Clinical trials: Health Prevention
Unspecified Adult Solid Tumor, Protocol Specific
Internet-Based Nutrition Education Program in Preventing Cancer in Participants of Health Maintenance Organizations
RATIONALE: Websites for nutrition education may be an effective method to help people eat more fruits and vegetables which may lower their risk of cancer.
- Trial name
- NCT00169312
- Testing
- behavioral dietary intervention, dietary intervention, educational intervention
- Where
- 4 sites in United States
- Volunteers
- 2,619 people, healthy volunteers welcome
- Sponsor
- Josephine Ford Cancer Center
Health Services Accessibility
ActionHealthNYC Research Study
The ActionHealthNYC program is a year-long demonstration program to improve access to high quality health care for NYC resident immigrants who do not qualify for public insurance with incomes at or below 200% of the Federal…
- Trial name
- NCT02841930
- Testing
- ActionHealth NYC
- Where
- United States
- Volunteers
- 2,428 people, healthy volunteers welcome
- Sponsor
- New York City Department of Health and Mental Hygiene
HIV, Adherence
Evaluation of a Computer-Based System Using Cell Phones for HIV People in Peru
The investigators propose to develop and evaluate a computer-based intervention using cell phones to enhance adherence to antiretroviral treatment (ART) and support of HIV transmission risk-reduction among adult HIV-positive…
- Conditions
- HIV, Adherence, Sexual Behavior, HIV Infections
- Trial name
- Cell-POS (NCT01118767)
- Testing
- Cell phone intervention
- Where
- 2 sites in Peru
- Volunteers
- 210 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Chronic Obstructive Pulmonary Disease, Smoking Cessation
Smoking Relapse Prevention Among COPD Ex-smokers
A placebo-controlled trial to determine whether recent ex-smokers with COPD who successfully stop smoking after taking varenicline are less likely to relapse back to smoking if they continue using varenicline for a further 12…
- Trial name
- SPACE (NCT02888444)
- Testing
- Varenicline, Behavioural support
- Where
- New Zealand
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Vaping, Smoking Cessation
Vaping Prevention and Vaping in Youth (Vapechat)
Many youth are addicted to nicotine due to increased nicotine vaping (e.g., e-cigarettes). Unfortunately, there are no effective interventions to help teens quit vaping.
- Trial name
- Vapechat (NCT06003439)
- Testing
- Virtual Reality Program, VR Program
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Cardiovascular Diseases
Dietary Approaches for Cardiovascular Health Study
The primary purpose of this study is to examine the efficacy of family meal frequency as an intervention target in addressing the primary prevention of CVD.
- Trial name
- NCT05180435
- Testing
- Family Meals, Standard
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Gestational Diabetes
Mobile Instant Messaging-based Lifestyle Intervention for Gestational Diabetes Prevention
The goal of this randomised controlled trial is to test the effectiveness of a mobile instant messaging-based lifestyle intervention in pregnant women at risk of gestational diabetes
- Trial name
- NCT06061991
- Testing
- Mobile instant messaging-based lifestyle intervention, Text messaging reminders, Brief advice on GDM prevention
- Where
- 4 sites in Hong Kong
- Volunteers
- 944 people
- Sponsor
- The University of Hong Kong
Alzheimer Disease, Dementia
Reducing Dementia Risk With Digital Health Coaching
The Digital Cognitive Multi-domain Alzheimer's Risk Velocity (DC MARVEL) study is a 2-year randomized controlled trial on dementia prevention.
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment, Cognitive Decline
- Trial name
- DC-MARVEL (NCT04559789)
- Testing
- MindMate + Health Coaching, Health Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Neurotrack Technologies, Inc.
Hemophilia
Canadian CHO-KLAT/H-FIT Study - Quality of Life of, and Burden of Caring for, Persons With Hemophilia
The primary goal of this observational study is to determine if: health-related quality of life of boys with moderate/severe hemophilia A who are followed in Canadian pediatric hemophilia treatment centres is significantly…
- Trial name
- NCT06191068
- Where
- Canada
- Volunteers
- 190 people
- Sponsor
- The Hospital for Sick Children
Childhood Obesity
The Louisiana (LA) Health Project
There is a worldwide pandemic of obesity with far-reaching consequences for the health of our nation. Obesity is the second leading cause of preventable death in the United States.
