Clinical trials: Health Care
Lower Respiratory Tract Infection
Approach for Optimizing Meropenem Therapy in Intubated and Mechanically-Ventilated, Adult Patients With Severe Gram-Negative Lower Respiratory Tract Infection
Antibacterial drugs are facing increasing limitations in terms of effectiveness due to emergence resistance. Improved antibacterial drug monitoring approaches are particularly needed in nosocomial infections occurring in ICU…
- Trial name
- MON4STRAT (NCT03915236)
- Testing
- MON4STRAT Strategy, Control group
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 7 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Substitution of Care
A Multicenter Research on the Effects of Substitution of Hospital Ward Care From Medical Doctors to Physician Assistants
Reallocation of healthcare is one solution to the problems healthcare is facing. In the Netherlands reallocation of care to Physician Assistants (PAs) hasn't adequately been studied.
- Trial name
- NCT01835444
- Testing
- PA/MD model
- Where
- 24 sites in Netherlands
- Volunteers
- 2,382 people
- Sponsor
- Radboud University Medical Center
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Patient Experiences of Multiple Sclerosis (PExMS)
Besides coping with the diagnosis, people with multiple sclerosis have to make complex decisions such as deciding about immunotherapies.
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Patient Engagement, Self Efficacy
- Trial name
- PExMS (NCT04236544)
- Testing
- PExMS and DECIMS-Wiki, DECIMS-Wiki
- Volunteers
- 55 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetes Mellitus, Telemedicine
Community- and mHealth-Based Integrated Management of Diabetes in Primary Healthcare in Rwanda
The Home Based Care Practitioners (HBCPs) programme has been established by the Rwandan Ministry of Health in response to the shortage of health professionals.
- Conditions
- Diabetes Mellitus, Telemedicine, Community Health Workers
- Trial name
- D²Rwanda (NCT03376607)
- Testing
- HBCP programme, mobile health application
- Where
- 9 sites in Rwanda
- Volunteers
- 209 people
- Sponsor
- University of Aarhus
Delivery of Health Care
Financial Incentives for Care Gaps
This project seeks to understand how individuals respond to financial incentive programs for wellness care. In a randomized controlled trial among customers with care gaps, the investigators will experimentally compare the…
- Trial name
- NCT03715907
- Testing
- Financial Incentives, Information
- Where
- United States
- Volunteers
- 8,042 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Influenza
Project IMPACT Immunizations (IMProving America's Communities Together)
The primary objective of this study is to evaluate how implementing an innovative care model that provides the pharmacist access to a patient's vaccine history at the point-of-care impacts the pharmacist's ability to identify…
- Trial name
- NCT02584036
- Testing
- Vaccine administration by a pharmacist, Unmet vaccination needs identified and met, Vaccination forecast review and patient education
- Where
- 8 sites in United States
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- American Pharmacists Association Foundation
Edentulous Mouth, Edentulous Jaw
Canine Guidance vs Bilateral Balanced Occlusion in Complete Denture
The objective of this study is to compare the canine guidance (CG) and bilateral balanced occlusion (BBO) on denture satisfaction and kinesiographic parameters of complete denture wearers, by means of a cross-over trial.
- Trial name
- NCT01420536
- Testing
- Occlusal scheme
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Preterm Birth Complication, Preterm Birth
Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities
The goal of this clinical trial is to learn if a personalized prenatal support program [(Personalized Toolkit Building a Comprehensive Approach to Resource optimization and Empowerment in Pregnancy \& Beyond, (PTBCARE+)] works to…
- Conditions
- Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia
- Trial name
- PTBCARE+ (NCT06915428)
- Testing
- Care coordination, Electronic massage, support gift #1
- Where
- United States
- Volunteers
- 1,228 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes Mellitus, Type 2
Project Dulce for Arab Americans With Type 2 Diabetes
Arab Americans (AA) face many challenges in diabetes self-management due to the limited educational resources and support available for them.
- Trial name
- NCT05580536
- Testing
- Project Dulce + Dulce Digital
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Scripps Whittier Diabetes Institute
HIV-1-infection
Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa
This is a prospective observational cohort study enrolling participants in South Africa and Uganda who are prescribed an HIV treatment regimen containing lamivudine, tenofovir, and dolutegravir, which is known as TLD.
