of one application of four different doses of intradermal Zesteem (17β-Estradiol) in male subjects and female subjects two years post-menopausal.
- Trial name
- NCT00984386
- Testing
- Zesteem
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Renovo