- Trial name
- NCT00289315
- Testing
- Primary (Environmental) Weight Gain Prevention, Secondary (Behavioral) Weight Gain Prevention, Control
- Where
- United States
- Volunteers
- 2,060 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Nicotine Dependence, Schizophrenia
Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia
After successfully quitting smoking, smokers with schizophrenia are vulnerable to relapse shortly after discontinuation of treatment.
- Trial name
- NCT01576640
- Testing
- NRT, Bupropion SR 150mg bid, Relapse Prevention-Oriented Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Covid19
Safety and Efficacy of Intranasal Application of GX-03 as a Treatment and Prevention for COVID-19.
Phase 2b clinical trial to evaluate the safety and efficacy of intranasal application of GX-03 as a treatment and prevention for COVID-19.
- Trial name
- NCT04951349
- Testing
- GX-03, Petrolatum ointment
- Where
- 3 sites in Panama
- Volunteers
- 85 people
- Sponsor
- Turn Therapeutics
Substance Use
Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women with Trauma-related Conditions
The investigators have previously developed an integrated bio-behavioral intervention to promote PrEP uptake and adherence in cisgender women who are undergoing treatment for trauma-related mental health conditions and who are at…
- Trial name
- NCT06558825
- Testing
- Integrated Intervention to Promote PrEP Uptake, Standard Treatment Condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Liver Cirrhosis, Hepatitis B
Prevention of HCC Using Mobile Phone Applications
This prospective cohort study is initiated to evaluate the compliance improvement to the standardized follow-up and clinical management in the population of compensatory hepatitis B cirrhosis with a mobile health application…
- Trial name
- NCT05094869
- Testing
- Use of mobile health application, Online interaction, Self follow-up reminders
- Volunteers
- 8,000 people
- Sponsor
- Beijing Friendship Hospital
Diabetes Mellitus, Type 2, Family Health
Family-based Prevention of Diabetes Through Eating Habits and Physical Activity
Introduction: Type 2 diabetes represents a growing health risk for the society. An easy-access and low-cost intervention for the whole family will be developed to help families with (at risk of) type 2 diabetes maintain…
- Conditions
- Diabetes Mellitus, Type 2, Family Health, Health Behavior, Healthy Lifestyle
- Trial name
- GO_EASY (NCT05694351)
- Testing
- Healthy meals and physical activity in families with type 2 diabetes
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Slagelse Hospital
Teen Pregnancy
Evaluation of a Need to Know (N2K): A New Sex Education Program for High School Students
This trial evaluated the impact of N2K, a three-year quasi-experimental study to delay sexual initiation and increase condom and contraception use among high school students.
- Trial name
- N2K (NCT02539602)
- Testing
- The Need to Know students received the N2K curriculum as described previously
- Volunteers
- 1,616 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetes Mellitus Type 2, Obesity
Local Measures to Prevent Diabetes in the Værnes Region.
This is a development project involving four different municipalities in Central Norway. The aim is to identify adults with overweight and with an increased risk of developing diabetes mellitus type 2, then to prevent the disease…
- Trial name
- VEND-RISK (NCT01135901)
- Testing
- Behavioural change programme
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Norwegian University of Science and Technology
Pre-Eclampsia
Precision Medicine for Prediction & Prevention of Early Pre-eclampsia
This study aims to evaluate the feasibility of implementing a clinical model for precision screening of early pre-eclampsia into the current prenatal screening service at Sunnybrook Health Sciences Center (SHSC).
- Trial name
- NCT04412681
- Testing
- Enhanced PE Screening
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Eating Disorders in Adolescence, Food Addiction
Evaluation of a Digital School-Based Intervention for the Primary Prevention of Eating Disorders in Pre-Adolescents (PRETA Program)
Background: Eating Disorders (ED) are mental health conditions, characterized by pathological behaviors toward food intake or a persistent obsession with weight control.
- Trial name
- PRETA (NCT06792981)
- Testing
- Universal primary prevention program based on ICTs
- Where
- Spain
- Volunteers
- 1,068 people
- Sponsor
- Servicio Canario de Salud
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