Clinical trials: Health
Cardiovascular Diseases
High Polygenic Risk and Health Behavior
The goal of this clinical trial is to evaluate the impact of awareness of high polygenic risk for CVD on health behavior among young overweight adults.
- Trial name
- INTERVENE (NCT05603663)
- Testing
- Informing study subjects about their high CVD polygenic risk score
- Where
- Estonia
- Volunteers
- 1,540 people
- Sponsor
- University of Tartu
HIV Infection
Evaluation of Behavioral Intervention for HIV Positive Prisoners in NC and TX
Purpose: The purpose of this study is to determine if a comprehensive intervention supporting seek-test-and-treat results in a significant reduction in the potential for HIV-infected prisoners to transmit their virus after…
- Trial name
- imPACT (NCT01629316)
- Testing
- Text reminders, counseling, and link coordination, Standard of care - control arm
- Where
- 2 sites in United States
- Volunteers
- 381 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Myocardial Infarction, STEMI
Delayed Educational Reminders in Acute Myocardial Infarction (MI)
ST segment elevation myocardial infarction (STEMI) is a common presentation of heart attack constituting approximately 30% of all cases.
- Trial name
- DERLA-STEMI (NCT01325116)
- Testing
- Educational Reminder
- Where
- Canada
- Volunteers
- 852 people
- Sponsor
- Hamilton Health Sciences Corporation
Type 1 Diabetes
The REPOSE (Relative Effectiveness of Pumps Over MDI and Structured Education) Trial
For type-1 diabetes, the aim of insulin therapy is to keep blood glucose close to normal while avoiding hypoglycaemia but this is severely limited by the relative crudeness of current insulin delivery in comparison with the…
- Trial name
- REPOSE (NCT01616784)
- Testing
- CSII (Insulin Pump) plus DAFNE, MDI (levemir® & quick acting insulin) plus DAFNE
- Where
- 8 sites in United Kingdom
- Volunteers
- 267 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
The Study is Focused on People With Limited Health Literacy, We Are Not Studying a Disease or Condition
(Cost)Effectiveness of the Intervention 'Gezond en Goed Met Elkaar'
The goal of this intervention study is to learn if the intervention can increase positive health and health literacy in people with limited health literacy.
- Trial name
- GGME (NCT06644547)
- Testing
- Gezond en goed met elkaar
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Hyposmia, Olfactory Dysfunction
Slow-SPEED UK: A Double-Blind Randomised Feasibility Trial
Slow-SPEED UK is an 18-month randomised, double-blind feasibility trial evaluating the delivery, adherence, and acceptability of a digitally supported physical activity programme in community-dwelling adults aged 40 and over with…
- Conditions
- Hyposmia, Olfactory Dysfunction, Anosmia
- Trial name
- Slow-SPEED (NCT06600438)
- Testing
- Slow-SPEED app
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- Queen Mary University of London
Smoking Cessation
Determinants of Smoking Cessation Among Latinos
The goal of this study is to learn how neighborhood and individual factors affect the ability to stop smoking among Spanish-speaking Mexican American (MA) smokers who want to quit smoking.
- Trial name
- NCT01008748
- Testing
- Nicotine Replacement Therapy (NRT), Questionnaire, Counseling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Nurse's Role
The Effect of Telenursing on the Pain and Fear of Insulin Injection
Aim: The aim of the study is to examine the effects of nursing follow-up with telenursing on the pain and fear factors related to self-injection testing in diabetic individuals who are started on insulin therapy for the first…
- Trial name
- NCT06013826
- Testing
- Telenursing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Saglik Bilimleri University
Obesity, Overweight
Eating Peanuts for Health
Evidence is accumulating that peanut consumption confers health benefits, such as reduction of cardiovascular disease risk and possibly diabetes risk (Jenkins et al., 2008; Mattes et al., 2008).
- Conditions
- Obesity, Overweight, Hyperlipidemia
- Trial name
- NCT01886326
- Testing
- Consumption of 42 grams of peanuts daily
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Purdue University
Pre-exposure Prophylaxis, HIV Prevention
UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study
The primary purpose of this study is to assess the safety of long-acting injectable cabotegravir (CAB-LA) and oral pre-expose prophylaxis (PrEP) (FTC/TDF or 3TC/TDF) for the prevention of HIV during pregnancy and breastfeeding…
- Conditions
- Pre-exposure Prophylaxis, HIV Prevention, Pregnancy Related
- Trial name
- PrIMO (NCT06158126)
- Testing
- Initiating daily oral PrEP during pregnancy, Already using daily oral PrEP at the time of pregnancy diagnosis, Initiating injectable PrEP during pregnancy
- Where
- Malawi
- Volunteers
- 621 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hypertension, Prehypertension
Use of Mobile Technology to Prevent Progression of Pre-hypertension in Latin American Urban Settings
Nearly half of the adult population in Latin American urban settings has abnormally high blood pressure. Although half of these subjects with high blood pressure are still in the pre-hypertensive stage (systolic blood pressure…
- Trial name
- NCT01295216
- Testing
- Mobile technology to promote lifestyle modification
- Where
- 3 sites in Argentina, Guatemala and 1 more
- Volunteers
- 637 people
- Sponsor
- Institute of Nutrition of Central America and Panama
Healthy Volunteer
MS PATHS Normative Sub-Study
The primary objective of this study is to determine the normative range of brain volume and brain volume change in healthy control (HC) participants whose age, race, and gender distribution is approximately matched to the age…
- Trial name
- NCT02996084
- Where
- 6 sites in United States, Germany and 1 more
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Biogen
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Mental Health Issue, Substance Use Disorders
IT to Support Integration of Social Determinant of Health Services to Reduce Avoidable Emergency Department Visits
Working through regional Accountable Care Organizations (ACO) the sponsor will establish a 2-year pilot project to demonstrate that early recognition and intervention in the various Social Determinant of Health (SDoH) domains can…
- Trial name
- NCT04125433
- Testing
- Peer Integrated Care Services
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Northern New York Rural Behavioral Health Institute
Childhood Obesity
Motivational Interviewing for Weight Loss
The investigators studied the effect of motivational interviewing (MI) on self-efficacy, health behaviors, and health outcomes in overweight children and adolescents (ages ranging from 10 to 18 years).
- Trial name
- NCT01246349
- Testing
- Motivational Interviewing (Treatment Group), Social Skills Training (Control Group)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Sedentary Behavior, Occupational Stress
Effects of a Sedentary Behaviors at Work on Health in Emergency Medical Dispatchers and CODIS Operators (SECODIS)
The purpose of the study is to study changes in sedentary behavior following a behavioral intervention (sit-and-stand desk, and cycloergometer)
- Trial name
- SECODIS (NCT05931406)
- Testing
- Control, Sit-and-stand desk, Cycloergometer
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Prostate Cancer
Prostate Cancer E-Health-Tutorial
In a participatory process involving urologists and former patients, the project team has developed an online information system ("tutorial") for patients with localized prostate cancer.
- Trial name
- PROCET (NCT02503748)
- Testing
- Online tutorial
- Where
- 8 sites in Switzerland
- Volunteers
- 53 people
- Sponsor
- Zurich University of Applied Sciences
Post-traumatic Stress Disorder, Alcohol Abuse
Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Recent needs assessments suggest that difficulties exist in care coordination between emergency medical services (EMS) systems and primary care for injured adolescents with alcohol problems and post-traumatic stress disorder…
- Conditions
- Post-traumatic Stress Disorder, Alcohol Abuse, Alcohol Dependence
- Trial name
- ATRSCC (NCT00619255)
- Testing
- Adolescent Trauma Support Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Any Disease or Condition, Healthy
UCSF Research Participant Registry
The UCSF Clinical and Translational Science Institute (CTSI) Consultation Service provides recruitment services and facilitates the enrollment of research participants into UCSF clinical studies.
- Trial name
- NCT01717378
- Where
- United States
- Volunteers
- 1,541 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Crohn Disease (CD), Ulcerative Colitis (UC)
TIDHI Mental Health in IBD Patients Study
The purpose of this study is to test the impact of Healing Circuits™; a structured mental health support model on IBD patients. The eligible study participants will be randomly divided into two groups: 1.
- Conditions
- Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- NCT07013578
- Testing
- Healing Circuits™ sessions, self-directed Healing Circuits™ curriculum
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- TIDHI Innovation Inc.