Clinical trials: Health Prevention
Obesity, Sedentary Lifestyle
The Healthy Options Feasibility Study
The investigators hypothesize that having health care providers other than physicians within a "Groupe de Médecine de Famille" conduct cardiovascular risk assessments and teach lifestyle interventions to primary prevention…
- Conditions
- Obesity, Sedentary Lifestyle, Dyslipidemia, Hypertension
- Trial name
- NCT00746460
- Testing
- CVD risk profile
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University
Hypertension (HTN), Vascular Diseases
The BASIC-S Feasibility Study for Vascular Risk Reduction
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging.
- Conditions
- Hypertension (HTN), Vascular Diseases, Stroke, Dementia
- Trial name
- BASIC-S (NCT07755631)
- Testing
- BASIC-S Intervention, Standard / Usual Care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Andrew Appleton
Obesity, Activity, Motor
Efficacy Trial of Healthy Together ("Juntos")
The purpose of this study is to assess the efficacy of a family-based digital (web and mobile phone-based) program known as Healthy Together ("Juntos") in preventing increases in body mass index and improving moderate-to-vigorous…
- Conditions
- Obesity, Activity, Motor, Diet, Healthy
- Trial name
- NCT06489262
- Testing
- Healthy Together ("Juntos")
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Miami
Depression, Men
The Effects of E-mental Health Program and Job Coaching on the Risk of Major Depression in Canadian Working Men
There is a pressing need for innovation in prevention of major depression in male workers. Major depression (MDE) affects workers' health and productivity.
- Trial name
- NCT02777112
- Testing
- e-mental health program, e-mental health program and job coaching, No intervention
- Where
- Canada
- Volunteers
- 1,133 people
- Sponsor
- University of Calgary
Suicide Prevention, Suicidal Ideation
Co-creation of Tools for Men With Suicidal Thoughts and/or Behavior
The primary objective of this project is to co-create suicide prevention tools for men with suicidal thoughts ensuring these tools are supported by their future users.
- Conditions
- Suicide Prevention, Suicidal Ideation, Suicidal Behaviour
- Trial name
- NCT06629220
- Testing
- Tools
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- University Ghent
Depression
Primary Prevention of Major Depression Based on the Level and Profile of Risk of Primary Care Attenders: Cluster, Controlled, Randomised Trial
The main objective is to measure the effectiveness of a new intervention for primary prevention of major depression based on the level and profile of risk of primary care attendees.
- Trial name
- predictD-CCRT (NCT01151982)
- Testing
- Psychosocial Intervention
- Where
- 2 sites in Spain
- Volunteers
- 3,326 people
- Sponsor
- The Mediterranean Institute for the Advance of Biotechnology and Health Research
Obesity, Obesity, Childhood
In-home Obesity Prevention to Reach Low-income Infants
Existing obesity prevention efforts have had limited success among underserved, low-income children. This study capitalizes on the strengths of a nationwide ongoing Home Visitation Program (HVP), which serves at-risk, low-income…
- Conditions
- Obesity, Obesity, Childhood, Obesity; Familial
- Trial name
- NCT03529695
- Testing
- Standard HVP Curriculum, Obesity Prevention
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Drug Adherence
Patient Autonomy and Statin Therapy Adherence
The rationale for the Patient Autonomy and Statin Therapy Adherence (PASTA) trial is based on the fact that statin therapy is a highly effective and evidence-based treatment for reducing the risk of cardiovascular disease.
- Trial name
- PASTA (NCT05845580)
- Testing
- Red yeast rice extract initial therapy followed later on by statin therapy, Statin therapy
- Where
- Lithuania
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Overweight and Obesity, Social Determinants of Health
The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early Life
The First 1000 Days (conception to age 2) is a crucial period for the development and prevention of obesity and its adverse consequences in mother-child pairs and their families.
- Conditions
- Overweight and Obesity, Social Determinants of Health, Physical Activity, Sleep
- Trial name
- NCT03191591
- Testing
- First 1,000 Days Program Site
- Volunteers
- 1,645 people
- Sponsor
- Massachusetts General Hospital
Basal Cell Carcinoma
Basal Cell Carcinoma Chemoprevention Trial
This is an intent-to-treat, parallel design, multicenter randomized trial and the primary intervention is a double-blind comparison of imiquimod (IMQ) vs.
