Clinical trials: Health Behavior / Well-Being
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder
The Effects of Videogames on Depression Symptoms and Brain Dynamics
The purpose of the study is to evaluate the effects of a game-based digital-therapeutics (DTx) medical software device on the symptoms of depression in adults with confirmed major depressive disorder.
- Trial name
- NCT05426265
- Testing
- MEL-T01, MEL-S01
- Where
- 6 sites in Finland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Aalto University
Vaccine Refusal, Covid19
Project 2VIDA! COVID-19 Vaccine Intervention Delivery for Adults in Southern California
The United States (U.S.) is the country with the largest number of infections and deaths due to COVID- 19 and racial/ethnic minorities are disproportionately affected.
- Trial name
- 2VIDA! (NCT05022472)
- Testing
- COVID-19 Individual Awareness and Education., COVID-19 Community Outreach & Health Promotion., COVID-19 Individual Health Education & Linkages to Medical and Supportive Services.
- Where
- 6 sites in United States
- Volunteers
- 1,051 people, healthy volunteers welcome
- Sponsor
- Britt Skaathun
Smoking Cessation
Effect of Pre-op NRT on Peri-operative Complications and Long-term Abstinence: A Pilot Trial in Patients Undergoing CABG Surgery
This study will determine whether or not patients who use a Nicotine Replacement Therapy (NRT) patch prior to their by-pass surgery are more likely to be smoke-free 6 months after their surgery and have fewer post-operative…
- Trial name
- NCT02918500
- Testing
- Nicoderm Patch
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Quality of Life, Self Efficacy
Oral Health Education Interventions Among Seniors
The study aims to assess the efficacy of an oral health education group based activity versus an individual based oral health education activity in terms of changes in oral health related quality of life (OHRQoL), self-efficacy…
- Conditions
- Quality of Life, Self Efficacy, Knowledge
- Trial name
- NCT03301714
- Testing
- Oral Health Education
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Temple University
Systemic Lupus Erythematosus
Addressing Disparities in Lupus Care Through an Integrated Care Management Program
The aim of this study is to identify lupus patients receiving care at Brigham and Women's Hospital (BWH) who are at high risk for potentially avoidable acute care utilization, inconsistent ambulatory care use, and adverse…
- Trial name
- Rheum-iCMP (NCT03915652)
- Testing
- Rheum iCMP
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Brigham and Women's Hospital
Asthma
Asthma in Families Facing Out-of-pocket Requirements With Deductibles
Asthma is one of the most common chronic diseases in the U.S. Despite guidelines, adherence to recommended controller medications is low. Cost is an important barrier to adherence.
- Trial name
- AFFORD (NCT03175536)
- Testing
- HDHP with PDL
- Where
- United States
- Volunteers
- 12,238 people
- Sponsor
- Harvard Pilgrim Health Care
Post Traumatic Stress Disorder, Depression
Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive
The purpose of the study is to investigate whether an occupational therapy program could enhance mental health outcomes for veterans who SCUBA dive.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Stress, Psychological
- Trial name
- NCT03928392
- Testing
- SCUBA with Occupational Therapy (OT), Self-Contained Underwater Breathing Apparatus (SCUBA) without OT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Loma Linda University
Diet Modification, Substance Use Disorders
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
The purpose of this study is to test if a parenting program can be used to prevent substance use among Latino youth and at the same time promote healthy eating.