- Trial name
- DISCO (NCT04066036)
- Testing
- This is an observational study only.
- Where
- 2 sites in South Africa, Uganda
- Volunteers
- 999 people
- Sponsor
- Massachusetts General Hospital
Primary Health Care Providers, Early Childhood Behavior
Young Children and Screens: Parents' Perspectives and Child Health Nurses' Approaches in a Digital Age
The overall aim of the research project is to investigate screen habits among children (0-5 years) and their parents including nurses' perspective, and further parents' and nurses' experiences of using web-based healthcare…
- Conditions
- Primary Health Care Providers, Early Childhood Behavior, Child Health Services, Parenting Practices
- Trial name
- NCT07168057
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska Institutet
Type 2 Diabetes, Hypertension
Step Monitoring to Improve ARTERial Health
Many people with diabetes and/or high blood pressure (hypertension) are not very active. When people are more active, they can reduce the chances of having a heart attack or stroke.
- Trial name
- SMARTER (NCT01475201)
- Testing
- Step count prescription, Usual care
- Where
- 6 sites in Canada
- Volunteers
- 347 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Covid19
OD-doxy-PNV-COVID-19 Old Drug " DOXY " for Prevention of New Virus " COVID-19 "
Given the urgency of having guidelines for the management of COVID-19 in the current epidemic context and the lack of specific pharmacological treatment, Military Health recommends the launch of a multicenter, randomized…
- Trial name
- NCT04584567
- Testing
- Doxycyclin
- Where
- Tunisia
- Volunteers
- 194 people
- Sponsor
- Hedi Gharsallah
Delivery of Health Care, Health Services
The COPACC Study: Utilization, Health and Economic Evaluation of a Community-Based Primary Care Geriatric Hub at Whampoa
This study evaluates the Community for Successful Ageing (ComSA) Patient-Centered Medical Home (PCMH), a model of community-based primary care geriatric hub at Whampoa, Singapore.
- Conditions
- Delivery of Health Care, Health Services, Costs and Cost Analysis, Quality of Life
- Trial name
- NCT04594967
- Testing
- Patient-centred care home (PCMH)
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Geriatric Education and Research Institute
A Multilevel, Tailored COVID-19 Testing Condition, A Nontailored COVID-19 Testing Control Condition
A Faithful Response to COVID-19 Project
This 2-arm clustered, randomized community trial will test a multilevel, COVID-19 testing and linkage to care (eg, health insurance, medical appointments, community resources, contact tracing) intervention against a nontailored…
- Trial name
- FR (NCT04978207)
- Testing
- A Faithful Response to COVID-19
- Where
- 10 sites in United States
- Volunteers
- 1,013 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Immunologic Activity Alteration
Asymptomatic COVID-19 Infection Among Healthcare Workers
To assess the seroprevalence of SARS-CoV-2 IgG in Health care workers in three University Hospitals
- Trial name
- NCT04354792
- Testing
- Serum SARs COV 2 IGg screening in health care workers
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Burn Out, Nurses
Mitigating Burnout in Nursing and Associated Healthcare Staff
Workplace stress for healthcare workers is at an all-time high and the COVID-19 Pandemic magnified and amplified the impact of stress and burnout on health care workers, especially for frontline staff such as nurses.
- Trial name
- NCT07018609
- Testing
- Zen Den Experience, Music Therapy Experience
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Ulcerative Colitis
Methods of Improvement Adherence With Therapy in Ulcerative Colitis.
Ulcerative Colitis is associated with a significantly increased risk of colorectal cancer. This risk can be reduced through regular medication with 5ASA compounds.
- Trial name
- NCT00398593
- Testing
- Range of electronic pill dispensers with alarms
- Volunteers
- 80 people
- Sponsor
- University Hospitals, Leicester
Communication, Patient Care
Development and Validation of a Tool to Measure Hand-off Quality
The aim of this project is to develop and validate a simple, flexible, reliable, real-time observation tool to evaluate hand-off practices.
- Conditions
- Communication, Patient Care, Quality of Health Care
- Trial name
- NCT01059942
- Testing
- mock handoff exposure, Introduction of CEX tool in Actual Hand-offs
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Chicago
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