Clinical trials: Health Behavior / Well-Being
Depression, Information Dissemination
Community Partners in Care is a Research Project Funded by the National Institutes of Health
CPIC is a community initiative and research study funded by the NIH. CPIC was developed and is being run by community and academic partners in Los Angeles underserved communities of color.
- Conditions
- Depression, Information Dissemination, Social Determinants of Health
- Trial name
- CPIC (NCT01699789)
- Testing
- Quality Improvement Program, Resources for Services Expert Team, Community Engagement and Planning Council
- Where
- United States
- Volunteers
- 1,246 people
- Sponsor
- RAND
Smoking Cessation, Harm Reduction
Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction
This open-label study will explore the impact of varenicline on the process of switching from combustible cigarettes (CC) to an e-cigarette.
- Trial name
- EVAR (NCT04210180)
- Testing
- Varenicline, e-cigarette
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking, Smoking Cessation
Evaluation of Treatments to Improve Smoking Cessation Medication Adherence
Many smokers fail to take their smoking cessation medication as recommended. This research is designed to identify treatments that improve the use of cessation medications and to determine whether an increase in medication use…
- Conditions
- Smoking, Smoking Cessation, Adherence, Nicotine Dependence
- Trial name
- Adherence (NCT01120704)
- Testing
- Short Term Combination Nicotine Replacement Therapy (patch + gum), Long Term Combination Nicotine Replacement Therapy (patch + gum), Intensive Maintenance Counseling
- Where
- United States
- Volunteers
- 544 people
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation
The OneFlorida Cancer Control Alliance: Implementing the 6As in Pediatric Primary Care
The primary purpose of our study is to conduct a pilot, practice-based intervention focused on increasing adherence to the 6As for youth ages 11 through 17 years.
- Trial name
- NCT03044691
- Testing
- ResearchACTS software
- Where
- 3 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Health Care Utilization
Effect of Varied Outreach Methods on Appointment Scheduling and Appointment Completion Using MyChart
Our objective is to determine the effectiveness of varied outreach methods (e.g. standard versus tailored MyChart messaging) to children age 6-17 years old who are due for a WCC visit and don't have one scheduled in the next 45…
- Trial name
- NCT04994691
- Testing
- No Message, Standard message, Tailored message
- Where
- United States
- Volunteers
- 945 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Allergy;Food, Adherence, Treatment
The Food Allergy Superheroes Training (FAST) Program
Among children with a food allergy, strict avoidance (e.g., elimination of allergenic foods from one's diet) is the only intervention capable of preventing potentially devastating health-related sequelae including anaphylaxis and…
- Conditions
- Allergy;Food, Adherence, Treatment, Child, Only
- Trial name
- NCT04400214
- Testing
- Food Allergy Superheroes Training (FAST) Program, Food Allergy Knowledge Intervention
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Kent State University
Concussion, mTBI
Neurofeedback Impact on Veterans With mTBI
This study will evaluate neurofeedback (NFB) training as a low risk, non-invasive, effective treatment for Veterans diagnosed with mild traumatic brain injury (mTBI) and experiencing chronic post-concussive symptoms (PCSs).
- Conditions
- Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache
- Trial name
- NFBVETmTBI (NCT04195685)
- Testing
- Neurofeedback (NFB)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Medication Adherence
Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.
The purpose of this project is to test whether an online pain medication intervention is a feasible and effective way to increase opioid pain medication safety.
- Trial name
- NCT01770314
- Testing
- Experimental
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Inflexxion, Inc.
