Clinical trials: Health Prevention
HIV, Mental Health Issue
Tell Me More ("Dime Mas")
This study will be used to develop a program to help Latino men who have sex with men obtain pre-exposure prophylaxis (PrEP), HIV testing, and behavioral health services.
- Trial name
- NCT06063083
- Testing
- Tell Me More ("Dime Mas"), Peer Ambassador Stories [Listen Miami ("Oye Miami")], Standard Community Outreach
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Miami
Suicidal Ideation, Suicide Attempt
Advancing Student Suicide Interventions With Scalable Technologies
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self-Harm
- Trial name
- ASSIST (NCT07211373)
- Testing
- Jaspr, Behavioral support
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Massachusetts, Amherst
Substance Use
Adaptive Interventions for Prevention/Intervention for Youth Substance Abuse
The main aim of this formative study is to test and iteratively refine a new mobile phone app, which delivers assessments and tailored intervention content.
- Trial name
- NCT03928756
- Testing
- Push Notifications with Tailored Intervention Content, Push Notifications with Engaging, Non-therapeutic Content, No Push Notifications
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Michigan
Secondary Prevention of Coronary Heart Disease
Artificial Intelligence-Enhanced Management for Coronary Heart Disease (AIM-CHD) : Impact on Cholesterol and Other CHD Risk Factors
The goal of this clinical trial is to find out if an artificial intelligence (AI)-enhanced mobile app can help people with coronary heart disease (CHD) better manage their health after being discharged from the hospital.
- Trial name
- AIM-CHD (NCT06686056)
- Testing
- AIM-CHD Mobile Health Intervention, Usual post-discharge care
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Suicide Prevention
Suicide Prevention Study of VA-BIC in the Veteran Population
The VA is committed to reducing suicide in the U.S. Veteran population. Over 6,000 Veterans die from suicide each year, and this risk is particularly high following a psychiatric hospitalization.
- Trial name
- VA-BIC RCT (NCT04446468)
- Testing
- PEACE, Standard Psychiatric Hospital Discharge Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
HIV Infections, Stigma, Social
HIV Prevention Peer Navigation for Justice Involved Women
Women involved in the criminal justice system have complex and highly stigmatized sexual and substance use risk profiles and are particularly vulnerable to, and experience, high rates of HIV.
- Trial name
- kINSHIP (NCT04680390)
- Testing
- Standard of care engagement practices, Peer Navigators Addressing INtersectional Stigma to Improve HIV Prevention Among Criminal-Justice Involved Women
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Metabolic Syndrome
Lawrence Latino Diabetes Prevention Project
The Lawrence Latino Diabetes Prevention Project (LLDPP) is a community-based translational research study which aims to reduce the risk of diabetes among Latinos who have a >30% probability of developing diabetes in the next 7.5…
- Trial name
- LLDPP (NCT00810290)
- Testing
- lifestyle intervention
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- University of Massachusetts, Worcester
Smoking Cessation
Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Health Staff
The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 50 health staff smokers.
- Trial name
- MUSMOKHEALTH (NCT06130423)
- Testing
- Music intervention, Nicotine replacement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
HIV, Sexually Transmitted Diseases
Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic
This study will determine whether showing an educational DVD to people at sexually transmitted infection clinics can reduce incidence of new infections and risky sexual behaviors and improve overall health.
- Conditions
- HIV, Sexually Transmitted Diseases, HIV Infections
- Trial name
- NCT00947271
- Testing
- DVD 1, DVD 2
- Where
- United States
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Malaria
Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses
The general goal of the project is to assess the infectious status and immunity of mothers and children living in a malaria region.
- Trial name
- NCT00167843
- Testing
- sulfadoxine-pyrimethamine
- Where
- Gabon
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Albert Schweitzer Hospital
Periodontal Diseases, Pregnancy Complications
Oral Health and Adverse Pregnancy Complications
Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected.
- Conditions
- Periodontal Diseases, Pregnancy Complications, Pregnancy Preterm, Gestational Diabetes
- Trial name
- NCT06110143
- Testing
- Periodontal treatment
- Where
- 3 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Obesity Prevention, Pediatric Obesity
Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project
Childhood obesity is a growing public health issue affecting millions of children worldwide, increasing the risk of metabolic and cardiovascular diseases in adulthood.