- Conditions
- Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor
- Trial name
- FPNG+ (NCT03517111)
- Testing
- Nutrition/substance use prevention, Substance use prevention only, Academic success program
- Where
- United States
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Childhood Cancer
SurvivorLink: Scalability of an Electronic Personal Health Record
Previous research suggests that children and adolescents with cancer are at heightened risk of late effects that can occur months or years after cancer treatment, yet little is known about programs that increase their return for…
- Trial name
- NCT03543852
- Testing
- SurvivorLink
- Where
- 12 sites in United States
- Volunteers
- 542 people
- Sponsor
- Emory University
HIV Infections, Stigmatization
Stigma, Risk Behaviors and Health Care Among HIV-infected Russian People Who Inject Drugs
This study is a randomized controlled trial (RCT) among 100 HIV-positive people with injection drug use, which aims to test the feasibility of the SCRIPT intervention and evaluate its effectiveness on the reduction of…
- Conditions
- HIV Infections, Stigmatization, Substance Use
- Trial name
- SCRIPT (NCT03695393)
- Testing
- ACT Therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Boston Medical Center
Smoking Cessation
Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention
The purpose of this study is to test the effects of a group smoking cessation program. The study will also examine individual differences in response to the intervention program.
- Trial name
- NCT02511236
- Testing
- Group Cognitive Behavioral Therapy, General Health Education, Transdermal Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hepatitis C, Chronic
Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C]
The primary objective of this pilot trial is to compare the efficacy, measured as sustained virologic response (SVR) at least 12 weeks after completion of therapy, across three study regimens/delivery modalities: Arm 1 - 4 weeks…
- Trial name
- NCT03480932
- Testing
- Sofosbuvir, Daclatasvir, Pegylated Interferon alfa-2a
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Birth Control Compliance
Acceptability of the NuvaRing Among Students
The ACCEPT study is a Phase IV trial in which women are randomized to either the NuvaRing® vaginal contraceptive ring or a low dose oral contraceptive to assess compliance, side effects, overall acceptability and intent to…
- Trial name
- ACCEPT (NCT00635570)
- Testing
- Ortho Tri-cyclen Lo, NuvaRing
- Where
- 3 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Depression
Participatory Design of Electronic Health Record Tools for Problem Solving Therapy
Problem Solving Therapy for Primary Care (PST-PC) is an evidence based psychosocial intervention (EBPI) for use in primary care settings, with more than 100 clinical trials.
- Trial name
- NCT03516513
- Testing
- Problem Solving Therapy as Usual, Assisted Problem Solving Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Adolescent Behavior
The P4 Intervention Study to Improve Adolescent Health
The primary objective is to conduct a pilot study to determine the efficacy of evidence-based interventions delivered in primary care clinic settings on parent-teen health communication.
- Trial name
- NCT02554682
- Testing
- Sexual Health, Alcohol Prevention, Teen Driving
- Where
- United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Tobacco Use Cessation, Smoking Behaviors
Interventions to Help More Low-income Smokers Quit
In a Hybrid Type 2 randomized trial, 1,980 low-income smokers from nine states with high smoking prevalence will be recruited from 2-1-1 helplines to receive either current standard practice (Quitline) or expanded services…
- Conditions
- Tobacco Use Cessation, Smoking Behaviors, Health Disparity
- Trial name
- SFH (NCT04311983)
- Testing
- Tobacco Quitline, Smoke Free Home
- Where
- United States
- Volunteers
- 1,973 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hepatitis C, Medication Adherence
Intensive Models of HCV Care for Injection Drug Users
Injection drug users (IDUs) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). HCV treatment leading to sustained viral response (SVR) is associated with increased survival.
- Trial name
- NCT01857245
- Testing
- Intensive Models (mDOT and CGT) of HCV Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Prisma Health-Upstate
Contraception, Contraceptive Usage
Contraception Navigator Program
The goal of this study is to pilot test the IN-Control Birth Control Navigator Program in Central Indiana for use by adolescents who would like to access birth control.
- Conditions
- Contraception, Contraceptive Usage, Health Care Utilization
- Trial name
- NCT05691270
- Testing
- IN-Control (Birth Control Navigator Program)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Indiana University
LGBTQ, Sexual Behavior
A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults
This study is to test the efficacy of an online CBT intervention (EQuIP) that addresses the pathways through which minority stress compromises LGBTQ young adults' co-occurring mental (e.g., depression) and behavioral (e.g.…
- Trial name
- NCT04408469
- Testing
- Online EQuIP, Self-monitoring control
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
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