Clinical trials: Health Equity
Vaccines
The Next Generation Vaccine Card: Innovative Technology to Improve Vaccine Equity in Rural and Urban Settings in East Africa
The research team of investigators from University of Michigan and the African Population and Health Research Center will implement and evaluate a newly-developed digital vaccine card and accompanying mobile application and…
- Trial name
- NCT06470919
- Testing
- SMS reminders for upcoming vaccination(s)
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 3,522 people
- Sponsor
- University of Michigan
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Improving Prison Health Equity Through Cancer Literacy and Screening Awareness in Florida
This study evaluates cancer screening awareness, personal and family cancer history, and barriers to screening among incarcerated women at Gadsden Correctional Facility.
- Trial name
- NCT07215039
- Testing
- Survey
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lung Cancer, Smoking Behaviors
Health Opportunities and Promoters of Equitable Screening for Lung Cancer
The goal of this clinical trial is to promote lung cancer screening (LCS) uptake among Hispanic current and former smokers. The main questions it aims to answer are: What barriers do current and former Hispanic smokers face in…
- Conditions
- Lung Cancer, Smoking Behaviors, Diagnosis
- Trial name
- HOPES (NCT05784922)
- Testing
- Educational Lung Cancer Screening (LCS) Video
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Massachusetts General Hospital
Hypertension
Precision Nudging for Hypertension Management: Observational Study
The purpose of the proposed observational study is to explore the relations between data-driven personalization and equitable health outcomes in a digital health intervention (DHI) for hypertension management.
- Trial name
- NCT06354192
- Testing
- Precision Nudging for Hypertension Management
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Lirio
Parkinson Disease
Parkinson's Research With Inclusion, Diversity and Equity
The purpose of this study is to identify the health and healthcare needs of LGBTQIA+ and non LGBTQIA+ communities living with Parkinson's disease.
- Trial name
- PRIDE (NCT05556993)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Breastfeeding
The Impact of Telelactation Services on Breastfeeding Outcomes
This project will assess the impact of a novel breastfeeding support intervention ("telelactation"), delivered via video calls on personal devices including mobile phones and tablets.
- Trial name
- NCT04856163
- Testing
- Telelactation support
- Where
- United States
- Volunteers
- 2,108 people, healthy volunteers welcome
- Sponsor
- RAND
Mental Health
Study of Mental Health and Relationships
The goal of this clinical trial is to test effects of the Great Life Mentoring (GLM) program on the mental health and adaptive functioning on school-age youth (ages 9-16) from low-income families who are receiving outpatient…
- Trial name
- SMART (NCT06534827)
- Testing
- Great Life Mentoring
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Gender Equity
Chamas for Change: Impact of the COVID-19 Pandemic
In Kenya, the chamas strategy (a peer support approach aimed at improving MNCH and reducing gender and social inequalities) has been shown to significantly improve maternal and child health outcomes while also providing social…
- Trial name
- NCT05787392
- Testing
- Chamas cha MamaToto program
- Where
- 2 sites in Kenya
- Volunteers
- 444 people
- Sponsor
- Moi University
Chronic Pain, Depression
Equity Using Interventions for Pain and Depression - Pilot Study
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This pilot randomized controlled trial (RCT) is part of phase 1 of a two-phase, 5-year project with the overarching…
- Conditions
- Chronic Pain, Depression, Health Equity
- Trial name
- EQUIPD-Pilot (NCT05695209)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Interventions to Enhance Emergency Health Care
EQUIP Emergency: Promoting Health Equity for Indigenous and Non-Indigenous People in Emergency Departments
Emergency Departments (EDs) in Canada often operate over-capacity and are under significant pressures. In this environment, particular groups of people experience inadequate and inequitable treatment in EDs, including Indigenous…
- Trial name
- NCT03369678
- Where
- 3 sites in Canada
- Volunteers
- 5,439 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women With Early-Stage Breast Cancer
This clinical trial evaluates if in-person acupuncture or virtual acupressure therapy prevents aromatase inhibitor-associated joint pain in Non-Hispanic Black postmenopausal women with stage I-III (early-stage) hormone receptor…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma
- Trial name
- NCT06534125
- Testing
- Acupressure Therapy, Acupuncture Therapy, Aromatase Inhibition Therapy
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Cardiovascular (CV) Risk, Metabolic Health
Advancing Health Equity and Preventive Cardiovascular Care in Indigenous and Remote Communities: a Mobile Healthcare Unit
Indigenous people living in Canada face significant healthcare inequities, particularly in basic, primary, and secondary prevention, leading to higher rates of cardiovascular disease and mortality.
