Clinical trials: Health Behavior / Well-Being
Tobacco Use Cessation
Telephone Counseling for Tobacco Cessation
The purpose of this study is to determine whether giving more structured information to patients over the phone about quitting tobacco helps to increase the chance that they will try to quit.
- Trial name
- NCT01489579
- Testing
- Telephone Counseling for Tobacco Cessation, Usual Care
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Lung Cancer, Medication Adherence
Implementation Strategies for Monitoring Adherence in Real Time
The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.
- Conditions
- Lung Cancer, Medication Adherence, Symptoms and Signs
- Trial name
- iSMART (NCT04347161)
- Testing
- Conversational Agent/Chatbot, Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Depression
An Adaptive Intervention for Depression Among Latinos Living With HIV
This study will use a pilot sequential multiple assignment randomized trial (SMART) design to build an adaptive treatment strategy (ATS) for depression and engagement in HIV among Latinos living with HIV.
- Trial name
- Latino-SMART (NCT03668379)
- Testing
- Augment w/mHealth, Maintenance, Switch to CBT & mHealth
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Major Depressive Disorder, Nicotine Dependence
Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms
The primary purpose of this study is to determine whether, among smokers with elevated depressive symptoms, sequential antidepressant pharmacotherapy with fluoxetine (20 mg) begun 8 weeks prior to and extended throughout standard…
- Conditions
- Major Depressive Disorder, Nicotine Dependence, Depression
- Trial name
- NCT00578669
- Testing
- Fluoxetine, Dextrose
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Smoking Cessation, Pregnancy
Phone-Based Postpartum Continuing Care for Smoking Cessation
Smoking is a leading cause of death and other negative health outcomes. While a high percentage of women quit smoking during pregnancy, the majority relapse in the first 6 months postpartum.
- Trial name
- PPCC (NCT01684592)
- Testing
- Phone-based postpartum continuing care, Standard care
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Battelle Memorial Institute
Cognitive Change, Health Behavior
A Multidomain Approach to Preventing Dementia in African Americans: Cognitive Prescriptions
The goal of this R21 study is to explore the feasibility and preliminary efficacy of individualized cognitive prescriptions (CogRxs) in improving engagement in healthy behaviors and other outcomes in middle-aged AAs and to gain…
- Conditions
- Cognitive Change, Health Behavior, Health Literacy
- Trial name
- NCT03864536
- Testing
- Cognitive Prescriptions
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Reduction in Heavy Drinking in Patients With HIV
Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention
This is a double-blind placebo-controlled study to evaluate the effect of Naltrexone (NTX) and counseling on highly active antiretroviral treatment (HAART) medication adherence in a cohort of HIV-infected patients who report…
- Trial name
- DAWN (NCT01227044)
- Testing
- Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Yale University
Smoking Cessation
Personalized Smoking Cessation Tool Based on Patient Lung CT Image
Imbio is developing a Smoking Cessation Report (Report) that includes data analysis from a CT lung cancer screening exam. This randomized controlled (RCT) trial will clinically validate the Report's effectiveness at motivating…
- Trial name
- NCT03087617
- Testing
- Imbio Smoking Cessation Report, Smoking Cessation Counseling, Usual Care
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- Imbio
COVID-19 Vaccines, Telemedicine
Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool
This study will determine the effectiveness of a vaccine communication mobile health app on parental decisions to vaccinate their children against coronavirus disease 2019 (COVID-19).
