Clinical trials: Health Volunteer
Traumatic Brain Injury
Improving Well-Being After TBI Through Structured Volunteer Activity
The purpose of this project is to determine if participating in volunteer activity improves the psychological well-being of individuals with traumatic brain injury (TBI).
- Trial name
- NCT01728350
- Testing
- HOPE - Helping Others through Purpose and Engagement
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Craig Hospital
Cerebrovascular Accident
The Effect of Dopamine on Motor Skills Training
This study will examine how dopamine, a brain chemical, affects motor training. Taken by mouth, dopamine can enhance motor training, especially during rehabilitation after brain damage.
- Trial name
- NCT00067275
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy, Cardiovascular Diseases
Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy Volunteers
The purpose of this study is to determine whether reducing the increase in plasma homocysteine concentrations following an oral methionine load affects vascular function in healthy volunteers, irrespective of the…
- Trial name
- NCT00126347
- Testing
- supplementation with betaine, serine, and folic acid
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wageningen Centre for Food Sciences
Diabetes Mellitus, Sarcoidosis
Salivary Proteins in Disease and Health
This study will examine saliva samples from healthy volunteers and patients with various diseases to learn more about how disease affects the mouth and salivary glands.
- Conditions
- Diabetes Mellitus, Sarcoidosis, Dental Caries, Sjorgren's Syndrome
- Trial name
- NCT00100204
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Transmission, Patient-Professional
Different Modalities in Reducing Airborne Particulate Concentrations During AGP for Health Volunteers
Several clinical procedures have been described as aerosol generating procedure (AGP), including nebulization, high-flow nasal cannula oxygen therapy, noninvasive ventilation, and bronchial hygiene treatment, etc.
- Trial name
- NCT04681599
- Testing
- Filter, Scavenger face tent
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Sjogren's Syndrome, Oral Health
Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk Population
Background: A person s dental health depends on many factors. Some are social, economic, or behavioral. Some are environmental. People with Sj(SqrRoot)(Delta)gren s Syndrome have a change in the amount and quality of saliva.
- Trial name
- NCT03327870
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Healthy Volunteers
Examining the Effects of Nasal High Flow Oxygen Therapy Compared to Non-invasive Ventilation in Health Volunteers
Respiratory failure is characterized by low levels of oxygen and high levels of carbon dioxide in the blood which causes difficulty breathing.
- Trial name
- NCT03902639
- Testing
- Phase 1 and 2, Phase 3
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Healthy Volunteers, Health Promotion
Dance-Mindfulness Intervention for Well-Being in Recreational Adults
This 12-week study protocol outlines a randomized controlled trial designed to evaluate the effectiveness of a Dance-Mindfulness intervention integrating Modern Theatre Dance with mindfulness-based embodied practices to enhance…
- Trial name
- DanceMind (NCT07262177)
- Testing
- Dance-Mindfulness Intervention
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Healthy Volunteer
Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health
The SEPAGES couple-child cohort is coordinated by an Inserm (French National Institute of Health and Medical Research) team of environmental epidemiology.
- Trial name
- SEPAGES-1337 (NCT02852499)
- Testing
- Urine sampling, Carry a GPS and BET, Carry pollution sensor
- Where
- France
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Gardasil Vaccine, Stem Cell Transplant
Gardasil Vaccination in Post Stem Cell Transplant Patients
Background: Gardasil , a recently approved vaccine for the sexually transmitted human papillomavirus (HPV), provides immunity to four types of HPV that are associated with genital warts and cervical, vaginal, and vulvar precancer…
- Conditions
- Gardasil Vaccine, Stem Cell Transplant, Immunogenicity
- Trial name
- NCT01092195
- Testing
- Gardasil
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Health, Subjective
Clinical Study of ALT-BB4 to Determine Tolerance, Safety and Pharmacokinetics in Healthy Volunteer
A Phase I Study to Evaluate the Tolerance, Safety and Pharmacokinetics of ALT-BB4 in Healthy Volunteers
- Trial name
- NCT05232175
- Testing
- ALT-BB4, 0.9%NaCl
- Where
- South Korea
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Alteogen, Inc.