- Conditions
- Cardiovascular (CV) Risk, Metabolic Health, Primary Prevention
- Trial name
- NCT07869069
- Testing
- Cardiovascular risk screening, Follow-up of cardiovascular risk factors
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Laval University
Maternal Mortality Disparities, Maternal Morbidity Disparities
Scaling up Maternal Health Equity Best Practices
This study works with prenatal and postnatal care providers in 12 Michigan counties to scale up best practices for maternal health equity.
- Trial name
- NCT06541951
- Testing
- Services as usual, Scale-up implementation approach
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Aortic Valve Stenosis, Mitral Regurgitation
Addressing Under-treatment and Health Equity in AS and MR Using an Integrated EHR Platform
This multi-center, prospective, cluster-randomized controlled trial will evaluate Tempus Next automated notifications as an intervention to support identification and evaluation of patients possibly indicated for Valve…
- Trial name
- ALERT (NCT06099665)
- Testing
- Automated alert
- Where
- 6 sites in United States
- Volunteers
- 2,118 people
- Sponsor
- Tempus AI
Breast Cancer, Lung Cancer
Accountability for Cancer Care Through Undoing Racism and Equity
Purpose: African American cancer patients, as compared to their White counterparts, continue to initiate treatment later and remain less apt to undergo complete treatment; fueling worse treatment outcomes including shorter…
- Trial name
- ACCURE (NCT01954641)
- Testing
- ACCURE Navigator, Usual Care by Cancer Center Care Team
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Insufficient Sleep
Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults
The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behaviors among African Americans (AAs), given the high disease burdens associated with low physical activity, insufficient…
- Trial name
- NCT06226077
- Testing
- sleep extension intervention, contact control intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Depression, Anxiety, Satisfaction
A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVID
For this project the broad research objective is to evaluate the effectiveness of an enhanced digital wellbeing program in improving well-being, depression, anxiety, stress, resilience, and job satisfaction of physicians.
- Conditions
- Depression, Anxiety, Satisfaction, Well-being
- Trial name
- Thrive (NCT05931432)
- Testing
- Comprehensive Well-Being Intervention
- Where
- United States
- Volunteers
- 293 people
- Sponsor
- University of Pennsylvania
Vaccination Refusal, Covid19
Improving Health Equity for COVID-19 Vaccination for At-risk Populations Using Online Social Networks
Social technologies for health have already become essential means for providing underserved populations greater social connectedness and increased access to novel health information.
- Conditions
- Vaccination Refusal, Covid19, Heart Diseases
- Trial name
- NCT04779827
- Testing
- Online Social Network and Collective Intelligence Intervention, Independent Control
- Where
- United States
- Volunteers
- 4,476 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chronic Disease Prevention
Engaging Partners in Caring Communities
The goal of the EPICC observational study is to learn about capacity to implement evidence-based health promotion programs (EBPs) in congregations that are offered semi-structured technical assistance (TA).
- Trial name
- EPICC (NCT06932549)
- Testing
- Technical assistance is designed to integrate Expert Recommendations for Implementing Change (ERIC) strategies, and Getting To Outcomes-TA.
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tennessee State University
Tobacco Use Disorder, Tobacco Dependence
Equitable Smoking Relapse Prevention
The goal of this clinical trial is to test a GPS (Global Positioning System)-enabled smartphone app (QuitBuddy) in current smokers.
- Trial name
- NCT05625685
- Testing
- Quitbuddy, Control, SDoH Augmentation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bryan W. Heckman