Clinical trials: Healing Fracture of Bone
Infection
VeraFlo With Prontosan® and Wound and Fracture Healing.
To answer the question: "Do Prontosan instillations decrease time to wound and fracture healing and decrease bacterial load compared to wound vac treatment without Prontosan?," we will enroll up to 30 subjects (for an anticipated…
- Trial name
- NCT02621073
- Testing
- VeraFlo with Prontosan, V.A.C Ulta System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Brett Crist
Tooth Loss, Tooth Injury
Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients
This study aims to evaluate the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients.
- Trial name
- YATA (NCT07314580)
- Testing
- Premolar Autotransplantation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Radius Fractures
Association Between Hand-Eye Coordination and Handgrip Strength in Children Post-Healing of DRGF
The study investigates whether hand-eye coordination is related to handgrip strength in children (aged 5-12 years) after they have healed from distal radius greenstick fractures.
- Trial name
- NCT07037355
- Testing
- Handgrip Strength and Hand-Eye Coordination Assessment
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Superior University
Bone Fracture
Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II
The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as an autologous bone-regenerating graft in the reconstruction of deficient bone in two clinical indications: 1.
- Trial name
- NCT03024008
- Testing
- BonoFill-II
- Where
- 6 sites in Israel
- Volunteers
- 40 people
- Sponsor
- BonusBio Group Ltd
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Avulsion
Healing Assessment of External Inflammatory Root Resorption After Revascularization Technique of Avulsed Permanent Central Incisor (Case Study)
Evaluate the healing of external root resorption of replanted avulsed permanent maxillary central incisor after revascularization.
- Trial name
- (EIRR) (NCT06785961)
- Testing
- Regeneration of traumatic tooth
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Badr University
Femoral Fracture
Fracture Monitor - Femur
Thirty-seven patients diagnosed with femoral fracture to be treated with a compatible plate will be enrolled for this multicenter prospective interventional study.
- Trial name
- NCT05410587
- Testing
- Fracture Monitor (implantable device class III)
- Where
- 4 sites in Germany
- Volunteers
- 37 people
- Sponsor
- AO Innovation Translation Center
Colles' Fracture
Effects of Teriparatide on Distal Radius Fracture Healing
Effects of Teriparatide on Distal Radius Fracture Healing
- Trial name
- NCT00190944
- Testing
- Teriparatide
- Where
- 7 sites in United States, Mexico and 3 more
- Volunteers
- 105 people
- Sponsor
- Eli Lilly and Company
Long Bone Delayed-Union Fracture
Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures
Fracture healing is a complex physiological process caused by interaction of cellular elements, cytokines and signaling proteins, which results in the formation of new bone.
- Trial name
- NCT02020590
- Testing
- ALLOB® implantation
- Volunteers
- 25 people
- Sponsor
- Bone Therapeutics S.A
Sternum Wound Infection, Nonunion of Fracture of Sternum
Sternal Closure With STERNUMFIX in Patients With High Risk
The primary objective is to establish if the SternumFix System improves sternal closure. The study should test the hypothesis that in a high risk patient population with increased risk for the development of sternal wound…
- Trial name
- STEPHIX (NCT01408745)
- Testing
- Sternumfix, steel wire
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 166 people
- Sponsor
- Aesculap AG
Fracture
Evaluation of Treatment of Fractures of the Humerus With a Plate.
The purpose of this study is to study with the use of clinical and radiological parameters the treatment of three-part and four-part fractures with the Winsta PH osteosynthesis device (Fischer Medical).
- Trial name
- NCT00408291
- Testing
- Winsta PH osteosynthesis device
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Humeral Fracture
Does Teriparatide (rhPTH 1-34) Promote Fracture Healing in Proximal Humeral Fractures?
40 postmenopausal women, with a non-operated proximal humeral fracture, will be randomized to standard treatment (physiotherapy) or standard treatment + Forsteo (rhPTH 1-34) during 4 weeks.
- Trial name
- NCT01105832
- Testing
- Teriparatide
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- University Hospital, Linkoeping
Hip Fractures
Vibration Therapy as an Intervention for Enhancing Trochanteric Hip Fracture Healing in Elderly Patients
Currently, there are approximately 300,000 hip fractures per year in the US with a mortality rate of 20% within 1 year. In Hong Kong, around 6,000 hip fractures occur yearly with costs approximately 52 million USD, and these…
- Trial name
- NCT04063891
- Testing
- Low-magnitude high-frequency vibration (LMHFV)
- Where
- Hong Kong
- Volunteers
- 83 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng
Fractures
The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in children with fractures or those who have surgery to correct bony deformity requiring the bone to be cut…
- Trial name
- NCT02076321
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Missouri-Columbia
Non-union of Fractures
Autologous Stem Cell Therapy for Fracture Non-union Healing
Do mesenchymal stem cells accelerate new bone formation in persistent non-unions.
- Trial name
- NCT02177565
- Testing
- carrier plus in vitro expanded autologous BMSCs
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Ankle Fractures, Fracture
Outcome of Rehabilitation Following Internally Fixed Ankle Fractures
The purpose of this study is to examine the effect of variations in practice, ranging from early functional rehabilitation to complete immobilsation in post operative patients with ankle fixation following fractures.
- Trial name
- NCT02160197
- Testing
- Aircast XP Walker boot, Plaster Immobilisation
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Colles' Fracture
Weekly Use of Teriparatide to Accelerate Healing of Distal Radius Fracture
The purpose of this study is to examine the effect of weekly dosing strategy on fracture healing.
- Trial name
- NCT04473989
- Testing
- recombinant teriparatide for injection
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Fracture Healing, Vitamin D3
The Vitamin K2 and D3 Intervention Trial in Children and Adolescents With the Low-energy Fractures
a prospective, three- month, randomized, double-blind, placebo-controlled, intervention trial (RDBPC), investigating the effect of vitamin K2 (menaquinone-7) and vitamin D3 on the healing process of low-energy bone fractures in…
- Conditions
- Fracture Healing, Vitamin D3, Deficiency of Vitamin K2
- Trial name
- NCT03871322
- Testing
- Vitamin D and K2 supplementation, Vitamin D supplementation
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok