Clinical trials: Health Adult Subjects
Hypertension
Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Amlodipine and Losartan in Health Volunteers
The purpose of this study is to evaluate the comparative bioavailability of two fixed dose combination tablet formulations of amlodipine and losartan in healthy volunteers.
- Trial name
- NCT01648231
- Testing
- Reference Treatment: 1 x 5mg amlodipine tablet and 1 x 100mg losartan tablet administered in fasted state, Fixed Dose Combination 1: 1 x 5mg amlodipine / 100mg losartan tablet administered in fasted state, Fixed Dose Combination 2: 1 x 5mg amlodipine / 100mg losartan tablet administered in fasted state
- Where
- Australia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Health Adult Subjects
A Study to Evaluate the Safety, Immunogenicity, and Pharmacokinetics of GR2303 in Healthy Adult
he goal this clinical trail is to evaluate the safety、Pharmacokinetic and immunogenicity of GR2303 injection。 Subjects will be enrolled in different groups in sequential order, and within each group will be randomly assigned to…
- Trial name
- NCT07199270
- Testing
- GR2303 injection
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Circadian Rhythm, Health Adult Subjects
Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise
This cross-sectional, observational, and analytical study aims to investigate the relationship between morningness-eveningness characteristics and cardiovascular recovery after a submaximal exercise test in healthy individuals…
- Trial name
- NCT07833956
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Health Adult Subjects
Eight-week Sports Injury Prevention Program
This study aims to find out whether an 8-week sports injury prevention program can improve lower-body performance-such as power, agility, and balance-among female college athletes in Saudi Arabia.
- Trial name
- NCT07270614
- Testing
- 8-Week Sports Injury Prevention Program
- Where
- Saudi Arabia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Health Adult Subjects
Prefrontal Neuroplasticity and Coping Strategies in Healthy Population
The current study serves as a pilot for the GRF project "Predicting illness trajectories in fully remitted major depression using concurrent TBS/fNIRS." The project examines whether intermittent theta-burst stimulation (iTBS)…
- Trial name
- NCT07433829
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Neurological Disorders, Health Adult Subjects
A Multicenter Interventional Study on the Use of a 3-Degree-of-Freedom (3DOF) Platform to Evaluate the Safety and Usability of the System and Its Impact on Balance, Proprioception, and Neurological Deficits in the Rehabilitation of Patients With Neurological Disorders.
This multicenter interventional study aims to evaluate a three-degrees-of-freedom dynamic platform (3DoF Platform) designed to support rehabilitation of balance, proprioception, and motor and cognitive functions in patients with…
- Trial name
- 3DOF (NCT07502937)
- Testing
- 3DOF balance board robotic platform group, Conventional Rehabilitation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Amyotrophic Lateral Sclerosis, Health Adult Subjects
Alter-Ego as an Assistive Robotic Device.
The ALTER-EGO study is a monocentric, observational clinical investigation designed to evaluate the safety, usability, and feasibility of the humanoid robotic platform Alter-Ego as an assistive device in hospital and simulated…
- Trial name
- Alter-Ego (NCT07572838)
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Pisa
Health Adult Subjects
Pre-Exercise Mood and Physiological Responses to Maximal Effort in Elite Rowers
This study examined how the body and mood respond to intense physical effort in elite male and female rowers. Athletes completed a maximal rowing test after one week of hard training.
- Trial name
- 6000MFPOMS2024 (NCT07243613)
- Testing
- Maximal Rowing Test
- Where
- Poland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Dental Caries, Tooth Demineralization
Effectiveness of Two Health Education Interventions in the Prevention of Caries and Gingivitis in Orthodontic Patients
Dental caries and gingivitis are classified by the World Health Organization (WHO) as an important public health problem due to their high prevalence and incidence worldwide despite the development of public policies to combat…
- Conditions
- Dental Caries, Tooth Demineralization, Gingivitis
- Trial name
- NCT05979805
- Testing
- Conventional Educational interventions, Motivational intervention
- Where
- Colombia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Health Adult Subjects
Effects of NR Supplementation on Metabolic Flexibility in Zone 2 Training
Zone 2 training, a low-intensity endurance exercise performed at approximately 66-80% of VO₂max or near the first ventilatory threshold, has gained popularity for improving aerobic capacity, fat metabolism, and mitochondrial…
- Trial name
- NCT07344636
- Testing
- Nicotinamide Riboside (NR)
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ZHANG Jiaqi
Healthy, Constipation
Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms
First experimental study (Proof Of Concept) to investigate bowel function parameters on which a fermented milk product with probiotics alone or in association with fibers has a potential effect.
- Trial name
- NCT02461485
- Testing
- Fermented milk product containing Probiotics, Fermented Milk Product containing Probiotics + Fibers C, Fermented Milk Product containing Probiotics + Fibers W
- Where
- Ireland
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Typhoid Fever
Safety and Immunogenicity of Three Formulations of Vi-CRM197 Vaccine Against S. Typhi in Adults (18-40 Years Old)
This trial is aimed to evaluate the safety and immunogenicity profiles of three formulations of Vi-CRM197 conjugate vaccine against S.
- Trial name
- NCT01193907
- Testing
- NVGH Vi-CRM197 12.5 mcg, NVGH Vi-CRM197 5.0 mcg, NVGH Vi-CRM197 1.25 mcg
- Where
- Belgium
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Novartis
Healthy Adult Participants
EVASTRESS Healthy Subjects
The goal of this observational study is to learn the feasibility of using a mobile application "Stressometer" to measure perceived stresss levels several times per day.
- Trial name
- EVASTRESS HS (NCT07592078)
- Testing
- Stressometer Mobile Application
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Rheumatoid Arthritis
A Multicentre Trial to Determine the Efficacy of AD 452 in RA Subjects.
AD 452 is a new drug which is being developed for use in adult patients with RA. It is believed that AD 452 may modify the underlying disease of RA as well as improving RA symptoms, and in order to establish its efficacy and…
- Trial name
- NCT00141934
- Testing
- AD 452
- Where
- 10 sites in United States
- Volunteers
- 232 people
- Sponsor
- Sosei
Social Anxiety Disorder (SAD)
Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-4)
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute intranasal (i.n.) administration of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to relieve symptoms of acute anxiety in…
- Trial name
- PALISADE-4 (NCT06615557)
- Testing
- Fasedienol Nasal Spray
- Where
- 26 sites in United States
- Volunteers
- 238 people
- Sponsor
- VistaGen Therapeutics, Inc.
Health Adult Subjects
A Phase Ia Single Ascending-Dose Study of Subcutaneous EB070 Injection in Healthy Volunteers
The goal of this Phase Ia clinical trial is to evaluate the safety, tolerability, and pharmacokinetics of EB070 injection following single ascending subcutaneous doses in healthy adult volunteers.
- Trial name
- NCT07413536
- Testing
- EB070
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biotech Pharmaceutical Co., Ltd.
Obesity Adult Onset
Gut Microbiota, Mitochondrial Function and Metabolic Health in Obesity
It has been suggested that individuals with the condition known as metabolically healthy obesity (MHO) may not have the same increased risk of developing metabolic abnormalities as their non-metabolically healthy counterparts.
- Trial name
- NCT06279780
- Testing
- very low-calorie diet
- Where
- Spain
- Volunteers
- 109 people
- Sponsor
- Celia Bañuls
Bioequivalence, Diabetes Mellitus, Type 2
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of sitagliptin/metformin extended release tablets after a single oral dose…
- Trial name
- NCT06124547
- Testing
- Sitagliptin/Metformin HCl 50/500 mg extended release film-coated tablet
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
Health Adult Subjects, Exercise-Induced Changes in Gastrocnemius Muscle Stiffness
Acute Changes in Gastrocnemius Muscle Stiffness
This study evaluated how different exercise and rest schedules during calf-raise exercise affected the stiffness of the calf muscle in trained volleyball athletes.
- Trial name
- NCT07745452
- Testing
- 30-Second Work / 30-Second Rest Calf-Raise Protocol, 15-Second Work / 45-Second Rest Calf-Raise Protocol, 45-Second Work / 15-Second Rest Calf-Raise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Health Adult Subjects
Movement Quality and Mechanical Properties of the Muscle
Movement quality is considered a comprehensive indicator of neuromuscular control, segmental stability, and efficient force transmission, and is recognized as an important determinant of musculoskeletal health and functional…
- Trial name
- NCT07468981
- Testing
- Healthy Subjects
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University