- Trial name
- B3C (NCT05212246)
- Testing
- 5% Imiquimod cream
- Where
- 8 sites in United States
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases (CVD)
Healthy Living With Online suPport & Education for Cardiovascular Disease in the Primary Care Setting
This pragmatic four-arm (1:1:1:1) parallel cluster randomised controlled trial (cRCT) aims to evaluate the effectiveness of reducing the risk of cardiovascular disease (CVD) through three combinations of interventions for…
- Trial name
- HOPE-CVD-GP (NCT06099353)
- Testing
- Heart Age, Heart Age-HOPE-CVD App, Communication of Genetic Risk Score
- Where
- Singapore
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Household Air Polution, Cardiovascular Diseases
GEOHealth Hub: Household Air Pollution and Cardio-pulmonary and Immune Function Outcomes
Background: The increasing effect of environmental, occupational and climate change poses serious global threat for public health.
- Conditions
- Household Air Polution, Cardiovascular Diseases, Lung Diseases, Immune Dysfunction
- Trial name
- NCT02824237
- Testing
- Improved cook stove
- Where
- Bangladesh
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Job Satisfaction, Work Performance
Life Skills Training Workplace Prevention Program
A workplace health promotion intervention for youth age 16-24
- Conditions
- Job Satisfaction, Work Performance, Health Care Utilization, Depression Symptoms
- Trial name
- LST-WP (NCT06745739)
- Testing
- Life Skills Training Workplace Prevention Program
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Hiv, Transmission Vertical
Differentiated Service Delivery for Pregnant and Postpartum Women Living With HIV and Their Infants
Differentiated service delivery (DSD) is an evidence-based HIV care and treatment model endorsed by the World Health Organization (WHO) that simplifies HIV services for clients who are clinically stable, improving the quality and…
- Conditions
- Hiv, Transmission Vertical, Viremia, Health Care Acceptability
- Trial name
- NCT06629753
- Testing
- Differentiated service delivery model
- Where
- Kenya
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Indiana University
Vaginal Delivery, Pelvic Organ Prolapse
EASE: The Materna Prep Pivotal Study
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery.
- Trial name
- NCT03973281
- Testing
- Materna Prep Device, Standard of Care (SOC)
- Where
- 22 sites in United States
- Volunteers
- 420 people
- Sponsor
- Materna Medical
Body Image Disturbance, Disordered Eating Behaviors
Adolescent Chatbot
The purpose of this study is to test an eating disorders prevention digital chatbot program in a diverse group of adolescents.
- Conditions
- Body Image Disturbance, Disordered Eating Behaviors, Eating Disorder Prevention
- Trial name
- EMBody (NCT07094503)
- Testing
- Wysa Digital Chatbot Program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Washington University School of Medicine
HIV Infections
Computerized Counseling to Promote Positive Prevention and HIV Health in Kenya
The purpose of this study is to see if a computerized counseling tool helps patients reduce their sexual transmission risk and improve their antiretroviral adherence.
- Trial name
- CARE+ Kenya (NCT01015989)
- Testing
- CARE+ Kenya brief computer risk assessment session, CARE+ Kenya computer counseling session
- Where
- 2 sites in Kenya
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- New York University
Prevention
Integrated Behavioral Health Prevention in Pediatric Primary Care for Infants
The purpose of the study is to evaluate the acceptability and preliminary efficacy of a universal prevention program delivered by psychologists in conjunction with pediatric primary care well-child visits.
- Trial name
- NCT04825210
- Testing
- Integrated Behavioral Health - Prevention, Bright Futures: Guidelines for Health Supervision of Infants, Children, and Adolescents, 4th Edition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Type 2 Diabetes Mellitus
Evaluation of the Educational Program of Diabetes Mellitus: Focus on Empowerment
With health education, patients will have knowledge of the disease and may modify their attitudes to diabetes. Have a different behavior, will perform self-management of their health.
- Trial name
- NCT02132338
- Testing
- The Education Health Program
- Where
- Brazil
- Volunteers
- 191 people
- Sponsor
- Federal University of Minas Gerais
Bacterial Vaginosis
Photobiomodulation With Blue LED in Recurrent Bacterial Vaginosis
Introduction: Bacterial vaginosis (BV) is the most prevalent vaginal dysbiosis in women of reproductive age and is associated with adverse gynecological and obstetric outcomes; therefore, its diagnosis and appropriate treatment…
- Trial name
- NCT07835815
- Testing
- Metronidazole, Blue Light-Emitting Diode (LED)
- Volunteers
- 40 people
- Sponsor
- Patricia Lordelo
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