Safety, Tolerability
A First-in-Human SAD and MAD Study in HV to Evaluate Oral YR011 Tablet
This is a Phase I clinical trial (protocol number: YR-011-B07) sponsored by Hangzhou Yirui Pharmaceutical Technology Co., Ltd., focusing on the novel oral small-molecule drug YR011 (active ingredient: PA032, a Kv1.3 channel…
- Conditions
- Safety, Tolerability, Pharmacokinetic
- Trial name
- NCT07878481
- Testing
- Kv1.3 potassium channel blocker (PA032, investigational oral small-molecule drug)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hangzhou Yirui Pharmaceutical Technology Co., Ltd
Health, Subjective
A Drug-Drug Interaction Study of CTL0801 and CTL0802 Compared to Coadministration in Healthy Adult Volunteers
This is a two-arm, open-label, single-sequence, multiple-dose, cross-over phase 1 study to evaluate the interaction between two investigational drugs by comparing and analyzing the pharmacokinetic interaction and safety of…
- Trial name
- NCT05002244
- Testing
- CTL0801 (Azilsartan), CTL0802 (Rosuvastatin), CTL0801 (Azilsartan) + CTL0802 (Rosuvastatin)
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Celltrion
Healthy
A Phase Ⅰa Study of Remimazolam Tosylate in Healthy Volunteers
The purpose of this study is to evaluate and compare the Pharmacokinetics/Pharmacodynamics and safety of Remimazolam Tosylate with midazolam in healthy volunteers
- Trial name
- NCT01970072
- Testing
- Remimazolam Tosylate, Midazolam
- Where
- China
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Intensive Care Unit, Muscle Strength
Normative Values for Peripheral Muscle Strength in Critical Patients and Healthy Individuals
Muscle strength is an important indicator of overall health and is a factor that has been associated with increased mortality in critical patients.
- Trial name
- HHD-ICU (NCT06296381)
- Where
- 4 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- University of Pernambuco
Smoking Cessation
A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine
This will be an open-label, randomised, 2-period, single-dose crossover study to determine the comparative bioavailability of cytisine following single-dose administration in healthy male and female subjects under fed and fasted…
- Trial name
- NCT03268343
- Testing
- Cytisine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Achieve Life Sciences
Iron Deficiency Anemia Treatment, Microbial Colonization
GI Effects of Iron in Healthy Volunteers
Over recent years there has been a lot of research looking at how the bacteria in our gut affects our health. Some medications are known to cause changes in gut bacteria.
- Conditions
- Iron Deficiency Anemia Treatment, Microbial Colonization, Iron-deficiency, Iron Deficiency Anemia
- Trial name
- NCT04705662
- Testing
- Lactulose breath test, Stool sample, Daily Diary
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr Anthony Hobson
Healthy Subjects, HPV
BD Onclarity HPV Assay on the BD COR Instrument: Self-collected Vaginal Swabs Validation
This study is being done to help IU Health validate a new method for HPV testing using self-collected vaginal swab samples. Volunteers will collect two vaginal swabs during a single study visit.
- Trial name
- NCT07909499
- Testing
- BD Cor OnClarity Self-Collection, BD Onclarity HPV Assay
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Schizophrenia, Bipolar Disorder
A Pilot Randomised Controlled Trial of a Health Champion Intervention
This study is a pilot RCT to evaluate the effectiveness and implementation challenges of an intervention using volunteer 'Health Champions' matched with service users to support service their physical health goals.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT04124744
- Testing
- Health Champions intervention, Control group-treatment as usual
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College London
Resistant Hypertension
JX09 SAD/MAD in Healthy Participants
This is a phase 1, randomized, double-blind, placebo-controlled, multi-part, single and multiple ascending dose study in healthy adult to test the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect of JX09…
- Trial name
- NCT06183671
- Testing
- JX09
- Where
- Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ji Xing Pharmaceuticals Australia Pty Ltd