Clinical trials: Health Maintenance
Smoking Cessation
A 52-Week Multicenter Study Evaluating the Safety and Efficacy of Varenicline for the Maintenance of Smoking Cessation
The primary purpose of this study is a comparison of abstinence maintenance in subjects randomized to double-blind varenicline or placebo from Weeks 13 -24 in subjects who responded to an intial 12-week open label course of…
- Trial name
- NCT00143286
- Testing
- varenicline (CP-526,555)
- Where
- 24 sites in United States, Canada and 5 more
- Volunteers
- 2,000 people
- Sponsor
- Pfizer
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Pulmonary Disease, Chronic Obstructive
Safety of Tiotropium + Olodaterol in Chronic Obstructive Pulmonary Disease (COPD) Patients in Taiwan: a Non-interventional Study Based on the Taiwan National Health Insurance (NHI) Data
The aim of this real world study is to assess the safety profile of tiotropium/olodaterol (Tio/Olo).
- Trial name
- NCT05393245
- Testing
- Tiotropium+Olodaterol, Spiolto Respimat, Long-acting muscarinic antagonists (LAMAs)
- Where
- China
- Volunteers
- 19,467 people
- Sponsor
- Boehringer Ingelheim
Cold Symptoms
Efficacy and Safety of Imuneks 10 mg Capsules in the Prophylaxis of Cold
The objective of this study is to evaluate the efficacy and safety of Imuneks 10 mg Capsules in the prophylaxis of cold and the maintenance of the good health state in 70 healthy subjects.
- Trial name
- NCT02807220
- Testing
- Imuneks 10mg
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imuneks Farma ilac San. Tic. A.S.
Crohn's Disease
Efficacy of CROWN in Repair and Maintenance of the Intestinal Mucosa in Patients With CD Receiving Anti-TNF Therapy
The purpose of this study is to evaluate CROWN's efficacy in supporting the repair and maintenance of the intestinal mucosa of patients with moderately to severely active Crohn's Disease receiving anti-Tumor Necrosis Factor (TNF)…
- Trial name
- PIONEER-CD (NCT02793778)
- Testing
- CROWN
- Where
- 39 sites in United States
- Volunteers
- 42 people
- Sponsor
- Prometheus Laboratories
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Poor Sleep Quality, Gut Microbiome
The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) use affects gut microbiome composition, inflammation, and the body's daily temperature and blood pressure…
- Conditions
- Poor Sleep Quality, Gut Microbiome, Gut Health, Inflammation
- Trial name
- NCT07848594
- Testing
- Overnight Active Temperature Regulation: Eight Sleep Pod System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eight Sleep Inc.
Depression, Insomnia
PracticeGround: Transforming Training and Delivery of Mental Health EBPs
The ultimate goal is to facilitate the delivery of empirically supported treatments (ESTs) for mental disorders and to improve client mental health outcomes.
- Conditions
- Depression, Insomnia, Suicide
- Trial name
- NCT02314624
- Testing
- Behavioral Activation for Depression, Cognitive Behavior Therapy for Insomnia, Collaborative Assessment and Management of Suicidality, Care-as-Usual Psychotherapy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Insomnia Disorder
Effectiveness of a Digital Health Application for People With Insomnia Disorder (Somnovia)
The trial aims to evaluate the effectiveness of a novel digital health application (somnovia), which was designed to increase sleep quality in persons with insomnia disorder.
- Trial name
- NCT05558865
- Testing
- somnovia
- Where
- Germany
- Volunteers
- 290 people
- Sponsor
- Gaia AG
Pulmonary Disease, Chronic Obstructive
A Study in the US Based on Pharmacy and Medical Claims That Compares How Well Stiolto® and Trelegy® Work in People With Chronic Obstructive Pulmonary Disease (COPD)
This study looks at data from people with chronic obstructive pulmonary disease (COPD). Some used Stiolto Respimat and the others Trelegy Ellipta as their first treatment for COPD.
- Trial name
- NCT05169424
- Testing
- Trelegy Ellipta, Stiolto Respimat, Tiotropium + Olodaterol (5/5 mcg)
- Where
- United States
- Volunteers
- 9,117 people
- Sponsor
- Boehringer Ingelheim
Sleep Disturbance
Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints
This open-label study was designed to evaluate whether a daily dietary sleep supplement could improve sleep quality and related daytime well-being in menopausal women aged 40 to 65 with sleep complaints.
- Trial name
- NCT07839312
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Menopause Related Conditions
ProGo Menopause Wellbeing Study
This study will evaluate whether ProGo®, a salmon protein hydrolysate (SPH), helps to moderate body mass index (BMI) and improve quality of life (QoL) in menopausal women.
- Trial name
- NCT07611305
- Testing
- Salmon protein hydrolysate (SPH) powder formulated into a tablet format, Microcrystalline Cellulose
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Sleep Disturbances
Bonafide Sleep Supplement for Menopausal Women With Impaired Sleep
This open-label study evaluated whether a daily dietary sleep supplement could improve sleep and related daytime functioning in menopausal women aged 40 to 65 with impaired sleep.
- Trial name
- NCT07839299
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bonafide Health