Clinical trials: Healing Fracture of Bone
Fractures
Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT)
This is a study designed to see if a low dose of Lithium treatment, taken for 2 weeks, can improve fracture healing and improve patients' function and productivity.
- Trial name
- LiFT (NCT02999022)
- Testing
- Lithium Carbonate
- Where
- 5 sites in Canada
- Volunteers
- 160 people
- Sponsor
- Sunnybrook Health Sciences Centre
Bone Regeneration, Periodontal Bone Loss
Effect of Nitroglycerin Hydrogel on Repairing Critical Bone Defects
Due to their osteoconductive, osteoinductive, and osteogenic qualities, autologous bone grafts are the gold standard for augmenting bone, (1).
- Conditions
- Bone Regeneration, Periodontal Bone Loss, Healing Fracture of Bone
- Trial name
- Nitro- Bone (NCT06925763)
- Testing
- Nitroglycerin
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Minia University
Hyperbaric Oxygen Therapy, Recovery Time
Hyperbaric Oxygen Therapy in Distal Radius Fractures: Can it Shorten Recovery Time and Increase Fracture Healing?
This project is meant to show wether the HBOT can fasten the recovery process after surgical treatment of distal Radius fractures.
- Conditions
- Hyperbaric Oxygen Therapy, Recovery Time, Contrast Media, Sonography
- Trial name
- HBOTRadius (NCT01365780)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Fracture Healing
Does Weightbearing Crutch Technology Impact Patient Compliance?
The goal of this study is to determine if weight-bearing crutch technology that delivers active feedback to patients during their treatment will impact patient compliance with physician instructions.
- Trial name
- NCT05825079
- Testing
- Weight-Bearing Feedback, Smart Crutch Tip
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Surgical Wound Infection
Clinical Assessment of Next Science Solution on Gustilo and Anderson Type II and IIIA or IIIB Tibial Fractures
This is a prospective, randomized, controlled, double-blinded clinical feasibility study of subjects that are being treated for Gustilo and Anderson Type II or IIIA or IIIB Tibial Fractures
- Trial name
- NCT04906642
- Testing
- Next Science, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Next Science TM
Femur Shaft Fracture, Tibia Fractures
Assessing Bone Fracture Healing Effect of Almonds
Femur and tibia shaft fractures are common after trauma with a burden of 5% and 20% respectively. Clinicians recommend costly bone strengthening drugs/supplements while treating bone fractures.
- Conditions
- Femur Shaft Fracture, Tibia Fractures, Vitamin D, Sweet Almonds
- Trial name
- AFHEA (NCT07153302)
- Testing
- Prunus dulcis (sweet almonds)
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Bone Regeneration, Fracture Healing
Procurement of Tissue Samples for Cell Cultures and Analyses
This study will determine if bone marrow stromal cells can be used as a graft for regeneration of bony defects. These cells have the ability to form new bone and to support the formation of blood.
- Conditions
- Bone Regeneration, Fracture Healing, Cell Culture Techniques, Tissue Engineering
- Trial name
- NCT00435877
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tibial Fractures, External Fixation Pin Site Infection
Real Life Weight Bearing After Tibial Fractures
In this prospective case series patients with a tibial fracture are monitored with smart biofeedback systems to document the healing progression and real life weight.
- Trial name
- NCT03166267
- Testing
- External fixator
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- AO Innovation Translation Center
Non-union or Delayed Healing Fractures
Evaluation of the Risk for Radiographic and Clinical Nonunion in Patients With Previous Bisphosphonates Therapy.
Dose and duration of bisphosphonate therapy will increase the likelihood that patients experience delayed healing of non-union fractures.
- Trial name
- NCT01731535
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Fracture Healing, Atrophic Non Union Development
Arginine and Nitric Oxide (NO) Early Prognostic Markers for Non-union Development
Objective: Primary objective is to study the arginine-NO metabolism during fracture healing and dysfunctional fracture healing. Secondary objective: to investigate if differences or decreased arginine and NO concentrations in…
- Conditions
- Fracture Healing, Atrophic Non Union Development, Hypertrophic Non Union Development
- Trial name
- NCT01070576
- Testing
- no intervention
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University Medical Center
Distal Femur Fractures
Radiostereometric Analysis of Fracture Healing in Distal Femur Fractures
The investigators are doing this research study to look at how distal femoral fractures (knee bone break) heal. In this study, the investigators will use Radiostereometric Analysis (RSA) to look at how the pieces of femur bone…
- Trial name
- RSA (NCT01593176)
- Testing
- Placement of RSA beads
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Distal Radius Fractures
Clinical Study on the Healing of Distal Radius Fractures With Conservative Treatment Assisted by Fu's Subcutaneous Needling
The goal of this clinical trial is to evaluate the efficacy and safety of Fu's subcutaneous needling (FSN) therapy combined with rehabilitation exercises in promoting fracture healing after conservative treatment of distal radius…
- Trial name
- NCT07054463
- Testing
- FSN Therapy Combined with Rehabilitation Training
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Guangzhou University of Chinese Medicine
Fracture Healing
Study To Assess FRacTure Healing With SclerosTin Antibody - Hip
This is an international, multi-center study to determine the efficacy, safety, and tolerability of romosozumab (AMG 785) in adults with a fresh unilateral hip fracture, status post surgical fixation.
- Trial name
- STARTT-Hip (NCT01081678)
- Testing
- Romosozumab
- Where
- 99 sites in United States, Argentina and 22 more
- Volunteers
- 332 people
- Sponsor
- Amgen