- Conditions
- Obesity Prevention, Pediatric Obesity, Trisomy 21, Down Syndrome (Trisomy 21)
- Trial name
- LiverTy (NCT06888570)
- Testing
- To evaluate fat liver content in the cases/controls population.
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Major Depressive Disorder, Postpartum Depression
Maternal Mental Health Trial
Perinatal depression affects 10-15% of women postpartum and has a recurrence rate of 40%. Women who develop perinatal depression might be particularly susceptible to the rapid and large changes in sex steroid hormones…
- Trial name
- MAMA (NCT04685148)
- Testing
- Transdermal patch estradiol
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- Vibe G Frøkjær, MD, PhD
Primary Prevention
Increasing the Impact of a School Prevention Program Among Young Adolescents by Adding a Teacher Component
A randomized clinical trial in clusters, including the development and implementation of an intervention program among young adolescents and their teachers.
- Trial name
- NCT05102526
- Testing
- Experimental: "Young Millie" prevention program, active teachers, Prevention program: "Young Mili", non active teachers
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Fall Related Injury, Social Isolation
KOSO (Keep On Stepping On)/ Stepping Online
The overall purpose of this multi-phase study is to develop (Phase 1) and test potential effectiveness and feasibility of Keep On Stepping On (KOSO)/Stepping Online, an online falls prevention maintenance program for Stepping On…
- Trial name
- NCT02774889
- Testing
- Stepping Online
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
HIV Infections, Pregnancy Related
mWACh-PrEP: A SMS-based Support Intervention to Enhance PrEP Adherence During Pregnancy and Breastfeeding
In high HIV prevalence regions, women are at high risk for HIV during pregnancy and breastfeeding. To protect women and reach elimination of mother-to-child HIV transmission, the World Health Organization recommends offering oral…
- Conditions
- HIV Infections, Pregnancy Related, Adherence, Medication
- Trial name
- NCT04472884
- Testing
- mWACh-PrEP, Standard of Care
- Where
- 4 sites in Kenya
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections
Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT
The goal of this hybrid (1a) Cluster Randomised Controlled Trial phase 3B trial is to evaluate the effectiveness and implementation of offering a choice of HIV Pre-Exposure Products (PrEP) through community-based sexual and…
- Trial name
- LAPIS (NCT06250504)
- Testing
- APRETUDE (cabotegravir) 600 mg\3 mL, DAPIRING (Dapivirine) 25mg Vaginal Ring, tenofovir disoproxil and emtricitabine
- Where
- South Africa
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Burnout Syndrome, Anxiety Depression
Prevention of Burnout in Spanish Healthcare Professionals Through Attachment-Based Compassion Therapy (ABCT)
Burnout is a common problem among healthcare professionals and may affect their psychological well-being, quality of life, and professional functioning.
- Conditions
- Burnout Syndrome, Anxiety Depression, Stress
- Trial name
- NCT07698379
- Testing
- Attachment-based compassion therapy Compassion, Relaxation program
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Miguel Servet
Cervical Cancer
Comparing Health Services Interventions for the Prevention of HPV-related Cancer
The study aims to identify global and local determinants of HPV vaccine acceptability, HPV vaccine uptake and compliance as well as identify logistics and programmatic issues in each country to offer the HPV vaccine, as a…
- Trial name
- CoheaHr-WP4 (NCT02837926)
- Testing
- questionnaire, Gardasil vaccine, Cervarix®
- Where
- France
- Volunteers
- 63 people
- Sponsor
- CHU de Reims
Pregnancy (Unwanted), Sexually Transmitted Disease (STD)
#TranscendentHealth: A Text Messaging Pregnancy Prevention Program for Transgender Boys
Transgender and gender-diverse young people who were assigned female at birth (AFAB), including transgender boys, nonbinary youth, and others, face real sexual health disparities.
- Conditions
- Pregnancy (Unwanted), Sexually Transmitted Disease (STD), HIV Infection, Sexual Behavior
- Trial name
- THPP (NCT07681908)
- Testing
- #TranscendentHealth, Universal Sexual Health Program
- Where
- United States
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
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