Urinary Tract Infection
Urinary Proanthocyanidin-A2 as a Biomarker of Compliance to Intake of Cranberry Products
This protocol is a clinical trial to validate proanthocyanidin A2 (PAC-A2) as a useful marker of cranberry intake. We hypothesize the consumption of this cranberry beverage in a progressive dosing schedule will increase PAC-A2…
- Trial name
- NCT01687114
- Testing
- cranberry juice
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tufts University
Adherence, Patient, Pre-Exposure Prophylaxis
mHealth Technologies to Enhance PrEP Adherence Among Thai MSM
This study aims to: 1) adapt the theory-based P3 (Prepared, Protected, emPowered) app designed to improve pre-exposure prophylaxis (PrEP) adherence, retention in PrEP clinical care, and PrEP persistence among young gay, bisexual…
- Conditions
- Adherence, Patient, Pre-Exposure Prophylaxis, HIV/AIDS
- Trial name
- P3-T (NCT04413708)
- Testing
- P3-T PrEP Adherence App
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Pain, Postoperative, Analgesics, Opioid
Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy
A blinded randomized control trial in living kidney donors. The study group will receive a liposomal bupivacaine Trans Quadratus Lumborum (TQL) block after the induction of general anesthesia.
- Conditions
- Pain, Postoperative, Analgesics, Opioid, Analgesics, Non-Narcotic, Physiological Effects of Drugs
- Trial name
- NCT03294109
- Testing
- Abdominal wall block with liposomal bupivicaine
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
COPD, Emphysema
The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD
COPD currently afflicts 24 million US residents; the prevalence of COPD is high among Veterans. Persons with COPD have significant functional disability as a result of the disease.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- WEB (NCT02099799)
- Testing
- Pedometer and Website
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Outcome Assessment, Patient Satisfaction
Evaluation of Factors Associated With Patient Satisfaction and Mood-State in Regional Anesthesia
Patient satisfaction is an important subjective measure of healthcare quality which contributes to evaluation of the structure, process and outcome of services.
- Trial name
- NCT03476278
- Testing
- Questionnaire
- Volunteers
- 300 people
- Sponsor
- Derince Training and Research Hospital
Diabetes
Caring Others Increasing EngageMent in PACT
This trial will compare two methods of increasing engagement in care and success in diabetes management, among patients with diabetes with high-risk features, who also have family members involved in their care.
- Trial name
- CO-IMPACT (NCT02328326)
- Testing
- CO-IMPACT, PACT
- Where
- 2 sites in United States
- Volunteers
- 478 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age
Despite marked reductions in cigarette smoking in the general population, smoking among economically disadvantaged women has increased.
- Trial name
- NCT04092387
- Testing
- Varying the nicotine content of cigarettes, E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Polypharmacy
Development & Pilot of the Technology-Enabled Alliance for Medication Therapy Management
The investigators will link community pharmacy and primary care practices via a shared electronic health record to improve medication therapy management for older patients taking complex prescription (Rx) regimens.
- Trial name
- TEAM (NCT04575155)
- Testing
- TEAM Strategy
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Northwestern University
Tobacco, Posttraumatic Stress Disorder
Improving Functional Outcomes of Veterans With PTSD and Tobacco Dependence
Veterans with PTSD have high rates of smoking (34%-86% vs. 18% in the general population) and have substantial difficulties with quitting tobacco.
- Trial name
- ACT-PT (NCT02576899)
- Testing
- Acceptance and Commitment Therapy for PTSD and Tobacco Use, Freedom From Smoking
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Medication Adherence, Bipolar Disorder
Ziprasidone Switching in Response to Adherence and Psychotropic-Related Weight Gain Concerns Among Patients With Bipolar Disorder (Zip Ad)
Psychotropic-related weight gain is a common concern among patients with bipolar disorder (BD). This concern affects an individual's satisfaction with treatment and may lead to reduced adherence and illness relapse.
- Trial name
- Zip Ad (NCT01293825)
- Testing
- ziprasidone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Adolescents, Mood Disorders
Mobile-enhanced Group CBT for Adolescents at Risk Severe Mood Disorders
Although cognitive-behavioral therapy (CBT) has shown efficacy in reducing symptoms and rates of mood relapse in adolescents at high risk for severe mood disorders (SMD; i.e., bipolar I/II disorder and recurrent or unremitting…
- Trial name
- NCT04887155
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of California, Los Angeles
Mental Health, Stress Disorders, Post-Traumatic
Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder
The primary study objective is to conduct a prospective, randomized controlled clinical trial that compares the effectiveness of two approaches for delivering smoking cessation treatment for veterans with posttraumatic stress…
- Conditions
- Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
- Trial name
- NCT00118534
- Testing
- Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 943 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs