Clinical trials: Health Care Delivery
Multiple Myeloma or Amyloidosis
Prospective Evaluation of Subcutaneous Administration of Daratumumab by the FreedomEDGE® Infusion System
This study is evaluating a new method for administering daratumumab, a treatment commonly used in the management of multiple myeloma and amyloidosis.
- Trial name
- ESCAPE (NCT07721350)
- Testing
- Subcutaneous Daratumumab Administration Using FreedomEDGE®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Tobacco Use, Tobacco Use Cessation
Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation
This develops a novel behavioral tobacco cessation program for pregnant smokers in San Bernardino County.
- Conditions
- Tobacco Use, Tobacco Use Cessation, Tobacco Use in Childbirth
- Trial name
- SFHOPE (NCT06438549)
- Testing
- HCP-CHW Integration into Prenatal Care for Smoking Cessation, Control Arm
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Loma Linda University
Chronic Physical Health Conditions
Therapist-Guided Internet-Delivered CBT for Chronic Conditions: Predictors of Change
Chronic health conditions are common, disabling, and often co-occur with depression and anxiety. Internet-delivered cognitive behaviour therapy (ICBT) reduces barriers to treatment and has been adapted for chronic conditions.
- Trial name
- NCT07233980
- Testing
- Internet-delivered CBT - Chronic Conditions Course (CCC)
- Where
- 2 sites in Canada
- Volunteers
- 260 people
- Sponsor
- University of Regina
Patient Engagement, Patient Activation
At-home Breast Oncology Care Delivered With E-health Solutions
The COVID-19 pandemic has significantly impacted healthcare service delivery, highlighting the need for high quality virtual patient care.
- Conditions
- Patient Engagement, Patient Activation, Patient Reported Outcome Measures
- Trial name
- ABODE (NCT05989477)
- Testing
- At-home Breast Oncology care Delivered with E-health solutions - ABODE
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Hypertension; Community Health Workers
Effectiveness of a Community Health Worker Delivered Care Intervention for Hypertension Control in Uganda
Over 80% of the morbidity and mortality related to non-communicable diseases (NCDs) occurs in low-income and middle-income countries (LMICs).
- Trial name
- CHW-HTC (NCT05068505)
- Testing
- Community health worker delivered multicomponent intervention
- Where
- Uganda
- Volunteers
- 869 people
- Sponsor
- Charite University, Berlin, Germany
Infectious Disease, Cardiovascular Disease
Promoting Evidence-Based Decision-Making in India: District Evaluation Study on Health
The purpose of this study is to assess the impact of disseminating information on comparative performance, along with actionable messages on how to improve health outcomes, to district-level decision-makers in India using a…
- Trial name
- DESH (NCT01003587)
- Testing
- District health information package
- Where
- 2 sites in Canada, India
- Volunteers
- 594 people
- Sponsor
- Unity Health Toronto
Diabetes Type 2
Changing the Healthcare Delivery Model
This is a randomized controlled trial comparing 3 strategies to improve wellness behaviors and clinical goals for diabetes type 2(DM2) Medicaid patients.
- Trial name
- C4H (NCT02093234)
- Testing
- mobile health care application, CHWs and mobile health care application, Community Health Worker (CHW)
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- George Washington University
Parkinson Disease
"Parkinson AKTIV - Non-pharmacological Treatments in an Innovative Parkinson's Network"
The purpose of this study is to evaluate the efficacy of an online platform that allows neurologists and therapists to exchange therapy recommendations, communicate assessments and plan physical therapy, occupational therapy as…
- Trial name
- ParkinsonAKTIV (NCT05251298)
- Testing
- Coordination through the online platform "JamesAKTIV"
- Where
- Germany
- Volunteers
- 370 people
- Sponsor
- University Hospital Muenster
Cancer
Simplifying Survivorship Care Planning
OBJECTIVE: The purpose of this study is to identify an SCP process that is patient-centered, effective in promoting appropriate survivorship care and can be successfully implemented for patients with different types of cancer who…
- Trial name
- SSCP (NCT03035773)
- Testing
- Care Plan Only, Care Plan During a Visit, Care Plan During a Visit with an Additional Visit
- Where
- 2 sites in United States
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Oral Health, Dental Care
Oral Health Recovery Group
The aim of the study is to test a brief, peer-led group-based oral health educational intervention - called the "Oral Health Recovery Group" - designed for individuals with psychiatric disabilities.
