Clinical trials: Health Risk Behaviors, open to volunteers
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Atrial Fibrillation, Behavior
Mobile Health Technology-Enabled AFib Management
The overall objective of this proposal is to evaluate the effect on quality of life of a comprehensive digital atrial fibrillation (AFib) management tool that will empower patients to a) take an active role in learning about AFib…
- Trial name
- mTECH Afib (NCT06500988)
- Testing
- Corrie Virtual Atrial Fibrillation Management Program
- Where
- 2 sites in United States
- Volunteers
- 248 people
- Sponsor
- Johns Hopkins University
Cardiovascular Risk Factor
Afterschool Rx 2.0: Prescriptions to Afterschool Care for Pediatric Cardiovascular Risk Reduction
The goal of this clinical trial is to learn if "prescribing" afterschool care to children at risk for poor heart health later in life increases their physical activity and improves their heart health.
- Trial name
- ARx (NCT07096167)
- Testing
- Voucher for Afterschool Care
- Volunteers
- 48 people
- Sponsor
- Augusta University
Non Communicable Diseases, Health-risk Behaviours
Prevent Non-communicable Diseases Through Screening and Educating Emergency Department Attendees to Adopt Healthy Lifestyles
Objective: To examine the effectiveness of a general health promotion intervention based on self-determination theory in proactively helping emergency department (ED) attendees to adopt healthy lifestyles.
- Trial name
- NCT06889792
- Testing
- Theory of planned behaviour, Foot-in-the-door technique, Self-determination theory
- Where
- Hong Kong
- Volunteers
- 1,172 people
- Sponsor
- Chinese University of Hong Kong
Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA)
Twenty-four Hour Movement Behaviors and Atherosclerotic Risk
This observational study aims to investigate how 24-hour movement behaviors are associated with atherosclerotic risk in adults with rheumatoid arthritis. These behaviors include physical activity, sedentary behavior, and sleep.
- Conditions
- Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA), 24-Hour Movement Guidelines
- Trial name
- PASSARO (NCT07774507)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- São Paulo State University
Stress Resilience, Blood-Brain Barrier Integrity
Role of the Blood-Brain Barrier in Stress Resilience: Investigating New Pathways Towards Pharmacological Augmentation of Stress Resilience
The goal of this clinical trial is to better understand the relationship between blood-brain barrier (BBB) function and stress resilience and to investigate a potential causal role for BBB function in stress resilience in humans.
- Conditions
- Stress Resilience, Blood-Brain Barrier Integrity, Mental Health
- Trial name
- PHASR-PP (NCT06965868)
- Testing
- Metformin
- Where
- 3 sites in Germany, Poland and 1 more
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Leibniz-Institut für Resilienzforschung (LIR) gGmbH
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Non-communicable Diseases (NCD)
Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia
The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities.
- Trial name
- ENABLE (NCT07442318)
- Testing
- Structured lifestyle counseling integrated into ANC, Standard routine ANC
- Where
- 4 sites in Ethiopia
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Suicide, Mental Health Issue
Proximal Risk for Suicide in Adolescents
The central hypothesis is that biometric data can continuously monitor and allow for early identification/intervention of escalating suicidal symptoms.
- Trial name
- NCT06400810
- Testing
- Analog Devices Inc.
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Oregon Health and Science University
Depression During Pregnancy
Virtual Reality-enhanced Psychotherapy for Perinatal Depression
Perinatal depression is a growing public health crisis in the United States, affecting one in five individuals during pregnancy or postpartum.
- Trial name
- NCT07279311
- Testing
- Virtual reality behavioral activation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Stanford University
Type2diabetes, Heart Failure
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
This study aims to determine whether a 6-month multilevel intervention involving problem-solving training, exercise training and support from community health workers is more effective in improving outcomes for individuals with…
- Conditions
- Type2diabetes, Heart Failure, Obesity
- Trial name
- UNLOAD-HF (NCT06364644)
- Testing
- Community Champions, Homegrown Heroes
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Johns Hopkins University
Acute Coronary Syndrome (ACS), High Bleeding Risk (HBR)
Optimization and Validation of Quality Control Indicators for Coronary Revascularization Based on Antiplatelet Therapy
Study Purpose Coronary heart disease (CAD) is a leading global cause of death, with Acute Coronary Syndrome (ACS) as its acute and life-threatening subtype.
- Conditions
- Acute Coronary Syndrome (ACS), High Bleeding Risk (HBR), Coronary Artery Disease (CAD)
- Trial name
- NCT07354828
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Shenyang Northern Hospital
Solid Tumors
Physician and Patient Preferences for Cell Therapies in Advanced Solid Tumors
Cell therapies - including chimeric antigen receptor T-cell (CAR-T) therapy, tumor-infiltrating lymphocyte (TIL) therapy, T-cell receptor-engineered T-cell (TCR-T) therapy, and natural killer (NK) cell therapy - are emerging…
- Trial name
- NCT07813000
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 1,020 people
- Sponsor
- Zhejiang University
Exergaming, Metabolic Syndrome
Immersive Virtual Reality Exergames and Office Workers' Cardiometabolic Health
The worldwide increasing of prevalence of non-communicable diseases has grown the recognition of necessity for identifying the modifiable risk in preventing and managing these diseases.
- Trial name
- NCT06556784
- Testing
- 12-week at-home immersive virtual reality exergame
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Guangzhou University
Ultrasonography, Breast Neoplasm Female
Intelligent Remote Intervention for High-risk Breast Cancer Populations
The goal of this clinical trial is to compare the effects of modern remote health intervention regime with traditional in-person intervention strategies for high-risk breast cancer groups that with BI-RADS 3 or higher nodules.
- Conditions
- Ultrasonography, Breast Neoplasm Female, Breast Carcinoma, Health Education
- Trial name
- NCT06193707
- Testing
- the Remote Intervention, the Traditional Intervention
- Volunteers
- 1,250 people
- Sponsor
- Qianfoshan Hospital
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Adverse Childhood Experiences, Developmental Risk
Growing Up in Multifactorial Risk Conditions
The perinatal period brings significant physiological and emotional changes in mothers, linked to pregnancy, childbirth, and caring for a newborn.
- Conditions
- Adverse Childhood Experiences, Developmental Risk, Psychomotor Development Disorders, Neurodevelopmental Disorders
- Trial name
- CORE (NCT07477899)
- Testing
- Home visiting programme
- Where
- Italy
- Volunteers
- 352 people
- Sponsor
- IRCCS Eugenio Medea
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
HIV Infections, Sexual Health
Sexual Health of Sub-Saharan African Migrant Women Recently Diagnosed With HIV in Île-de-France: Missed Opportunities for Prevention
This study looks at the sexual health of women from Sub-Saharan Africa who recently found out they have HIV after arriving in Île-de-France.
- Conditions
- HIV Infections, Sexual Health, Migrants, Women's Health
- Trial name
- NCT07011017
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Pain Management, Patient Satisfaction
Pain Management for In-Office Gynecologic Procedures Using a Risk-Stratification Pain Calculator
The goal of this clinical trial is to learn how using a risk-stratification calculator to determine the risk of a patient experiencing severe pain during an in-office gynecologic procedure and subsequently assigning pain…
- Conditions
- Pain Management, Patient Satisfaction, Gynecologic Procedures
- Trial name
- NCT07311824
- Testing
- Pain Calculator
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Carle Foundation Hospital