Clinical trials: Health Prevention
Ischemic Stroke, Transient Ischemic Attack
Trial of a Secondary Stroke Prevention Program
The purpose of this study is to determine whether an outpatient program can reduce the risk of recurrent stroke.
- Trial name
- NCT01071408
- Testing
- Stroke prevention care program
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Sepulveda Research Corporation
Occupational Health
Adaptation of SFA for HRW
The aim of this study is to pilot and test the feasibility, acceptability, and effectiveness of a Stress First Aid (SFA) intervention adapted for Harm Reduction Workers (HRWs) serving Persons Who Use Drugs.
- Trial name
- NCT07149155
- Testing
- Stress First Aid for Harm Reduction Workers
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Suzannah Creech
HIV Infections, Sexually Transmitted Diseases
Multi-component Intervention to Train Providers to Promote PrEP for Girls and Women in the Deep South
The goal of this study is to adapt evidence-based curriculum on HIV epidemiology and PrEP prescription to train family medicine physician trainees to take a thorough sexual history and discuss HIV/STI prevention and PrEP options…
- Trial name
- PrEP Pro (NCT06487390)
- Testing
- PrEP Pro training intervention
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Malaria
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
In areas of seasonal malaria transmission the burden of severe disease and mortality due to malaria is mainly among children under 5 years of age.
- Trial name
- NCT00712374
- Testing
- sulfadoxine-pyrimethamine plus amodiaquine
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Depression, Suicidality
Saving and Empowering Young Lives in Europe (Israel)
SEYLE is a health promoting program for adolescents in European schools. Its main objectives are to lead adolescents to better health through decreased risk-taking and suicidal behaviors, to evaluate outcomes of different…
- Trial name
- SEYLE-ISRAEL (NCT00906620)
- Testing
- QPR: question, persuade and refer (SEYLE)
- Where
- Israel
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Metabolic Syndrome, Risk Factors
CHANGE Cancer Alberta: A Primary Care Program for Cancer Prevention and Screening
The primary purpose of this trial will be to test the effectiveness of CHANGE intervention to increase physical activity, improve diets, reduce obesity and reverse Metabolic Syndrome among adult patients identified as at risk for…
- Trial name
- CHANGECaAB (NCT02893163)
- Testing
- CHANGE Intervention, Usual Care
- Volunteers
- 750 people
- Sponsor
- University of Alberta
Dental Caries
Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in Children
Despite advances in oral health care, cavities remain highly prevalent worldwide, especially among children. Conventional treatment methods focus on removing damaged tooth tissue but fail to completely eliminate or control…
- Trial name
- NCT07241052
- Testing
- oral-spray 0.9% NaCl physiological saline solution, Smile Care
- Where
- Vietnam
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Dementia, Cognitive Decline
Choral Singing For the Prevention of Dementia
To evaluate the efficacy of choral singing in the prevention of dementia and examine the underlying mechanisms using Magnetic Resonance Imaging (MRI) technique and a panel of peripheral biomarkers in venous blood and urine.
- Trial name
- NCT02919748
- Testing
- Choral Singing, Health Education Program
- Where
- Singapore
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Endometrial Cancer
Detection of Endometrial Cancer Through Risk Modelling
The study goal is to investigate a non-invasive approach to predict endometrial cancer (EC) risk, better understand disease progression and identify opportunities for intervention.
- Trial name
- DETECTR (NCT06268626)
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Subjects
Cocoa Intake for Health Promotion in Athletes
Athletes consume an extra of nutritional supplements every day with the purpose of improving their athletic performance, sometimes without being aware of their health.
- Trial name
- INDYCA (NCT03897114)
- Testing
- Cocoa group
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Universidad Europea de Madrid
Health Behavior
Oropharyngeal Administration of Colostrum
Infections are the main causes of morbidity and mortality in very low birth weight infants. Use of mother's own breast milk in feeding these babies is associated with a decreased risk of acquiring nosocomial infection.
- Trial name
- NCT02912585
- Testing
- Oropharyngeal administration of own mother's colostrum, Oropharyngeal administration of donor human milk
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Alzheimer's Disease, Aging
aeRobic Exercise and Cognitive Health
The purpose of the aeRobic Exercise and Cognitive Health (REACH) study is to understand how an aerobic exercise intervention might help promote brain health and cognition, thereby delaying the onset of clinical symptoms of…
- Trial name
- REACH (NCT02384993)
- Testing
- Enhanced Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Intravenous Injections, Vaccination
Efficacy of the Buzzy® Device on the Prevention of Health Care Induced Pediatric Pain in a Vaccination Center
In vaccination centers, venipunctures and vaccinations are sources of pain and anxiety in pediatric patients. Prior painful experiences can reduce the acceptance of later health care, hence making it more difficult for both…
- Trial name
- DOLVAX (NCT03220555)
- Testing
- Buzzy® device, EMLAPATCH (lidocaine, prilocaine)
- Where
- 3 sites in France
- Volunteers
- 220 people
- Sponsor
- Nantes University Hospital
Adolescent Relationship Abuse
School Health Center Healthy Adolescent Relationship Program
This community-partnered participatory study will work within high school health centers (SHCs) to test, via a 2-armed cluster randomized controlled trial, a multi-level intervention to reduce adolescent relationship abuse (ARA)…
- Trial name
- SHARP (NCT01678378)
- Testing
- SHARP Intervention
- Where
- United States
- Volunteers
- 1,012 people
- Sponsor
- University of Pittsburgh
Cancer
Getting Physical on Cigarettes - Smoking Cessation & Relapse Prevention
Adult female smokers will participate in an exercise-aided smoking cessation program, and will then be randomized into one of four cessation maintenance conditions: (a) Exercise Maintenance only (b) Exercise Maintenance + Relapse…
- Trial name
- NCT01305447
- Testing
- Exercise Behaviour Maintenance, Smoking Relapse prevention booklets, Contact control
- Where
- Canada
- Volunteers
- 413 people
- Sponsor
- University of Western Ontario, Canada
Impacted Mandibular Third Molar, Impacted Mandibular Third Molar Extraction
Preoperative Versus Postoperative Amoxicillin in Impacted Third Molar Surgery
This prospective observational cohort study evaluated the effects of the timing of amoxicillin use on postoperative recovery and oral health-related quality of life following impacted mandibular third molar surgery.
- Trial name
- NCT07857863
- Testing
- Amoxicillin
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Recep Tayyip Erdogan University
Cardiovascular Diseases
The LEARN Study for CVD Prevention
The investigator is testing a virtual environment (VE) to address prevention of HIV-related comorbidities.
- Trial name
- LEARN (NCT05242952)
- Testing
- Gaming in a virtual environment
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Yale University
HPV Infection, Preventive Health Services
PCOM2 - The Physician Communication Intervention, Version 2.0
Poor quality of primary care providers' vaccine recommendations lead to low adolescent human papillomavirus vaccination rates and hundreds of thousands of adolescents unnecessarily at risk for HPV-associated cancers and diseases.
- Trial name
- PCOM2 (NCT05336240)
- Testing
- Physician Communication 2 Virtual (PCOM2-virtual), Physician Communication Standard (PCOM-standard)
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Hypertension, Dietary Modification
Hypertension Prevention Program, Implementation and Scale up- a Hybrid Effectiveness Implementation Study
This is an effectiveness-implementation study to assess the effectiveness of a peer-led multi-component lifestyle program that will aim to lower BP among pre-hypertensive individuals in Nepal.
- Conditions
- Hypertension, Dietary Modification, Health Behavior
- Trial name
- NCT04899648
- Testing
- Behavioral Intervention Group
- Volunteers
- 500 people
- Sponsor
- University of Washington
Child Mental Disorder
Prevention of Child Mental Health Problems in Southeastern Europe
The aim of this study is to develop an adapted version of a low-cost parenting program (Parenting for Lifelong Health for Young Children, PLH) to the specific needs of families in three low- and middle income countries (LMICs) in…
- Trial name
- RISE (NCT03552250)
- Testing
- Parenting for Lifelong Health for Young Children
- Where
- 3 sites in Moldova, North Macedonia and 1 more
- Volunteers
- 140 people
- Sponsor
- Technische Universitaet Braunschweig
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