- Conditions
- COVID-19 Vaccines, Telemedicine, Vaccine Hesitancy, Pediatric ALL
- Trial name
- MoVeUP (NCT05386355)
- Testing
- COVID-19 Vaccine Uptake App, General Health App
- Where
- 15 sites in United States
- Volunteers
- 1,934 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Pregnancy, Smoking
Self-Monitoring of Carbon Monoxide to Enhance Reproductive Outcomes in Women
Our goal is to study self-monitoring of smoking as a means to reduce smoking in pregnant women. Investigators hypothesize that more regular self-monitoring, text messages and feedback as provided by home carbon monoxide…
- Conditions
- Pregnancy, Smoking, Smoking Cessation
- Trial name
- NCT02246114
- Testing
- piCO+ Smokerlyzer® monitor, Text messages
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Vascular Access Complication
Prospective Feasibility Trial of AccuCath 2.25" Blood Control (BC) Placed in Difficult Access Patients in the Emergency Department
Study objective is to evaluate user preference, time for procedure, insertion success rates, complications, completion of therapy and dwell time of the AccuCath 2.25" BC device placed in difficult IV access patients in the…
- Trial name
- NCT02449798
- Testing
- AccuCath 2.25" BC Intravascular Catheter
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Urinary Tract Infection
Urinary Proanthocyanidin-A2 as a Biomarker of Compliance to Intake of Cranberry Products
This protocol is a clinical trial to validate proanthocyanidin A2 (PAC-A2) as a useful marker of cranberry intake. We hypothesize the consumption of this cranberry beverage in a progressive dosing schedule will increase PAC-A2…
- Trial name
- NCT01687114
- Testing
- cranberry juice
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tufts University
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation
Participants will be randomly assigned (like the flip of a coin) to one of the two groups after completing the baseline survey. Participants have a 50% of being in either the #EnufSnuff.TXT intervention group or the Enough Snuff…
- Trial name
- NCT04315506
- Testing
- #EnufSnuff.TXT Intervention, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking Cessation
Implementation of Smoking Cessation Within NCI Community Oncology Research Program (NCORP) Sites
Evaluate a multi-faceted training program to improve short-term smoking cessation rates (<14 days post-visit) and short (3 months) and sustained abstinence (6 months) among 1,114 enrolled smokers who present for low-dose computed…
- Trial name
- OaSiS (NCT03291587)
- Testing
- Personnel Training and Coaching Calls
- Where
- 49 sites in United States
- Volunteers
- 1,094 people
- Sponsor
- Wake Forest University Health Sciences
Quitting Smoking, Smoking Cessation
BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study
The purpose of this research study is to see if offering adult primary care patients who smoke combustible cigarettes more frequent outreach, more choices about how they receive that outreach, and more smoking treatment options…
- Conditions
- Quitting Smoking, Smoking Cessation, Smoking, Cigarette
- Trial name
- NCT05683821
- Testing
- Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral
- Where
- United States
- Volunteers
- 12,376 people
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation, Harm Reduction
Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction
This open-label study will explore the impact of varenicline on the process of switching from combustible cigarettes (CC) to an e-cigarette.
- Trial name
- EVAR (NCT04210180)
- Testing
- Varenicline, e-cigarette
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Tobacco Use Disorder
Social and Monetary Incentives for Smoking Cessation at Large Employers
The investigators will conduct a cluster randomized controlled trial of several behavioral interventions for smoking cessation among a sample of employees at large workplaces in the Bangkok metropolitan area.
- Trial name
- SMILE (NCT02421224)
- Testing
- Usual Care, Deposits, Small Individual Bonus
- Where
- Thailand
- Volunteers
- 4,190 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Major Depression
A Family-based Primary Care Intervention to Enhance Older Men's Depression Care
Despite the public health importance of clinical depression, more than 50% of depressed adults receive inadequate or no treatment, with even higher rates of under-treatment in men and minorities.
- Trial name
- NCT02143024
- Testing
- Family-based depression intervention, Usual care plus educational materials
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Davis
Depression, Pregnancy
mHealth for Antenatal Mental Health
The aim of this study is to determine the feasibility of using mobile technology for: 1. Implementing the recommendations of the Antenatal and postnatal mental health: clinical management and service guidance NICE guideline for…
- Trial name
- AMHS (NCT02516982)
- Testing
- Whooley Questions, Edinburgh Postnatal Depression Scale, Momentary questions
- Where
- 14 sites in United Kingdom
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cigarette Smoking
Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers
The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking
- Trial name
- NCT00843622
- Testing
- Low-nitrosamine smokefree tobacco product for oral use
- Where
- 4 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB
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