- Conditions
- Oral Health, Dental Care, Psychiatric Diagnosis
- Trial name
- NCT05864027
- Testing
- Peer-led Oral Health Recovery Group, Educational Video about Oral Health
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- University of Michigan
Antenatal Care and Delivery
Health Care Intervention Research- Improving Pre-natal and Maternal Care
Besides a dramatic lack of financial and human resources in developing countries, health care is additionally endangered by quality deficiencies caused by low staff motivation.
- Trial name
- QUALMAT (NCT01409824)
- Testing
- CDSS
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Heidelberg University
Primary Prevention
Increasing the Effect of a School-based Prevention Program by Teacher Involvement
Cluster-Randomized Clinical trial, which includes the development and activation of an intervention program among young adolescents and their teachers.
- Trial name
- NCT04682613
- Testing
- Experimental: Prevention Program "young In Favor of Myself", active teachers, Experimental: Prevention Program "young In Favor of Myself", no teacher involvement
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Anxiety Disorder
Strongest Families (Formerly Family Help Program): Pediatric Anxiety
The purpose of the Strongest Families (formerly Family Help Program)is to evaluate the effectiveness of the Strongest Families distance intervention compared to usual or standard care that is typically provided to children with…
- Trial name
- FHP-ANX (NCT00267566)
- Testing
- Strongest Families (formerly Family Help Program): Anxiety Program
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Volume Delivery
Sayana-Uniject Volumetric Delivery
The purpose of this study is to determine the volumetric delivery of the Uniject.
- Trial name
- NCT01298479
- Testing
- Uniject
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Substance-Related Disorders, Mental Disorder
Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa
Poor engagement in care contributes to HIV- and TB-related morbidity and mortality in South Africa (SA). Community health workers (CHWs) are frontline lay health workers who work to re-engage patients who are lost to follow-up…
- Conditions
- Substance-Related Disorders, Mental Disorder, Social Stigma, Depression
- Trial name
- Siyakhana (NCT05282173)
- Testing
- Siyakhana CHW Training
- Where
- South Africa
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Health Care Delivery, Telephone Hotlines
Degree of Worry as a Predictor for Utilization of Acute Health Care
The overall aim of the study is to construct a scale that systematically incorporates the callers' perspective in a "degree of worry - scale" and to explore the consequences for the actors in the system - caller, call-handler…
- Conditions
- Health Care Delivery, Telephone Hotlines, Patient Participation
- Trial name
- NCT02979457
- Testing
- Awareness of degree of worry
- Where
- Denmark
- Volunteers
- 11,340 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Chronic Pain
Implementation and Evaluation of a Stepped-Care Mental Health Treatment Program for Patients With Chronic Pain
Chronic pain affects nearly 20% of Canadians, and sixty percent or more of individuals with chronic pain are also struggling with mental health or substance use disorders (referred to as complex chronic pain, or CCP, patients).
- Trial name
- NCT04885192
- Testing
- Stepped-Care Model
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Opioid Use Disorder (OUD), Addictology
Autonomous Methadone Delivery System by Nurses
Initiations of methadone treatment for opiode use disorder (OUD) are carried out in France in specialized centers, known as centers for care, support and prevention in addictology (CSAPA) In this way, hospital practitioners…
- Trial name
- DIADEME (NCT07085377)
- Testing
- DIADEME strategy, Controle strategy, Individual semi directive interview
- Where
- 8 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospices Civils de Lyon
Contraception
The Share Health Study: Teen Social Connections and Health
The purpose of this study is to determine whether delivery of SpeakOut, a behavioral intervention to increase social communication about long-acting reversible contraceptive (LARC) methods among adolescents, is associated with…
- Trial name
- NCT02791971
- Testing
- SpeakOut, Alcohol Control Intervention
- Where
- 2 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Maternal Nutritional Deficiency During Childbirth
cRCT to Improve Maternal Nutrition Service Delivery During ANC
Malnutrition among women of reproductive age is a significant public health problem in Bangladesh, with major implications for a woman's own health and that of her newborn child.
- Trial name
- NCT04559711
- Testing
- Strengthening coverage and quality of nutrition services during ANC
- Where
- Bangladesh
- Volunteers
- 2,520 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh