Clinical trials: Health Prevention
Cardiovascular Diseases, Non-Alcoholic Fatty Liver Disease
Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study
Aims of the study: 1. To deliver a scalable wellbeing programme to the local population of Imperial College Healthcare NHS Trust, focusing on movement. 2.
- Conditions
- Cardiovascular Diseases, Non-Alcoholic Fatty Liver Disease, Respiratory Disease, Diabetes
- Trial name
- SWIPER-MOVES (NCT06011356)
- Testing
- Smartwatch
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Health Promotion, Tobacco Smoking
Intranet-based Tobacco Prevention Program for Children
The purpose of this research is to create an effective, disseminable, and exciting computer-based tobacco prevention program for 5th and 6th grade students.
- Trial name
- Intranet (NCT00680875)
- Testing
- Click City
- Where
- United States
- Volunteers
- 3,225 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
HIV Disease, HIV Prevention
The Unlocking PrEP Study: Integration of Peer Health Navigation Into Comprehensive Re-entry Services
This 18-month study, "Integration of peer health navigation into comprehensive re-entry services: improving PrEP implementation for justice-involved individuals," aims to increase PrEP awareness and uptake among people with a…
- Trial name
- NCT07292792
- Testing
- Health Coach Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Obesity and Type 2 Diabetes
Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents
Hispanic adolescents are disproportionately burdened by type 2 diabetes (T2D). Social determinants of health (SDoH) serve as barriers to behavior change and participation in disease prevention efforts, especially among vulnerable…
- Trial name
- Fit24+ (NCT06943001)
- Testing
- Fit24+
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Suicide Prevention
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk
The investigators are modifying and testing the preliminary effectiveness and implementation of the combination of two psychosocial interventions, Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and the…
- Trial name
- NCT06941311
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Sudan Virus Disease
A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health
A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health.
- Trial name
- NCT07565090
- Testing
- rVSVΔG-SUDV-GP
- Where
- 3 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
PreDiabetes, Overweight and Obesity
Social Determinants and a Diabetes Prevention Program Tailored for African Americans
African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income.
- Trial name
- FIT4ALL (NCT05301413)
- Testing
- Culturally Tailored Diabetes Prevention Program, Culturally Tailored DPP Enhanced with Socioeconomic Supports, Diabetes Prevention Program
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
PCOS (Polycystic Ovary Syndrome), Puberty
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
This study explores how a physical activity program can affect hormone health and diabetes risk in girls ages 8-12 who may be at higher risk.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Puberty, Insulin Resistance, Physical Activity
- Trial name
- NCT07102797
- Testing
- ActiveGirls Physical Activity Program (Full), ActiveGirls Physical Activity Program (Delayed Lower Intensity)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Contraceptive Behavior
Meaningful Use of Technology to Improve Health Care Delivery
While there have been major declines in teenage pregnancy around the country, Baltimore, Maryland has continued to experience increases over the last several years.
- Trial name
- DepoText (NCT01641380)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postpartum Anemia
Prevention of Iron Deficiency Anemia Post-delivery
PRIORITY is designed as a 2-arm, randomized-controlled trial focused on postpartum women. The trial will recruit women who are diagnosed with moderate anemia based on a blood sample taken 6-48 hours after childbirth.
- Trial name
- PRIORITY (NCT05590260)
- Testing
- Ferric carboxymaltose (FCM) and folic acid tablets, Oral iron tablets and folic acid tablets
- Where
- 8 sites in Bangladesh, Democratic Republic of the Congo and 5 more
- Volunteers
- 4,857 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
Suicidal Ideation and Behavior, Suicide
RomSi: Mobile Health Intervention to Enhance Suicide Prevention by Reducing Stigma and Increasing Literacy
Suicide is one of the leading causes of death in Spain, representing a public health crisis that requires urgent and effective solutions.
- Trial name
- NCT06759129
- Testing
- Immediate-use of a mobile health application until completion, Delayed use of a mobile health application until completion
- Where
- Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Chronic Musculoskeletal Pain, Sexual Assault
Post-traumatic Estradiol Administration and Care Evaluation (PEACE)
This pilot randomized, double-blind, placebo-controlled trial evaluates the feasibility, acceptability, and tolerability of administering a single 6 mg oral dose of 17β-estradiol (E2) to individuals assigned female at birth who…
- Conditions
- Chronic Musculoskeletal Pain, Sexual Assault, Posttraumatic Stress Disorder (PTSD)
- Trial name
- PEACE (NCT07868536)
- Testing
- 17β-estradiol
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Spinal Cord Injuries (SCI), Osteoporosis
Osteoporosis Awareness in Chronic Spinal Cord Injury
Osteoporosis is a common and serious complication of spinal cord injury (SCI), substantially increasing the risk of fragility fractures.
- Conditions
- Spinal Cord Injuries (SCI), Osteoporosis, Health Knowledge, Attitudes
- Trial name
- NCT07725081
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Afyonkarahisar Health Sciences University
Myopia, Refractive Errors
Real-World Study of Myopia Prevention and Control in Children
This prospective, school-based cohort study aims to enroll approximately 15,000 primary school students from multiple districts in Shanghai, China and to observe the outcomes on myopia prevention and control in children with…
- Conditions
- Myopia, Refractive Errors, Children, Cohort
- Trial name
- NCT06849895
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Systemic Lupus Erythematosus
HIPP Learning to Live Better With Lupus: The Health Improvement and Prevention Program in Systemic Lupus Erythematosus
Several studies have shown that persons with systemic lupus erythematosus (SLE) have poor general health and a higher risk of heart attack and bone loss (osteoporosis) compared to the general population.
- Trial name
- NCT00188357
- Testing
- Education
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- University Health Network, Toronto
Mental Health Well-being, Emotional Regulation
Feasibility of a Compassionate Mindful Resilience Programme for Thai Secondary School Students
This study is a single-arm feasibility trial designed to evaluate the implementation, acceptability, and preliminary effects of a culturally adapted Compassionate Mindful Resilience (CMR) intervention among adolescents in…
- Conditions
- Mental Health Well-being, Emotional Regulation, Psychological Resilience, Substance Use Prevention
- Trial name
- CMR-THAI (NCT07482839)
- Testing
- Four-Week Compassionate Mindful Resilience (CMR) Intervention
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Hypertension, Treatment Adherence and Compliance
InTake Care: Development and Validation of an Innovative, Personalized Digital Health Solution for Medication Adherence Support in Cardiovascular Prevention
Inadequate medication adherence (MA) in chronic conditions, including cardiovascular prevention, represents an important risk factor.
- Conditions
- Hypertension, Treatment Adherence and Compliance, Digital Health
- Trial name
- InTakeCare (NCT06229171)
- Testing
- adherence support system based on a vocal assistant
- Where
- Italy
- Volunteers
- 206 people
- Sponsor
- Istituto Auxologico Italiano
Alcohol Drinking, Self Efficacy
ChangeGradients: Promoting Adolescent Health Behavior Change
As most adolescents visit a healthcare provider once a year, health behavior change interventions linked to clinic-based health information technologies hold significant promise for improving healthcare quality and subsequent…
- Conditions
- Alcohol Drinking, Self Efficacy, Adolescent Behavior, Risk-Taking
- Trial name
- NCT04110756
- Testing
- ChangeGradients
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Eating Disorders, Body Image Dissatisfaction
Development, Implementation, and Evaluation of the HADAS Program for the Prevention of Eating Disorders in Adolescent Female Athletes, Coaches, and Families.
Adolescent female athletes in aesthetic sports disciplines (such as rhythmic gymnastics, artistic gymnastics, synchronized swimming, and figure skating) face a complex interaction between general sociocultural beauty pressures…
- Trial name
- The HADAS (NCT07750301)
- Testing
- The HADAS Program
- Where
- Spain
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Dementia Prevention, Subjective Cognitive Impairment
The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia
This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro).
- Conditions
- Dementia Prevention, Subjective Cognitive Impairment, Mild Cognitive Impairment, Cognitive Change
- Trial name
- BHPROOF (NCT07364019)
- Testing
- Brain Health PRO
- Where
- Canada
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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